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                  <text>Medical Journal of Indonesia Vol. 29 No. 2 2020 FKUI</text>
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                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020&#13;
MLH1 and MSH2 Mismatch Repair Protein Profile using Immunohistochemistry in Nepalese Colorectal Cancer Patients</text>
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                <text>colorectal cancer, immunohistochemistry, mismatch repair, MutL homolog 1, MutS homolog 2</text>
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                <text>BACKGROUND Hereditary nonpolyposis colorectal cancer, or Lynch syndrome, caused by germline mutations or genetic defects in mismatch repair (MMR) genes (MLH1, MSH2, PMS2, MSH6, and epithelial cellular adhesion molecule), is an autosomal dominant condition accounting for 2–5% of all colorectal carcinomas (CRCs). Reports on MMR loss in many populations are available; however, there are no reports on the frequency &#13;
of MMR protein expression in Nepalese cohorts. Therefore, this study was aimed to assess the expression profiles of MLH1 and MSH2 protein by immunohistochemistry (IHC) in Nepalese CRC patients.&#13;
METHODS This retrospective study used archived formalin-fixed paraffin-embedded tissue blocks from 43 Nepalese CRC patients. IHC staining was performed using MLH1 and MSH2 antibodies. IHC scoring analysis was assessed using semiquantitative scoring.&#13;
RESULTS Of the 43 CRC patients, 8 (18.6%) showed loss of staining for MLH1 antibody, 5 (11.6%) showed loss of staining for MSH2 antibody, and 4 (9.3%) showed loss of staining for both MLH1 and MSH2 antibodies.&#13;
CONCLUSIONS IHC is a potential screening method of determining the MMR expression &#13;
profile of Nepalese CRC patients. IHC can be performed in local clinical laboratories to find MMR protein defects in selected cases prior to expensive molecular tests.</text>
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                <text>Matrika Bhattarai, Wan Khairunnisa Wan Juhari, Raju Lama, Chin Bahadur Pun, Wardah Yusof, Wan Faiziah Wan Abdul Rahman, Andee Dzulkarnaen Zakaria, Khairul Bariah Ahmad Amin Noordin, Tilak R. Shrestha, Bin Alwi Zilfalil</text>
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                <text>Fakultas Kedokteran Universitas Indonesia</text>
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            <name>Date</name>
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                <text>Sri Wahyuni</text>
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          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
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              <elementText elementTextId="8909">
                <text>ISSN : 0853-1773</text>
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                <text>English</text>
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            <elementTextContainer>
              <elementText elementTextId="8913">
                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020</text>
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        <name>colorectal cancer</name>
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        <name>immunohistochemistry</name>
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        <name>Jurnal Internasional</name>
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        <name>mismatch repair</name>
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        <name>MutL homolog 1</name>
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        <name>MutS homolog 2</name>
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              <name>Title</name>
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                <elementText elementTextId="8693">
                  <text>Medical Journal of Indonesia Vol. 29 No. 2 2020 FKUI</text>
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      <name>Text</name>
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            <description>A name given to the resource</description>
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                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020&#13;
Zika, Chikungunya, and Dengue Viral Infections in Human Peripheral Blood Mononuclear Cells: Cell Susceptibility and Gene Expression</text>
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            <description>The topic of the resource</description>
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              <elementText elementTextId="8891">
                <text> chemokines, chikungunya virus, cytokines, dengue virus, mononuclear leukocytes, Zika virus</text>
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            <description>An account of the resource</description>
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                <text>BACKGROUND Infections of Zika (ZIKV), dengue (DENV), and chikungunya viruses (CHIKV) are presented with similar clinical symptoms; these often lead to misdiagnosis. Viremia levels and host immune responses may contribute to disease severity. This study was aimed to characterize the ability of ZIKV, CHIKV, and DENV to infect human &#13;
peripheral blood mononuclear cells (PBMCs) and assess the expression of tumor necrosis factor (TNF)-α, interleukin (IL)-10, and interferon gamma-induced protein (IP)-10 genes in response to the viral infections.&#13;
METHODS PBMCs were isolated from healthy donors using gradient centrifugation. Cells were infected with Indonesian isolates of ZIKV, CHIKV, and DENV for 48 hours. Plaque assays were performed to measure viable virus titers, while viral genomic RNA and the gene expression of TNF-α, IL-10, and IP-10 were determined using real-time &#13;
quantitative reverse transcription-polymerase chain reaction.&#13;
RESULTS The susceptibility of PBMCs to ZIKV, CHIKV, and DENV infection was observed, and the viable virus titer and viral genome quantity were found to be significantly higher in ZIKV and CHIKV. All viruses induced the expression of immune-related proteins. The TNF-α gene was upregulated by all viruses to relatively similar &#13;
levels. IL-10 expression was highest in response to ZIKV, followed by CHIKV. In contrast, &#13;
IP-10 expression was highly upregulated in DENV-infected cells and only moderately &#13;
expressed in ZIKV- and CHIKV-infected cells.&#13;
CONCLUSIONS ZIKV, CHIKV, and DENV clinical isolates infected PBMCs with different &#13;
levels of virus infectivity. The gene expression of IL-10 was highly upregulated in ZIKV &#13;
infection and IP-10 in DENV infection.</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="8893">
                <text>Ahmad Husein Alkaff, Benediktus Yohan, Usman Sumo Friend Tambunan, R. Tedjo Sasmono</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="8894">
                <text>Fakultas Kedokteran Universitas Indonesia</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020-07-02</text>
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          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8896">
                <text>Sri Wahyuni</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8897">
                <text>ISSN : 0853-1773</text>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
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            <name>Language</name>
            <description>A language of the resource</description>
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                <text>English</text>
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            <elementTextContainer>
              <elementText elementTextId="8901">
                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020</text>
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        <name>chemokines</name>
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        <name>chikungunya virus</name>
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      <tag tagId="159">
        <name>cytokines</name>
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      <tag tagId="160">
        <name>dengue virus</name>
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      <tag tagId="25">
        <name>Jurnal Internasional</name>
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        <name>mononuclear leukocytes</name>
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        <name>Zika virus</name>
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              <description>A name given to the resource</description>
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                  <text>Medical Journal of Indonesia Vol. 29 No. 2 2020 FKUI</text>
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            <description>A name given to the resource</description>
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                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020&#13;
The Implementation of Health Istithaah to The Pilgrims with Tuberculosis: A cross-Sectional Study in Jakarta, Indonesia</text>
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          <element elementId="49">
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                <text>eligibility, pilgrims, tuberculosis</text>
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                <text>BACKGROUND Based on the regulation of the Indonesian Ministry of Health No. 15 of 2016 about health istithaah for the Hajj, patients with tuberculosis (TB) can be categorized into ineligible or temporarily ineligible pilgrims. This study aimed to know the characteristics of pilgrims with TB and determined their level of fitness for fulfilling the health istithaah.&#13;
METHODS A cross-sectional study of pilgrims from Jakarta who were receiving TB treatment during the Hajj in 2018 was conducted with consecutive sampling. The secondary data was collected from the Hajj Integrated Computer Health System 2018, &#13;
TB registered form, and six-minute walk test (the fitness level data) conducted by the District Hajj Health Team at district health centers in DKI Jakarta and Pondok Gede before the Hajj embarkation in June–July 2018. The questionnaire to the Indonesian Hajj Health Team during pilgrimage was also included as additional data.&#13;
RESULTS Thirty-one pilgrims received TB treatment and completed the intensive phase of TB treatment, but 29 pilgrims had no symptoms. Among them, 2 patients had MDR-TB. Most of them were male aged ≥40 years old. Twelve pilgrims with TB have a &#13;
sufficient fitness. All pilgrims were able to run the pillars of the Hajj.&#13;
CONCLUSIONS Pilgrims with TB, including MDR-TB, who had completed the intensive phase with a negative sputum smear test were declared eligible for the Hajj with assistance.</text>
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            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="8881">
                <text>Ibnu Mas’ud, Ujainah Zaini Nasir, Ceva Wicaksono Pitoyo, Ikhwan Rinaldi</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>Fakultas Kedokteran Universitas Indonesia</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020-07-02</text>
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            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
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                <text>Sri Wahyuni</text>
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            </elementTextContainer>
          </element>
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            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8885">
                <text>ISSN : 0853-1773</text>
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            <name>Language</name>
            <description>A language of the resource</description>
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                <text>English</text>
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                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020</text>
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    <tagContainer>
      <tag tagId="164">
        <name>eligibility</name>
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      <tag tagId="163">
        <name>Jurnal Internasioanal</name>
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      <tag tagId="165">
        <name>pilgrims</name>
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        <name>tuberculosis</name>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="8693">
                  <text>Medical Journal of Indonesia Vol. 29 No. 2 2020 FKUI</text>
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      <name>Text</name>
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        <name>Dublin Core</name>
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                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020&#13;
Cybersex Addiction: An Overview of The Development and Treatment of A Newly Emerging Disorder</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="8867">
                <text> addictive behavior, internet, pornography, sexual online</text>
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            <description>An account of the resource</description>
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                <text>Cybersex addiction is a non-substance related addiction that involves online sexual activity on the internet. Nowadays, various kinds of things related to sex or pornography are easily accessible through internet media. In Indonesia, sexuality is usually assumed taboo but most young people have been exposed to pornography. It can lead to an addiction with many negative effects on users, such as relationships, money, and psychiatric problems like major depression and anxiety disorders. A few &#13;
instruments may be used to detect cybersex behavior. This review was aimed to provide a comprehensive discussion about cybersex addiction in Indonesian society and the importance of its screening for this condition to enable its early detection and subsequent management.</text>
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                <text>I Gusti Ngurah Agastya, Kristiana Siste, Martina Wiwie Setiawan Nasrun, Irmia Kusumadewi</text>
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                <text>Fakultas Kedokteran Universitas Indonesia</text>
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                <text>Sri Wahyuni</text>
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            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8873">
                <text>ISSN : 0853-1773</text>
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            <description>The file format, physical medium, or dimensions of the resource</description>
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                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020</text>
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                  <text>Medical Journal of Indonesia Vol. 29 No. 2 2020 FKUI</text>
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                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020&#13;
Causes of Mortality in A Neonatal Intensive Care Unit in Iran: One Year Data</text>
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                <text>mortality rate, neonatal intensive care unit, premature birth</text>
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                <text>BACKGROUND Neonatal mortality rate is a major health index. Approximately, 65% of all deaths in the first year of life occur during this 4-week period. The present study was conducted to investigate the mortality rates and causes of death in a neonatal intensive care unit (NICU) in Ahvaz, Iran in a year.&#13;
METHODS This cross-sectional study was conducted in the NICU of Sina Hospital in Ahvaz. Medical records were studied, and data from 1,040 newborns admitted to the NICU within one year (March 2016 to March 2017) were collected following a checklist. Relevant data of 123 died newborns were collected. Data were analyzed using SPSS, version 20 (SPSS Inc., USA).&#13;
RESULTS The mortality rate was 11.82% (123 cases) out of 1,040 newborns admitted to NICU. Most of the newborns (48.8%) died on days 1–7. The causes of death were respiratory distress syndrome (RDS) (34.1%), asphyxia (25.2%), anomalies (10.6%), sepsis (7.3%), intracerebral hemorrhage (8.1%), pulmonary hemorrhage (7.3%), and other causes (6.4%), such as hydrops, severe pneumothorax, severe renal failure, and others.&#13;
CONCLUSIONS The mortality rate in the NICU of this center was similar to that in other Iranian provinces. The most common causes of NICU mortality included prematurity and its complications, such as asphyxia and RDS. Thus, a strategic plan for reducing preterm delivery and asphyxia are necessary.</text>
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              <elementText elementTextId="8857">
                <text>Milad Azami, Shamim Jasemi, Yosef Khalifpur, Gholamreza Badfar</text>
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                <text>Fakultas Kedokteran Universitas Indonesia</text>
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            <name>Date</name>
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            <elementTextContainer>
              <elementText elementTextId="8860">
                <text>Sri Wahyuni</text>
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          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8861">
                <text>ISSN : 0853-1773</text>
              </elementText>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
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          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
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              <elementText elementTextId="8863">
                <text>English</text>
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            <elementTextContainer>
              <elementText elementTextId="8865">
                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020</text>
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      <tag tagId="171">
        <name>mortality rate</name>
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              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="8693">
                  <text>Medical Journal of Indonesia Vol. 29 No. 2 2020 FKUI</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020&#13;
Percutaneous Atrial Septal Defect Closure using Transesophageal Echocardiography without Fluoroscopy in A Pregnant Woman: A Case Report </text>
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          <element elementId="49">
            <name>Subject</name>
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                <text>atrial septal defect, catheterization, pregnant woman, transesophageal echocardiography</text>
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            <description>An account of the resource</description>
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                <text>Transcatheter closure is the treatment of choice for atrial septal defect (ASD); it has good efficacy and minimal complications. However, this approach in a pregnant woman is limited due to the risk of radiation exposure. A novel fluoroscopy-free technique has been introduced to reduce x-ray exposure. This case reported the experience of an &#13;
ASD transcatheter closure in a pregnant woman without fluoroscopy guidance. To the best of our knowledge, this is the first successful fluoroscopy-free technique for transcatheter closure in Indonesia. The case is a 26-year-old primigravida at 26 weeks’ gestational age with secundum ASD and pulmonary hypertension. Transcatheter closure was successfully performed with a Cera ASD occluder (Lifetech Scientific Corporation) no. 28 mm guided by transesophageal echocardiography. During the &#13;
procedure, transient supraventricular tachycardia was developed. There were no other major or minor periprocedural complications. ASD transcatheter closure in a pregnant woman without fluoroscopy is feasible, safe, and effective.</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8845">
                <text>Radityo Prakoso, Rina Ariani, Oktavia Lilyasari, Yovi Kurniawati, Sisca Natalia Siagian, Indriwanto Sakidjan, Poppy Soerwianti Roebiono, Anna Ulfah Rahajoe, Olfi Lelya, Aditya Agita Sembiring, Ganesja Moelia Harimurti</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="8846">
                <text>Fakultas Kedokteran Universitas Indonesia</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="8847">
                <text>2020-07-02</text>
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          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8848">
                <text>Sri Wahyuni</text>
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            </elementTextContainer>
          </element>
          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8849">
                <text>ISSN : 0853-1773</text>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
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            <name>Language</name>
            <description>A language of the resource</description>
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              <elementText elementTextId="8851">
                <text>English</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="8853">
                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Medical Journal of Indonesia Vol. 29 No. 2 2020 FKUI</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="8830">
                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020&#13;
Improving a Long-Acting Reversible Contraception usage by Understanding Client Perspectives</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
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              <elementText elementTextId="8831">
                <text>contraception, long-acting reversible contraception</text>
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            <description>An account of the resource</description>
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                <text>BACKGROUND Despite the limited use of long-acting reversible contraception (LARC) in Indonesia, they have proven to be cost-effective in family planning programs. This study was aimed to identify the elements of ideas and views that people hold and their association with the use of LARC (intrauterine devices and implants) as a means of &#13;
improving its utilization in Nusa Tenggara Barat (NTB) Province, Indonesia.&#13;
METHODS Data were derived from the Improving Contraceptive Mix Methods survey of 6,384 respondents in Bima District, Central Lombok, and North Lombok, NTB Province, in 2015. Confirmatory factor analysis was used to identify suitable elements of 19 variables and generate three ideation elements on attitude, knowledge, and &#13;
interpersonal communication. Subsequently, the association of three ideation elements with LARC use in NTB was examined. &#13;
RESULTS Multivariate analysis revealed that LARC use was higher among women with a positive attitude toward LARC and high frequency of interpersonal communication. Women with positive attitudes had 7 times greater odds of using LARC than women with negative attitudes (adjusted odds ratio [aOR] = 7.18; 95% confidence interval [CI] &#13;
= 6.09–8.55). Women with a high frequency of interpersonal communication were 2.4 times more likely to use LARC than women with low communication frequency (aOR = 2.40; 95% CI = 1.94–2.99).&#13;
CONCLUSIONS To increase the use of LARC in NTB, family planning programs should not only focus on improving women’s knowledge but also prioritizing the promotion of positive attitudes toward LARC and facilitating interpersonal communication.</text>
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                <text>Weni Kusumaningrum, Rita Damayanti, John Douglas Storey, Fitra Yelda&#13;
</text>
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                <text>Fakultas Kedokteran Universitas Indonesia</text>
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            <name>Date</name>
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                <text>2020-07-02</text>
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              <elementText elementTextId="8836">
                <text>Sri Wahyuni</text>
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          <element elementId="47">
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            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8837">
                <text>ISSN : 0853-1773</text>
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                <text>PDF</text>
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            <description>A language of the resource</description>
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                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020</text>
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                  <text>Medical Journal of Indonesia Vol. 29 No. 2 2020 FKUI</text>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020&#13;
Cytotoxic Effect of Natural Cuttlefish Bone Xenograft: An in Vitro and in Vivo Study</text>
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                <text>bone substitute, cuttlefish bone, cytotoxicity tests, xenograft</text>
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                <text>BACKGROUND Commercialized synthetic bone grafts are commonly used to replace the bone defect. Cuttlefish bone is naturally available and widely studied, but the specific cytotoxicity test has not been conducted. This study aimed to evaluate the cytotoxicity of the xenograft compared to commercial grafts.&#13;
METHODS We performed an in vitro test evaluating the viability of human mesenchymal stem cells (hMSCs) when cultured for 48 hours with the tested materials (cuttlefish bone graft and fabricated PerOssal®). The trypsinized itochondrial activity of the viable hMSC was assayed based on colorimetry of the formazan color change. The &#13;
tested material was considered nontoxic if &gt;70% of the hMSCs were viable. The in vivo cytotoxic effect was evaluated by implanting the graft material in the femoral muscle of New Zealand (NZ) white rabbits. Nine rabbits were used in each test (cuttlefish bone, PerOssal®, and NaCl 0.9%). The systemic acute pyrogenic effect was evaluated &#13;
based on 72 hours body weight changes and rectal temperature changes every 30 min in the first 3 hours and 72 hours post-implantation.&#13;
RESULTS The mean percentage of hMSC viability when cultured with cuttlefish bone graft and PerOssal® was comparable (93.47% and 105.37%, respectively, p = 0.240). The in vivo cytotoxicity on NZ rabbit was similar between all tested materials, as shown by the minor changes in body weight (&lt;10% body weight, p = 0.391) and rectal temperature (&lt;0.5°C, p = 0.127).&#13;
CONCLUSIONS Cuttlefish bone xenograft and fabricated PerOssal® have a similar non�cytotoxic effects on hMSCs and non-pyrogenic systemic effects on rabbits.</text>
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            <name>Creator</name>
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              <elementText elementTextId="8821">
                <text>Komang Agung Irianto, Suyenci Limbong</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="8822">
                <text>Fakultas Kedokteran Universitas Indonesia</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="8823">
                <text>2020-07-02</text>
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          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
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              <elementText elementTextId="8824">
                <text>Sri Wahyuni</text>
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            </elementTextContainer>
          </element>
          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8825">
                <text>ISSN : 0853-1773</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="42">
            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8826">
                <text>PDF</text>
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          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8827">
                <text>English</text>
              </elementText>
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          <element elementId="51">
            <name>Type</name>
            <description>The nature or genre of the resource</description>
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                <text>Text</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="8829">
                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020</text>
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      <tag tagId="180">
        <name>bone substitute</name>
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      <tag tagId="181">
        <name>cuttlefish bone</name>
      </tag>
      <tag tagId="182">
        <name>cytotoxicity tests</name>
      </tag>
      <tag tagId="25">
        <name>Jurnal Internasional</name>
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      <tag tagId="183">
        <name>xenograft</name>
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        <src>https://repository.horizon.ac.id/files/original/9738d64a80f41fbace4b2898e03bb409.pdf</src>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="8693">
                  <text>Medical Journal of Indonesia Vol. 29 No. 2 2020 FKUI</text>
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            </element>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8797">
                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020&#13;
Vitamin D₃ Levels in The Maternal Serum, Cord Blood, and Placenta of Preeclamptic Pregnant Women</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8798">
                <text>cord blood, serum, placenta, preeclampsia, vitamin D₃</text>
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                <text>BACKGROUND Preeclampsia is affected by oxidative stress, a free-radical produced as a by-product of endothelial damage, and antioxidant imbalance, such as vitamin D₃. This study was aimed to compare the vitamin D₃ levels in the placenta, cord blood, and maternal serum between patients with and without preeclampsia.&#13;
METHODS This cross-sectional study included 86 patients from Cipto Mangunkusumo Hospital and Tangerang District Hospital, in which 47 had preeclampsia (13 early-onset and 16 late-onset preeclampsia cases) and 39 had no preeclampsia. The placenta, cord blood, and maternal serum were taken after labor, then were analyzed according &#13;
to preeclampsia and non-preeclampsia; furthermore, the preeclampsia group was &#13;
analyzed in a subgroup of early- and late-onset preeclampsia. This is analyzed with either unpaired t-test, Mann–Whitney U test, or Kruskal–Wallis test.&#13;
RESULTS The maternal serum, cord blood, and placental tissue vitamin D₃ levels (16.30 [6.20–49.00], 11.80 [3.50–38.60], and 49.00 [22.00–411.00] ng/ml, respectively) of the preeclampsia group were similar to those of the non-preeclampsia group (13.50 [4.80–29.20], 11.70 [1.00–28.80], and 43.40 [11.80–153.00] ng/ml, respectively) (p = 0.459, 0.964, and 0.354, respectively). However, the placental tissue vitamin D₃levels in early-onset preeclampsia (79.00 [36.00–411.00] ng/ml) were higher than those in late-onset preeclampsia (40.00 [22.00–171.00] ng/ml) (p = 0.006).&#13;
CONCLUSIONS The vitamin D₃ levels between patients with and without preeclampsia were similar. However, the placental tissue vitamin D₃ levels in early-onset preeclampsia were higher than those in late-onset preeclampsia, possibly because of the different pathophysiology between early- and late-onset preeclampsia.</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8800">
                <text>Noroyono Wibowo, Rima Irwinda, Yohanes Handoko</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="8801">
                <text>Fakultas Kedokteran Universitas Indonesia</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8802">
                <text>2020-07-02</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8803">
                <text>Sri Wahyuni</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8804">
                <text>ISSN : 0853-1773</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="42">
            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8805">
                <text>PDF</text>
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            </elementTextContainer>
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          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8806">
                <text>English</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="51">
            <name>Type</name>
            <description>The nature or genre of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8807">
                <text>Text</text>
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          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="8808">
                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
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    <tagContainer>
      <tag tagId="184">
        <name>cord blood</name>
      </tag>
      <tag tagId="25">
        <name>Jurnal Internasional</name>
      </tag>
      <tag tagId="186">
        <name>placenta</name>
      </tag>
      <tag tagId="187">
        <name>preeclampsia</name>
      </tag>
      <tag tagId="185">
        <name>serum</name>
      </tag>
      <tag tagId="188">
        <name>vitamin D₃</name>
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  <item itemId="853" public="1" featured="1">
    <fileContainer>
      <file fileId="869">
        <src>https://repository.horizon.ac.id/files/original/7dce6db62b3c0ef852fde5d6973063c9.pdf</src>
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          <name>Dublin Core</name>
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          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="8693">
                  <text>Medical Journal of Indonesia Vol. 29 No. 2 2020 FKUI</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
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    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="8776">
                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020&#13;
Milk Protein Consumption Improves Muscle Performance and Total Antioxidant Status in Young Soccer Athletes: A Randomized Controlled Trial </text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8777">
                <text>milk proteins, muscles, soccer</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8778">
                <text>BACKGROUND Muscle performance and antioxidant balance are closely related to an athlete achievement. Milk proteins (whey and casein) contain essential and non-essential amino acids, which benefit muscle performance through increased antioxidant levels. This study was aimed to evaluate the effects of milk protein on muscle performance and total antioxidant status (TAS) in soccer athletes.&#13;
METHODS A randomized controlled trial was conducted on 20 males 16- to 18-year-old athletes at the Central Java Soccer Club in January 2018. For 28 days, the treatment group received 24 g/d of milk protein and the control group received 24 g/d of maltodextrin. Muscle performance was measured through a 20-m sprint, shuttle run, Illinois run, standing broad jump, sit-ups, push-ups, sit-and-reach test, and one�repetition maximum (1RM) leg extension. TAS was analyzed using the 2,2-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) method.&#13;
RESULTS The treatment group had a decreased shuttle run time (-0.16 [0.11] versus 0.08 [0.14] sec), greater increase in sit-ups (6.80 [2.57] versus 1.10 [2.84] times/60 sec), greater increase in push-ups (2.40 [1.78] versus 0.30 [1.77] times/60 sec), and greater increase in 1RM leg extension (32.00 [13.78] versus 3.50 [13.75] kg). After adjustments &#13;
for age, energy intake, carbohydrates, and pre-interventional performance, these parameters remained significantly improved after the intervention of milk protein. The TAS increase was greater in the treatment group than in the control group (0.36 [0.32] versus -0.12 [0.20] mmol/l) before and after adjustment for age, vitamin C, iron, &#13;
selenium intake, and TAS pre-treatment.&#13;
CONCLUSIONS Milk protein supplementation for 28 days increased muscle performance and TAS.</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8779">
                <text>Muhammad Irwan Setiawan, Hardhono Susanto, Martha Irene Kartasurya</text>
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            </elementTextContainer>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="8780">
                <text>Fakultas Kedokteran Universitas Indonesia</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8781">
                <text>2020-07-02</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8782">
                <text>Sri Wahyuni</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8783">
                <text>ISSN : 0853-1773</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="42">
            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8784">
                <text>PDF</text>
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            </elementTextContainer>
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          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="8785">
                <text>English</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="51">
            <name>Type</name>
            <description>The nature or genre of the resource</description>
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              <elementText elementTextId="8786">
                <text>Text</text>
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          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="8787">
                <text>Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 2 2020</text>
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        <name>Jurnal Internasional</name>
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      <tag tagId="189">
        <name>milk proteins</name>
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      <tag tagId="190">
        <name>muscles</name>
      </tag>
      <tag tagId="191">
        <name>soccer</name>
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