1 10 14 https://repository.horizon.ac.id/files/original/1226186086a670dfc35bdfc36d1f07d1.pdf 9b0ca54d91f237384fec95d341c8b081 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Medical Journal of Indonesia Vol. 30 No. 4 2021 FKUI Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 Acnowledgment of Reviewers Publisher An entity responsible for making the resource available Fakultas Kedokteran Universitas Indonesia Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-05 Contributor An entity responsible for making contributions to the resource Sri Wahyuni Rights Information about rights held in and over the resource ISSN : 0853-1773 Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource Text Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 https://repository.horizon.ac.id/files/original/41cd0e98ada35b637d7384480ee3e285.pdf ec911c9152b0d1b2355f4cea499f2423 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Medical Journal of Indonesia Vol. 30 No. 4 2021 FKUI Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 Cover, Editorial Board, Contents, Instructions fo Authors, Final Checklist & Submission Form Publisher An entity responsible for making the resource available Fakultas Kedokteran Universitas Indonesia Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-05 Contributor An entity responsible for making contributions to the resource Sri Wahyuni Rights Information about rights held in and over the resource ISSN : 0853-1773 Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource Text Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 https://repository.horizon.ac.id/files/original/0d2892e7cc4092288b0b6e4d41f23b94.pdf 32cc16ab46fa2cc1d9b3d939f92677cf Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Medical Journal of Indonesia Vol. 30 No. 4 2021 FKUI Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 The Importance of Identification for A Stress Urinary Incontinence after Pelvic Organ Prolapse Vaginal Repair (Editorial) Subject The topic of the resource Identification for A Stress Urinary Incontinence, Pelvic Organ Prolapse Vaginal Repair Description An account of the resource Pelvic organs prolapse (POP) and stress urinary incontinence (SUI) are the two specific health-related diseases in women globally. They may coexist in most affected patients because the predisposing factors are similar. Both diseases may emerge due to several conditions, such as anatomical impairment in the female pelvic floor support (i.e., fascial defects), muscular defect, denervation damage, or as a consequence of post POP vaginal repair. Women with POP may be continent despite losing vaginal and urethral support due to either kinking or external constriction of the urethra. Indeed, some women without a complaint of SUI presurgical may develop SUI following POP vaginal repair called postoperative stress urinary incontinence or de novo SUI. It is distinct from the continent patients with POP which may also have incontinence preoperatively called 'occult' or 'masked' SUI, and it will arise when the prolapse is corrected.The effect of POP surgery on the presence of SUI is complex. POP surgery can result in the cure of SUI, which preoperatively had been hidden by POP. Creator An entity primarily responsible for making the resource Hariyono Winarto Publisher An entity responsible for making the resource available Fakultas Kedokteran Universitas Indonesia Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-05 Contributor An entity responsible for making contributions to the resource Sri Wahyuni Rights Information about rights held in and over the resource ISSN : 0853-1773 Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource Text Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 Identification for A Stress Urinary Incontinence Jurnal Internasional Pelvic Organ Prolapse Vaginal Repair https://repository.horizon.ac.id/files/original/4e28e469c0b6e6c87d07f6ed846d7aa9.pdf b7e2a5e8a4694ca26f77644604ecbe5c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Medical Journal of Indonesia Vol. 30 No. 4 2021 FKUI Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 Perception and Preventive Behavior during COVID-19 Pandemic among Urban Residents in Banda Aceh, Indonesia: A Cross-Sectional Study Subject The topic of the resource COVID-19, perception, primary prevention Description An account of the resource BACKGROUND It is critical to evaluate the perception and preventive behavior of COVID-19 to formulate the optimal public health strategies for tackling the ongoing pandemic. This study aimed to enhance knowledge on the perception and preventive behavior toward COVID-19 among urban residents in Banda Aceh, Indonesia. METHODS A cross-sectional population-based survey was conducted from September to October 2020 using a structured questionnaire for the attendants of the six public health centers in Banda Aceh. Information about sociodemographic, perception, and preventive behavior toward COVID-19 were collected. The data were analyzed to find the association between the level of preventive behavior and covariates. RESULTS Among 1,067 respondents, 71.1% were female, 52.5% were aged between 40 and 60 years, 31.2% were university graduates, and >60% were unemployed with underlying diseases such as diabetes, hypertension, and cardiopulmonary diseases. The responses of each statement toward COVID-19 were varied. The multivariable model of covariates showed that females had good preventive behavior toward COVID-19 (adjusted OR: 1.849, 95% CI: 1.359–2.515). Urban residents in Banda Aceh with the underlying diseases had poor preventive behavior, while those with higher educational level and perception scores were more inclined to engage in good preventive behavior. CONCLUSIONS Most urban residents in Banda Aceh showed positive perception and propensity for adopting preventive measures. Health education is necessary for susceptible residents, such as males, less educated people, and people with underlying diseases. It should be stressed on specific practices and knowledge. Creator An entity primarily responsible for making the resource Husnah, Liza Salawati, Sakdiah, Nurul Nazira, Sarah Firdausa, Yusuf Syaeful Nawawi Publisher An entity responsible for making the resource available Fakultas Kedokteran Universitas Indonesia Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-05 Contributor An entity responsible for making contributions to the resource Sri Wahyuni Rights Information about rights held in and over the resource ISSN : 0853-1773 Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource Text Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 COVID-19 Jurnal Internasional perception primary prevention https://repository.horizon.ac.id/files/original/53b6c1e0fd88f13775fb087a0e28c1b8.pdf f79fd314b069f436fd67c66d4d0e32e2 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Medical Journal of Indonesia Vol. 30 No. 4 2021 FKUI Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 COVID-19 Potentially Causes Long-Term Deterioration of Lung Function: A Systematic Review and Meta-Analysis Subject The topic of the resource COVID-19, FEV1, pulmonary function test, SARS-CoV-2, spirometry Description An account of the resource BACKGROUND The COVID-19 is an emerging disease that commonly involves respiratory complaints, including acute respiratory distress syndrome. The effect of COVID-19 on pulmonary function is still unclear and only based on sporadic reports with a small sample size. This study aimed to compile evidence on the pulmonary function of patients who have recovered from COVID-19. METHODS Literature searching was conducted in PubMed, Embase, Google Scholar, Scopus, Web of Sciences, and CINAHL. Any types of studies published before June 26, 2020 and reported lung function tests of post-COVID-19 patients were included. Articles reporting data from early hospitalization were excluded. The risk of bias was measured using tools developed by the Joanna Briggs Institute. Meta-analysis was done using a meta statistical package in R and presented in the random effects model. RESULTS 378 recovered COVID-19 patients in 7 studies were included. The lung function measurement periods were varied, ranging from 14 days after hospitalization to 10 weeks after receiving rehabilitation. Meta-analyses found that the pooled mean of diffusion capacity of carbon monoxide in recovered COVID-19 patients was lower than 80% predicted, whereas the other parameters were normal. The forced vital capacity and total lung capacity showing restrictive lung disorders were significantly lower in the severe COVID-19 survivors. CONCLUSIONS COVID-19 has a negative impact on lung function for at least several weeks in the recovery period. Diffusion and restrictive problems could be the main long-term consequences of COVID-19. Creator An entity primarily responsible for making the resource Yudha Nur Patria, Rahmaningsih Mara Sabirin Publisher An entity responsible for making the resource available Fakultas Kedokteran Universitas Indonesia Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-05 Contributor An entity responsible for making contributions to the resource Sri Wahyuni Rights Information about rights held in and over the resource ISSN : 0853-1773 Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource Text Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 COVID-19 FEV1 Jurnal Internasional pulmonary function test SARS-CoV-2 spirometry https://repository.horizon.ac.id/files/original/e737f618f115e2bf5ecd9255aa9ed806.pdf 410d95abe4b27b700fefbf0e3f0274aa Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Medical Journal of Indonesia Vol. 30 No. 4 2021 FKUI Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 Immunogenicity and Safety of Adenovirus-Based Vector Vaccines for COVID-19: A Systematic Review and Meta-Analysis Subject The topic of the resource adenovirus vaccine, COVID-19, immunogenicity, safety, SARS-CoV-2 Description An account of the resource BACKGROUND Despite various research on vaccine development, severe acute respiratory syndrome coronavirus 2 infection continues to spread. Thus, developing a more effective vaccine for production and clinical efficacy is still in high demand. This review aimed to assess the immunogenicity and safety of adenovirus-based vector vaccines (Ad-vaccines) including Ad5-vectored, ChAdOx1 nCoV-19, rAd26-S or rAd5-S, and Ad26.COV2.S as the promising solutions for COVID-19. METHODS We conducted a systematic review and meta-analysis of clinical trials based on the preferred reporting items for systematic reviews and meta-analyses guidelines through PubMed, Scopus, Cochrane, and EBSCOhost until August 17, 2021. We implemented inclusion and exclusion criteria and assessed the studies using the US National Toxicology Program’s Office of Health Assessment and Translation risk of bias rating tool for human and animal studies. Pooled estimates of odds ratio (OR) were analyzed using fixed-effect model. RESULTS This systematic review yielded 12 clinical studies with a total of 75,105 subjects. Although the studies were heterogeneous, this meta-analysis showed that Ad-vaccine significantly increased protection and immune response against COVID-19 with a pooled efficacy of 84.68% compared to placebo (p<0.00001). Forest plot also indicated that Ad-vaccine conferred protection against moderate to severe COVID-19 with a pooled OR of 0.26 (p<0.00001). Ad-vaccine had also shown a good safety profile with local site pain and fever as the most common side effects. CONCLUSIONS Ad-vaccine had shown a good immunogenicity for COVID-19 with a good pooled efficacy and was proven safe for COVID-19 patients. Creator An entity primarily responsible for making the resource Ayers Gilberth Ivano Kalaij, Valerie Josephine Dirjayanto, Syarif Maulana Yusuf, Erni Juwita Nelwan Publisher An entity responsible for making the resource available Fakultas Kedokteran Universitas Indonesia Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-05 Contributor An entity responsible for making contributions to the resource Sri Wahyuni Rights Information about rights held in and over the resource ISSN : 0853-1773 Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource Text Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 adenovirus vaccine COVID-19 immunogenicity Jurnal Internasional safety SARS-CoV-2 https://repository.horizon.ac.id/files/original/ed5cbe78f149cae8e66c69f4929064f4.pdf a7c1ab034223d10735182a41003b1f62 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Medical Journal of Indonesia Vol. 30 No. 4 2021 FKUI Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 Prevalence and Clinical Potential of Extraspinal Incidental Findings in Lumbosacral Spine MRI of Patients with Suspected Disc Diseases Subject The topic of the resource incidental finding, lumbar spine, MRI Description An account of the resource BACKGROUND Incidental findings could be observed in organs close to the spine while reporting lumbosacral spine magnetic resonance imaging (MRI). This study aimed to report the prevalence and clinical potential of extraspinal incidental findings in lumbosacral MRI of patients with suspected disc diseases. METHODS This single-centered cross-sectional study was carried out on 420 consecutive adult patients who underwent lumbar spine MRI for suspected disc disease from January to July 2019. The MRI was checked for the presence of extraspinal incidental findings, and each finding was categorized according to the body organ and its clinical significance. Each MRI plane that best displayed the findings was recorded, and the association between the findings and patient's age and sex was determined. RESULTS Of 420 samples, 135 cases showed extraspinal findings (32.1%), and 7.6% of the patients displayed suspicious lesions. The urinary tract was the most common system (18.6%) to display both clinically significant (5.0%) and benign findings (13.6%), and the axial MRI section was the plane which showed most of the incidental findings. Incidental findings in any body system were rarely found in the younger patients. Females had significantly higher benign findings than males (p = 0.002). CONCLUSIONS The prevalence of extraspinal findings in lumbosacral spine MRI is high, and some are significant. Most findings are related to the urinary tract and best displayed in the axial plane. Creator An entity primarily responsible for making the resource Sameeah Abdulrahman Rashid Publisher An entity responsible for making the resource available Fakultas Kedokteran Universitas Indonesia Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-05 Contributor An entity responsible for making contributions to the resource Sri Wahyuni Rights Information about rights held in and over the resource ISSN : 0853-1773 Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource Text Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 incidental finding Jurnal Internasional lumbar spine MRI https://repository.horizon.ac.id/files/original/6650e4cc17f704a33aecc17b89046c45.pdf c7649e67e2d3a5ed5a3eb25597e00fcc Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Medical Journal of Indonesia Vol. 30 No. 4 2021 FKUI Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 Feasibility of The Modified 30-Second Sit-to-Stand Test in An Isolation Ward of Moderate COVID-19 Subject The topic of the resource COVID-19, functional capacity, modified 30-second sit-to-stand test Description An account of the resource BACKGROUND The recovery after prolonged immobilization during hospitalization because of COVID-19 is the primary goal of moderate to severe COVID-19 rehabilitation. Lower extremity muscle function assessment after immobilization is needed before starting mobilization. Hence, this study aimed to evaluate the feasibility of the modified 30-second sit-to-stand test (m30STS) as one of the prospective tools of functional capacity assessment in moderate COVID-19. METHODS This cross-sectional study recruited the subjects consecutively. All eligible subjects with oxygen saturation (SaO2) ≥95% with or without oxygen supplementation performed the m30STS following the Bohannon’s guidelines. The score of m30STS was calculated based on the number of stands completed within 30 sec. A higher score of the m30STS indicated better lower extremity function. RESULTS Mean score of m30STS was 13.3. No subjects had oxygen desaturation or increased heart rate, and no fall incidents occurred. CONCLUSIONS The m30STS is feasible and safe to evaluate lower extremity for moderate COVID-19 patients with SaO2 >95%. The absence of oxygen desaturation and increase in heart rate showed no increased oxygen consumption during the test. Creator An entity primarily responsible for making the resource Evi Rachmawati Nur Hidayati, Amien Suharti, Adis Tiara Suratinoyo, Silma Rahima Zahra, Nury Nusdwinuringtyas Publisher An entity responsible for making the resource available Fakultas Kedokteran Universitas Indonesia Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-05 Contributor An entity responsible for making contributions to the resource Sri Wahyuni Rights Information about rights held in and over the resource ISSN : 0853-1773 Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource Text Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 COVID-19 functional capacity Jurnal Internasional modified 30-second sit-to-stand test https://repository.horizon.ac.id/files/original/ba59085b9adf9bf01e4b809a8cea80f7.pdf 69ca3f79be007330507bded5786edd3d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Medical Journal of Indonesia Vol. 30 No. 4 2021 FKUI Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 Efficacy of Video-Based Psychotherapy in Reducing Psychological Distress of COVID-19 Patients Treated in Isolation Ward Subject The topic of the resource COVID-19, instructional film and audio, patient isolation, psychological distress, psychotherapy Description An account of the resource BACKGROUND Hospitalized patients with COVID-19 experience isolation during treatment, which may cause psychological distress. Thus, alternative ways to deliver psychological support are needed when face-to-face therapy is not possible. This study aimed to investigate the efficacy of video-based psychotherapy in reducing distress in COVID-19 patients treated in an isolation ward. METHODS This quasi-experimental trial without a control group included 42 COVID-19 patients aged 20–59 years. Participants were recruited conveniently in the COVID-19 isolation ward in Cipto Mangunkusumo Hospital, Jakarta, Indonesia. They watched three brief psychotherapy videos including relaxation, managing thoughts and emotions, and mindfulness for approximately 30 min. The videos were created by the Department of Psychiatry, Faculty of Medicine, Universitas Indonesia. Subjective units of distress scale (SUDS) was measured before and after watching all videos. Data were analyzed using the Wilcoxon-signed rank test. RESULTS All 42 subjects finished watching the videos. 31 subjects experienced a significant median decrease in SUDS score after the intervention. The effect size of the psychotherapy videos for the SUDS score was 0.485 (95% CI 0.302 to 0.634). CONCLUSIONS Watching psychotherapy videos is effective in reducing the SUDS score for COVID-19 patients in an isolation ward. Our brief video-based psychotherapy intervention has reduced psychological distress in hospitalized COVID-19 patients with limited access to face-to-face consultations due to the risk of disease transmission. Creator An entity primarily responsible for making the resource Petrin Redayani Lukman, Alvin Saputra, Sylvia Detri Elvira, Heriani, Alfi Fajar Almasyhur, Leonita Ariesti Putri, César Alberto Alfonso, Reina Rahma Noviasari Publisher An entity responsible for making the resource available Fakultas Kedokteran Universitas Indonesia Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-05 Contributor An entity responsible for making contributions to the resource Sri Wahyuni Rights Information about rights held in and over the resource ISSN : 0853-1773 Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource Text Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 COVID-19 instructional film and audio Jurnal Internasional patient isolation psychological distress https://repository.horizon.ac.id/files/original/ef01c9943cffcc7b4568d169298f45ee.pdf 07feea1817b1b9cbf1feb6596ac330a5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Medical Journal of Indonesia Vol. 30 No. 4 2021 FKUI Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 In Vivo Model of Hirschsprung-Associated Enterocolitis using Benzalkonium Chloride Subject The topic of the resource animal model, colitis, ganglions, Hirschsprung’s disease Description An account of the resource BACKGROUND Hirschsprung-associated enterocolitis (HAEC) is a life-threatening complication of Hirschsprung’s disease. Studies using animal models on the pathogenesis of HAEC are limited. Thus, this study aimed to establish a rat model of HAEC using topical application of 0.1% benzalkonium chloride (BAC) in the sigmoid colon. METHODS 55 male Sprague Dawley rats aged 10−12 weeks old were separated into 11 groups. The control group (n = 5) was euthanized on day-7, and the other 10 groups (n = 5 in each group) treated with 0.1% BAC in the sigmoid colon for 15 min to induce Hirschsprung’s disease were euthanized on day-7, -10, -12, -14, -17, -19, -21, -23, -25, and -28. The sigmoid colon was excised, fixed in formalin, and sectioned for histological examinations with hematoxylin and eosin staining. The degree of HAEC was compared within all groups. RESULTS Rats that were sacrificed on day-7 to -12 showed the 1st degree or early HAEC, which was most likely caused by BAC application. The 2nd degree of HAEC occurred in rats that were sacrificed on day-14 that showed a macrophage infiltration in the sigmoid colon, thus fulfilled the initial criteria for HAEC (p = 0.0025 versus control). The degree of enterocolitis increased with time, and the highest degree was found in rats that were sacrificed on day-28 (p<0.001 versus control). CONCLUSIONS Topical application of 0.1% BAC for 15 min was successfully produced HAEC model in rats, which was occurred on day-14 after the application. This model provides a useful resource for further research on the pathogenesis of HAEC Creator An entity primarily responsible for making the resource Iskandar Rahardjo Budianto, Agus Firmansyah, Yefta Moenadjat, Ahmad Aulia Jusuf, Vivian Soetikno Publisher An entity responsible for making the resource available Fakultas Kedokteran Universitas Indonesia Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-05 Contributor An entity responsible for making contributions to the resource Sri Wahyuni Rights Information about rights held in and over the resource ISSN : 0853-1773 Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource Text Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 4 2021 animal model colitis ganglions Hirschsprung’s disease Jurnal Internasional