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                  <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI</text>
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                <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI&#13;
Acnowledgment of Reviewers on Behalf of the Editorial Board of the Medical Journal of Indonesia, we would like to acknowledge with thanks to the following reviewers who have assisted us by providing reviews in the period between </text>
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                <text>Abdul Gofir, Yogyakarta, Indonesia&#13;
Adianto Nugroho, Jakarta, Indonesia&#13;
Agian Jeffilano Barinda, Jakarta, Indonesia&#13;
Agung Dewanto, Yogyakarta, Indonesia&#13;
Agus Supartoto, Yogyakarta, Indonesia&#13;
Agustini Utari, Semarang, Indonesia&#13;
Ahmad Yanuar Safri, Jakarta, Indonesia&#13;
Aida Rosita Tantri, Jakarta, Indonesia&#13;
Akhmadu Muradi, Jakarta, Indonesia&#13;
Alireza Razavi, Sari, Iran&#13;
Amanda Rumondang, Jakarta, Indonesia&#13;
Amiliana Soesanto, Jakarta, Indonesia&#13;
Andhika Rachman, Jakarta, Indonesia&#13;
Andree Kurniawan, Tangerang, Indonesia&#13;
Anggi Gayatri, Jakarta, Indonesia&#13;
Anita Lidesna Shinta Amat, Kupang, Indonesia&#13;
Anna Meiliana, Sumedang, Indonesia&#13;
Anugrah Santoso, Surabaya, Indonesia&#13;
Arifa Mustika, Surabaya, Indonesia&#13;
Ashish Trivedi, Brunei Darussalam&#13;
Atma Gunawan, Malang, Indonesia&#13;
Bambang Budi Siswanto, Jakarta, Indonesia&#13;
Bambang Setiawan, Banjarmasin, Indonesia&#13;
Bambang Widyantoro, Jakarta, Indonesia&#13;
Beny Rilianto, Jakarta, Indonesia&#13;
Budi Kadek Santosa, Bali, Indonesia&#13;
Budi Riyanto Wreksoatmodjo, Jakarta, Indonesia&#13;
Cri Sajjana Prajna Wekadigunawan, Jakarta, Indonesia&#13;
Datesh Daneshwar, Kuala Lumpur, Malaysia&#13;
Dawood S. Abdoun, Baghdad, Iraq&#13;
Dedy Pratama, Jakarta, Indonesia&#13;
Dhama Shinta Susanti, Jakarta, Indonesia&#13;
Dian Marta Sari, Sumedang, Indonesia&#13;
Dita Aditianingsih, Jakarta, Indonesia&#13;
Doddy M. Soebadi, Surabaya, Indonesia&#13;
Dodi Safari, Jakarta, Indonesia&#13;
Dyah Kanya Wati, Bali, Indonesia&#13;
Ediana Sutjiredjeki, Bandung, Indonesia&#13;
Eka Dian Safitri, Jakarta, Indonesia&#13;
Erni Hernawati Purwaningsih, Jakarta, Indonesia&#13;
Faisal Parlindungan, Jakarta, Indonesia&#13;
Fariz Nurwidya, Jakarta, Indonesia&#13;
&#13;
Femmy Nurul Akbar, Jakarta, Indonesia&#13;
Fithriyah, Jakarta, Indonesia&#13;
Fitri Octaviana, Jakarta, Indonesia&#13;
Fitriana Murriya Ekawati, Yogyakarta, Indonesia&#13;
Fransiska Kaligis, Jakarta, Indonesia&#13;
Gede Wirya Kusuma Duarsa, Bali, Indonesia&#13;
Goot Heah Khor, Selangor, Malaysia&#13;
Grace Wangge, Jakarta, Indonesia&#13;
Hafil Budianto Abdulgani, Jakarta, Indonesia&#13;
Hamed Jafarpour, Sari, Iran&#13;
Hartanto Bayuaji, Bandung, Indonesia&#13;
Hervita Diatri, Jakarta, Indonesia&#13;
Husnawati Syaiful Amri, Bogor, Indonesia&#13;
I Gusti Ngurah Gunawan Wibisana, Jakarta, Indonesia&#13;
I Wayan Sudarsa, Bali, Indonesia&#13;
Idayani Panggalo, Makassar, Indonesia&#13;
Ifran Saleh, Jakarta, Indonesia&#13;
Ignatius Riwanto, Semarang, Indonesia&#13;
Ikhwan Rinaldi, Jakarta, Indonesia&#13;
Imam Budi Putra, Medan, Indonesia&#13;
Ina Susianti Timan, Jakarta, Indonesia&#13;
Indarwati Setyaningsih, Yogyakarta, Indonesia&#13;
Indra Tri Mahayana, Yogyakarta, Indonesia&#13;
Irwan Supriyanto, Yogyakarta, Indonesia&#13;
Islamudin Ahmad, Samarinda, Indonesia&#13;
Jamal Zaini, Jakarta, Indonesia&#13;
Jutti Levita, Sumedang, Indonesia&#13;
Kade Yudi Saspriyana, Bali, Indonesia&#13;
Ketut Dewi Kumara Wati, Bali, Indonesia&#13;
Klara Yuliarti, Jakarta, Indonesia&#13;
Krisna Yuarno Phatama, Malang, Indonesia&#13;
Kuntjoro Harimurti, Jakarta, Indonesia&#13;
Muhammad Alamsyah Aziz, Bandung, Indonesia&#13;
Maruhum Bonar Hasiholan Marbun, Jakarta, Indonesia&#13;
Mas Rizky Anggun Adipurna Syamsunarno,&#13;
Sumedang, Indonesia&#13;
Meer M. Chisthi, Kerala, India&#13;
Mendy Hatibie, Manado, Indonesia&#13;
Miftah Pramudyo, Sumedang, Indonesia&#13;
Muchtaruddin Mansyur, Jakarta, Indonesia&#13;
Muhammad Adrianes Bachnas, Solo, Indonesia&#13;
Mujaddid Idulhaq, Sukoharjo, Indonesia&#13;
&#13;
276 Med J Indones 2022;31(4)&#13;
&#13;
Nafrialdi, Jakarta, Indonesia&#13;
Nandita Melati Putri, Jakarta, Indonesia&#13;
Niken Puruhita, Semarang, Indonesia&#13;
Ninik Sukartini, Jakarta, Indonesia&#13;
Noroyono Wibowo, Jakarta, Indonesia&#13;
Noto Dwimartutie, Jakarta, Indonesia&#13;
Novi Silvia Hardiany, Jakarta, Indonesia&#13;
Nuswil Bernolian, Palembang, Indonesia&#13;
Pangastuti Nuring, Yogyakarta, Indonesia&#13;
Ponco Birowo, Jakarta, Indonesia&#13;
Prahara Yuri, Yogyakarta, Indonesia&#13;
Prasandhya Astagiri Yusuf, Jakarta, Indonesia&#13;
Praseno Hadi, Jakarta, Indonesia&#13;
Purwantyastuti Ascobat, Jakarta, Indonesia&#13;
Pustika Amalia Wahidiyat, Jakarta, Indonesia&#13;
Raden Maula Rifada, Bandung, Indonesia&#13;
Ratih Dewi Yudhani, Surakarta, Indonesia&#13;
Renti Mahkota, Jakarta, Indonesia&#13;
Rifkanisa Faiza, Yogyakarta, Indonesia&#13;
Rinawati Rohsiswatmo, Jakarta, Indonesia&#13;
Rino Alvani Gani, Jakarta, Indonesia&#13;
Rosa Falerina, Surabaya, Indonesia&#13;
Rosadi Seswandhana, Yogyakarta, Indonesia&#13;
Rozi Aditya Aryananda, Surabaya, Indonesia&#13;
Ruby Riana Asparini, Malang, Indonesia&#13;
&#13;
Rudi Putranto, Jakarta, Indonesia&#13;
Ryan Ranitya, Jakarta, Indonesia&#13;
Saleha Sungkar, Jakarta, Indonesia&#13;
Sandra Widaty, Jakarta, Indonesia&#13;
Sasmojo Widito, Malang, Indonesia&#13;
Sentot Santoso, Hesse, Germany&#13;
Siti Sa’diah, Bogor, Indonesia&#13;
Sofia Wardhani, Jakarta, Indonesia&#13;
Sri Linuwih Menaldi, Jakarta, Indonesia&#13;
Sunarno, Semarang, Indonesia&#13;
Syarifah Dewi, Jakarta, Indonesia&#13;
Syougie, Jakarta, Indonesia&#13;
Thanusak Tatu, Chiang Mai, Thailand&#13;
Theddeus O. H. Prasetyono, Jakarta, Indonesia&#13;
Tyas Priyatini, Jakarta, Indonesia&#13;
Vina Yanti Susanti, Yogyakarta, Indonesia&#13;
Virna Dwi Oktariana, Jakarta, Indonesia&#13;
Yahdiana Harahap, Jakarta, Indonesia&#13;
Yefta Moenadjat, Jakarta, Indonesia&#13;
Yopie Afriandi Habibie, Banda Aceh, Indonesia&#13;
Yudianita Kesuma, Palembang, Indonesia&#13;
Yulia Ariani, Jakarta, Indonesia&#13;
Yurisal Akhmad Dany, Yogyakarta, Indonesia&#13;
Zairin Noor Hilmy, Banjarmasin, Indonesia&#13;
Zanbagh Pirastehfar, Sari, Iran</text>
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                <text>November 30th 2022.</text>
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                  <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI</text>
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                <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI&#13;
Association between Interleukin-2 (rs2069762) Gene Polymorphism and FVIII Inhibitor Development in Indonesian Patients with Severe Hemophilia A </text>
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                <text>antibodies, factor VIII, hemophilia A, interleukin-2, single nucleotide&#13;
polymorphism</text>
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                <text>BACKGROUND Factor VIII (FVIII) inhibitors in hemophilia A (HA) patients render FVIII&#13;
replacement therapy ineffective. Although its development cause is unclear, it has&#13;
been classified into therapeutic and genetic-related etiologies. Single nucleotide&#13;
polymorphisms (SNPs) in several cytokine genes, including interleukin (IL)-2, could&#13;
increase the risk of FVIII inhibitor development. This study aimed to evaluate the&#13;
association between IL-2 (rs2069762) gene SNP and FVIII inhibitor development in&#13;
Indonesian patients with severe HA.&#13;
METHODS The IL-2 (rs2069762) gene SNP was examined in 119 HA patients. The presence&#13;
of FVIII inhibitors was quantified using an enzyme-linked immunosorbent assay, with a&#13;
titer of &lt;0.28 ng/ml considered negative. Patients were divided into two groups: 59&#13;
with FVIII inhibitors (positive group) and 60 without inhibitors (negative group). The&#13;
genotype of the subjects was determined using peripheral blood mononuclear cells&#13;
and tetra-primer amplification refractory mutation system-polymerase chain reaction.&#13;
RESULTS There was no association between IL-2 (rs2069762) gene polymorphism and&#13;
FVIII inhibitor development on genotypes (p = 0.138) and allele frequencies (p = 0.780).&#13;
CONCLUSIONS IL-2 (rs2069762) gene polymorphism is not a risk factor in the&#13;
development of FVIII inhibitors in Indonesian patients with severe HA. Thus, further&#13;
polymorphism studies in other cytokine genes are required to gain a comprehensive&#13;
understanding of the FVIII inhibitor development.</text>
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                <text>Sri Marwanta, Faizal Muhammad,  Suradi Maryono, Kun Salimah, Sihwidhi Dimas Sudarmadi, Bambang Purwanto, Brian Wasita, Tonang Dwi Ardyanto,  Soetrisno </text>
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                <text>https://doi.org/10.13181/mji.oa.236439</text>
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                <text>February 27, 2023</text>
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                  <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI</text>
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          <element elementId="50">
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                <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI&#13;
Basic Medical Research Novel Point Mutation and Intronic Mutations of RB1 Gene in Retinoblastoma Patients in Indonesia </text>
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                <text>germline mutation, RB1 gene, retinoblastoma</text>
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                <text>BACKGROUND Retinoblastoma (RB) is an inherited disorder caused by the RB1 gene&#13;
mutation in retinal cells or germline mutation. Identifying the specific mutation is&#13;
crucial for prognosis, inheritance risk assessment, and treatment planning. This study&#13;
aimed to identify the germline mutation in the RB1 gene in patients with RB and their&#13;
parents from the eastern part of Indonesia.&#13;
METHODS This observational analytic study recruited patients with RB and their&#13;
parents between 2016 and 2018 at Dr. Wahidin Sudirohusodo Hospital, Makassar,&#13;
Indonesia. The normal control subjects were children from the outpatient clinic at&#13;
the Department of Ophthalmology, Universitas Hasanuddin Hospital. Ophthalmic&#13;
examinations and peripheral blood tests were performed in RB patients, their parents,&#13;
and control subjects. Genomic DNA was isolated from blood leukocytes and amplified&#13;
using conventional PCR. Hotspot exons 8, 10, 14, 17, and 22 were screened for mutations&#13;
using the Sanger method.&#13;
RESULTS There were 21 patients with RB (16 unilateral and 5 bilateral) and 14 normal&#13;
subjects. Of the 184 variations detected in RB patients, 164 were also found in normal&#13;
subjects. 19 intronic mutations in introns 10, 16, 17, and 21, and 1 novel missense mutation&#13;
in exon 17 were identified. Parental testing revealed 8 substitutions in exon 17 and 5&#13;
intronic mutations in introns 16 and 17 of the parents. None of the variations in exons&#13;
were passed to their children.</text>
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                <text>Batari Todja Umar, Ulfah Rimayanti, Halimah Pagarra, Budu, Nasrum Massi, Habibah Setyawati Muhiddin</text>
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                <text>https://doi.org/10.13181/mji.oa.236544</text>
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                <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI&#13;
Corrigendum: Comparison of Ultrasonography and Fluoroscopy as Guides for Extracorporeal Shock Wave Lithotripsy in Nephrolithiasis Patients: A Systematic Review </text>
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                <text>Gede Wirya Kusuma Duarsa, Christian Nurtanto Putra,&#13;
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Tirtayasa, Firman Pribadi</text>
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Gede Wirya Kusuma Duarsa,1,2 Christian Nurtanto Putra,3&#13;
Kevin Ivandi,3 Kadek Adit Wiryadana,3 Pande Made Wisnu&#13;
Tirtayasa,1 Firman Pribadi2&#13;
1Department of Urology, Faculty of Medical and Health Science,&#13;
Universitas Udayana, Sanglah General Hospital, Denpasar, Indonesia,&#13;
2Faculty of Medical and Health Science, Universitas Muhammadiyah&#13;
Yogyakarta, Yogyakarta, Indonesia,&#13;
3Faculty of Medical and Health Science, Universitas Udayana, Denpasar,&#13;
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                <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI&#13;
Medical Journal of Indonesia, Editorial Board, Contents, Index Medical Journal of Indonesia </text>
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                <text>The Medical Journal of Indonesia (abbr: Med J Indones) was founded in 1991 as the Medical Journal of the&#13;
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quarterly, consistently, and continuously, covering a wide range of medical subject and&#13;
issues from every medical specialist aspect. In 1995 the name was changed to Medical&#13;
Journal of Indonesia which reflected the widening of its coverage beyond Universitas&#13;
Indonesia. The mission of our journal is to provide biomedical scientist, clinical,&#13;
and public health researchers as well as other health care professionals with&#13;
&#13;
the media to published their research works. Starting from 2011, Deutsch-&#13;
Indonesische Gesellschaft für Medizin (DIGM) Medical Journal has been&#13;
&#13;
merged into Medical Journal of Indonesia. This also means that DIGM is&#13;
officially collaborating with Medical Journal of Indonesia and Faculty of&#13;
Medicine Universitas Indonesia as the owner and publisher. The mission&#13;
of the Medical Journal of Indonesia is to improve health care management&#13;
by providing high-quality articles from Indonesia and worldwide.</text>
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Multiple Vaginal Stones Secondary to An Ectopic Ureter in An Adult Female Patient: A Case Report </text>
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                <text>ectopic ureter, ureteroneocystostomy, vaginal stone</text>
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                <text>Vaginal stones are a rare condition that can be&#13;
misdiagnosed as other diseases.1,2 The overall incidence&#13;
is unclear because most cases are only reported as case&#13;
studies. In 1900, Halban was the first to report a case&#13;
of vaginal stone that developed into a giant vaginal&#13;
cystocele.1&#13;
Vaginal stones can be classified into primary or&#13;
secondary based on their etiology.2&#13;
&#13;
Primary vaginal&#13;
stones result from stagnant urine within the vagina,&#13;
while secondary vaginal stones are caused by a nidus&#13;
from the deposition of inorganic salts around foreign&#13;
bodies in the vagina.3&#13;
&#13;
They are commonly caused by&#13;
congenital genitourinary abnormalities, such as an&#13;
ectopic ureter, trauma, and urethrovaginal fistula&#13;
secondary to scarring after gynecologic surgeries.3&#13;
Ectopic ureter is often associated with a duplex&#13;
renal system, which can be classified into a complete&#13;
and incomplete double system ureter. Ectopic ureter&#13;
insertion into the vagina can form vaginal stones due&#13;
&#13;
to urinary stasis and repeated infection.1,3 In this report,&#13;
we presented a case of multiple giant vaginal stones&#13;
due to an ectopic ureter associated with a duplex renal&#13;
system in an adult female patient.</text>
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                <text>Muhammad Adi Satrio Lazuardi,  Andrie Rhomdhon Kurniawan, Pradana Nurhadi, Besut Daryanto </text>
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                <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI&#13;
Short Stature and Stunting in Indonesia: Problems and Innovative Alternative Solutions </text>
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                <text>Height stature, mostly influenced by genetic traits,&#13;
is also influenced by environment and nutrition. There&#13;
has been an increasing national average height in some&#13;
countries in the last 30 years. The national average&#13;
height is related to the national health care system&#13;
and nutritional status. Therefore, a higher national&#13;
average height is correlated with better health care,&#13;
especially nutritional support. A recent study has&#13;
shown that a higher height is related to a lower risk&#13;
of several health traits, i.e., cardiovascular disease.1&#13;
Togas et al2&#13;
also found that children with higher height&#13;
have higher cognitive value (intelligence quotient). To&#13;
improve this indicator, the program can only target the&#13;
high-risk population, including children and teenagers&#13;
who are still in the growth phase. Based on data from&#13;
NCD Risk Factor Collaboration, Indonesia has been&#13;
categorized as one of the top 10 countries with the&#13;
shortest average height,3&#13;
&#13;
indicating the importance of&#13;
improving the health care system, especially nutritional&#13;
support for children and teenagers, to increase this&#13;
national average height indicator.&#13;
The combination of short stature and severe&#13;
malnutrition will lead to a stunting condition. Togas&#13;
et al2&#13;
found that stunting is associated with a lacking&#13;
cognitive development. Additionally, it may cause&#13;
mental disorders and chronic disease risks in the&#13;
future. Therefore, programs on reducing stunting&#13;
should target a wider population, including children&#13;
and high-risk populations such as pregnant women&#13;
and newborns. Gunardi et al4&#13;
&#13;
found that the lower&#13;
mother’s educational level (less time) was the&#13;
significant factor for stunting. Although the incidence&#13;
of stunting in Indonesia reaches 22% in newborns,&#13;
Indonesia is still one-third of countries with a high&#13;
stunting condition. Gunardi et al4&#13;
&#13;
found an irony that&#13;
stunting was still found in the capital city of Jakarta in&#13;
2014. Therefore, the Ministry of Health has prioritized&#13;
&#13;
stunting elimination as part of the national healthcare&#13;
transformation by reducing the incidence to less than&#13;
15% in 2 years.5&#13;
&#13;
As stunting management requires a&#13;
comprehensive and multi-sectoral approach involving&#13;
the health, nutrition, water, sanitation, and education&#13;
sectors, the government has encouraged educational&#13;
innovations and program applications for stunting&#13;
screening and monitoring in high-risk population.&#13;
The most important way to solve short stature/&#13;
&#13;
stunting is to ensure the nutritional intake for the high-&#13;
risk population in the long term. Recently, innovative&#13;
&#13;
ready-to-use therapeutic foods (RUTFs) containing&#13;
highly dense nutrition and enriched energy have been&#13;
developed to address these problems. Sjarif et al6&#13;
found that the daily growing-up milk (formulated milk&#13;
for children aged 1–3 years), as an example of RUTFs,&#13;
could decrease the risk of stunting. However, it is&#13;
costly in the long term, which may not be suitable for&#13;
the high-risk population with middle or low income.&#13;
Thus, innovation in affordable supplemental foods for&#13;
the high-risk stunting population is needed.&#13;
Indonesia, with its rich natural resources, should&#13;
take this advantage to develop a potential affordable&#13;
supplemental food against the stunting problem.&#13;
Personally, I am really grateful to be a part of research&#13;
group in the Medical Technology Cluster in the&#13;
Indonesia Medical Education and Research Institute,&#13;
Faculty of Medicine, Universitas Indonesia to carry out&#13;
this important project. The project is expected to find&#13;
alternative affordable supplemental food for high-risk&#13;
populations. This alternative supplemental food thus&#13;
will support the government program in reducing&#13;
stunting incidence in Indonesia. I would like to thank&#13;
Arindha Reni Pramesti, S.T., M.Sc, Azwien Niezam&#13;
Hawalie M., S.Tr.Kes, Muhammad Suhaeri, S.Si., M.Sc.,&#13;
Ph.D, and Prasandhya Astagiri Yusuf, S.Si, M.T, Ph.D as&#13;
a team in the Medical Technology Cluster, Indonesia</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
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                  <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11149">
                <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI &#13;
Evaluation of Anal Cytology and Human Papillomavirus Infection in High-Risk Women: A Cross-Sectional Study</text>
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          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11150">
                <text>anal neoplasms, cytology, human papillomavirus, Papanicolaou test,&#13;
uterine cervical neoplasms</text>
              </elementText>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11151">
                <text>BACKGROUND Anal cancer incidence has been on the rise over the past few decades.&#13;
This study aimed to assess anal Papanicolaou (Pap) smear changes in women with high&#13;
risk for dysplasia and human papillomavirus (HPV) infection.&#13;
METHODS This cross-sectional study was conducted in 121 patients referred to the&#13;
Gynecology Oncology Clinic of Imam Hossein Medical Center between 2020 and 2021 in&#13;
Tehran, Iran, who had cervical and vulvar dysplasia, cervical HPV infection, and abnormal&#13;
cervical cytology results and were over 21 years old. Data analysis was performed using&#13;
SPSS software version 21 (IBM Corp., USA) at a significance level of 0.05.&#13;
RESULTS 121 women, with a mean age of 39.69 years, were included in this study.&#13;
Overall, 23.1% of women had positive anal HPV results, and 35.5% were over 40 years&#13;
old. Younger age was associated with an increased risk of anal HPV (p = 0.045). 33.9%&#13;
of women were single and had a higher risk of anal HPV. Multiple sexual partnerships&#13;
and anal sex were the significant risk factors for anal cancer (p&lt;0.001). Women with&#13;
positive anal HPV results had significantly more genital warts (p&lt;0.001). No significant&#13;
difference was observed in smoking, educational level, and cervical Pap smear results&#13;
between women with negative and positive rectal HPV results.&#13;
CONCLUSIONS Younger age at diagnosis, being single, multiple sexual partnerships,&#13;
anal sex, and genital warts were associated with anal HPV infection in women.&#13;
Abnormal anal cytology was only associated with being single and having multiple&#13;
sexual partners.</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11152">
                <text>Tahereh Ashrafganjoei, Maryam Sadat Hosseini, Zanbagh Pirastehfar, Farah Farzaneh, Maliheh Arab, Noushin Afshar Moghaddam, Abdolreza Javadi, Ali Yaghobi Joybari</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="11153">
                <text>https://doi.org/10.13181/mji.oa.236375</text>
              </elementText>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11154">
                <text>March 10, 2023</text>
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          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11155">
                <text>peri irawan</text>
              </elementText>
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          <element elementId="42">
            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11156">
                <text>pdf</text>
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          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11157">
                <text>english</text>
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            <name>Type</name>
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            <elementTextContainer>
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      <tag tagId="691">
        <name>anal neoplasms</name>
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      <tag tagId="692">
        <name>cytology</name>
      </tag>
      <tag tagId="693">
        <name>human papillomavirus</name>
      </tag>
      <tag tagId="25">
        <name>Jurnal Internasional</name>
      </tag>
      <tag tagId="694">
        <name>Papanicolaou test</name>
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      <tag tagId="695">
        <name>uterine cervical neoplasms</name>
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          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="11073">
                  <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI</text>
                </elementText>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11189">
                <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI &#13;
Interferon-Gamma Release Assay and Chest X-Ray to Classify Intraocular Tuberculosis among Clinically Undifferentiated Uveitis </text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11190">
                <text>interferon-gamma release assay, tuberculosis, uveitis, X-ray</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11191">
                <text>BACKGROUND Tuberculosis (TB) is a common cause of intraocular inflammation in&#13;
Indonesia. As no accurate biomarker can confirm the diagnosis, ophthalmologists&#13;
often rely on systemic findings, such as tuberculin skin test, interferon-gamma release&#13;
assay (IGRA), and chest X-ray (CXR) for TB suspicion. This study aimed to evaluate IGRA&#13;
and CXR in classifying intraocular TB among patients with a clinically undifferentiated&#13;
cause of uveitis.&#13;
METHODS This cross-sectional study included 116 patients (a total of 163 affected eyes)&#13;
with a clinically undifferentiated cause of uveitis. IGRA and CXR were performed as&#13;
part of the workup. Data on visual acuity, anterior chamber inflammation grade, and&#13;
anatomical classification of uveitis were recorded. As there were no confirmed ocular&#13;
tuberculosis (OTB) in our cases, eyes were classified into probable OTB, possible OTB,&#13;
and unclassified.&#13;
RESULTS Overall, 93 patients (80.2%) with a clinically undifferentiated cause of uveitis&#13;
&#13;
had positive IGRA, whereas 10 (8.6%) had CXR results suggestive of TB. More than one-&#13;
third of the patients were blind (visual acuity &lt;3/60), and panuveitis was the commonest&#13;
&#13;
anatomical classification. A trend was identified in patients with panuveitis, who often&#13;
showed ≥2+ cell anterior chamber inflammation (p for trend = 0.023), according to&#13;
OTB criteria (probable OTB = 3/4, 75.0%; possible OTB = 44/67, 65.7%; unclassified =&#13;
2/9, 22.2%). Furthermore, the clinically undifferentiated uveitis cases were eligible to&#13;
be stratified into probable (8.6%) and possible (75.0%) OTB categories after IGRA and&#13;
CXR examinations.&#13;
CONCLUSIONS The combination of IGRA and CXR is valuable for classifying and&#13;
diagnosing TB-related uveitis. A multidisciplinary approach is essential when the cause&#13;
of uveitis is unknown.</text>
              </elementText>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11192">
                <text>Mei Riasanti, Ikhwanuliman Putera, Priscilla Jessica, Muhammad Zakiy Waliyuddin, Faiz Alwan Tagar, Andini Karlina CH, Yulia Aziza, Made Susiyanti, Lukman Edwar, Ratna Sitompul, Rina La Distia Nora</text>
              </elementText>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="11193">
                <text>https://doi.org/10.13181/mji.oa.226324</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11194">
                <text>October 18, 2022</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11195">
                <text>peri irawan</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="42">
            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
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              <elementText elementTextId="11196">
                <text>pdf</text>
              </elementText>
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          </element>
          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11197">
                <text>english</text>
              </elementText>
            </elementTextContainer>
          </element>
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              <elementText elementTextId="11198">
                <text>text</text>
              </elementText>
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          </element>
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    <tagContainer>
      <tag tagId="674">
        <name>interferon-gamma release assay</name>
      </tag>
      <tag tagId="25">
        <name>Jurnal Internasional</name>
      </tag>
      <tag tagId="166">
        <name>tuberculosis</name>
      </tag>
      <tag tagId="675">
        <name>uveitis</name>
      </tag>
      <tag tagId="676">
        <name>X-ray</name>
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          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="11073">
                  <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI</text>
                </elementText>
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    <elementSetContainer>
      <elementSet elementSetId="1">
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        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11159">
                <text>Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI &#13;
Pancreatoblastoma in Previously Pancreatic Pseudocysts in a 14-Year-Old Female: A Case Report </text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11160">
                <text>pancreas, pancreatic neoplasm, pancreatic pseudocysts,&#13;
pancreatoblastoma</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11161">
                <text>Pancreatoblastoma is a rare tumor characterized by uncontrolled growth of pancreatic&#13;
epithelial cells with a mix of squamous nests and acinar differentiation. Diagnostic&#13;
modalities include abnormal liver enzyme, pancreatic enzyme, and imaging findings.&#13;
Treatment options include surgical resection, sometimes combined with chemotherapy,&#13;
depending on the tumor’s size and grade. We reported a pancreatoblastoma in&#13;
a 14-year-old female with prior pancreatic pseudocysts. The transformation from&#13;
pseudocysts to pancreatoblastoma is believed to be caused by the heterozygosity&#13;
molecular loss on the 11p chromosome and several genetic mutations. Magnetic&#13;
resonance cholangiopancreatography showed a well-defined, heterogeneous mass in&#13;
the pancreatic head, with 70% of the mass composed of cysts. A partial pancreatectomy&#13;
was performed because a complete pancreatectomy may harm the adjacent structures.&#13;
However, a complete resection combined with chemoradiation may be the best option&#13;
for long-term survival and complete remission. In this case, she was disease-free until&#13;
30 months after the chemotherapy protocol.</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11162">
                <text>Monica Bellynda, Marsih, Yohanes Adinugroho, Suwardi, Muhammad Riza, Faizal Muhammad</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="11163">
                <text>https://doi.org/10.13181/mji.cr.236351</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11164">
                <text>February 13, 2023</text>
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            </elementTextContainer>
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          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11165">
                <text>peri irawan</text>
              </elementText>
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          <element elementId="42">
            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11166">
                <text>pdf</text>
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            </elementTextContainer>
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          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="11167">
                <text>english</text>
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    <tagContainer>
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        <name>Jurnal Internasional</name>
      </tag>
      <tag tagId="94">
        <name>pancreas</name>
      </tag>
      <tag tagId="688">
        <name>pancreatic neoplasm</name>
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      <tag tagId="689">
        <name>pancreatic pseudocysts</name>
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      <tag tagId="690">
        <name>pancreatoblastoma</name>
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  </item>
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