16 10 198 https://repository.horizon.ac.id/files/original/4e1ebe1cad30ee20b6bffe7b8877b36a.pdf b0256e51400deca078de51a2460b8d9c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Clinical significance of elevated D-dimer in emergency department patients: a retrospective single-center analysis Subject The topic of the resource D-dimer is a marker of coagulation and fibrinolysis widely used in clinical Description An account of the resource Abstract Introduction D-dimer is a marker of coagulation and fibrinolysis widely used in clinical practice for assessing thrombotic activity. While it is commonly ordered in the Emergency Department (ED) for suspected venous thromboembolism (VTE), elevated D-dimer levels can occur due to various other disorders. The aim of this study was to find out the causes of elevated D-dimer in patients presenting to a large ED in Saudi Arabia and evaluate the accuracy of D-dimer in diagnosing these conditions. Methods Data was collected from an electronic hospital information system of patients who visited the ED from January 2016 to December 2022. Demographic information, comorbidities, D-dimer levels, and diagnoses were analyzed. Statistical analysis was performed using the SPSS software. The different diagnoses associated with D-dimer levels were analyzed by plotting the median D-dimer levels for each diagnosis category and their interquartile ranges (IQR). The receiver operating characteristic (ROC) curves were calculated and their area under the curve (AUC) values were demonstrated. The optimal cut-off points for specific diseases were determined based on the ROC analysis, along with their corresponding sensitivities and specificities. Results A total of 19,258 patients with D-dimer results were included in the study. The mean age of the participants was 50 years with a standard deviation of ±18. Of the patients, 66% were female and 21.2% were aged 65 or above. Additionally, 21% had diabetes mellitus, 20.4% were hypertensive, and 15.1% had been diagnosed with dyslipidemia. The median D-dimer levels varied across different diagnoses, with the highest level observed in aortic aneurysm 5.46 g/L. Pulmonary embolism (PE) and deep vein thrombosis (DVT) were found in 729 patients (3.8%) of our study population and their median D-dimer levels 3.07 g/L (IQR: 1.35–7.05 g/L) and 3.36 g/L (IQR: 1.06–8.38 g/L) respectively. On the other hand, 1767 patients (9.2%) were diagnosed with respiratory infections and 936 patients (4.9%) were diagnosed with shortness of breath (not specified) with median D-dimer levels of 0.76 g/L (IQR: 0.40–1.47 g/L) and 0.51 g/L (IQR: 0.29–1.06 g/L), respectively. D-dimer levels showed superior or excellent discrimination for PE (AUC=0.844), leukemia (AUC=0.848), and aortic aneurysm (AUC=0.963). DVT and aortic dissection demonstrated acceptable discrimination, with AUC values of 0.795 and 0.737, respectively. D-dimer levels in respiratory infections and shortness of breath (not specified) exhibited poor to discriminatory performance. Creator An entity primarily responsible for making the resource Mohammed Alshalhoub1,2*, Faisal Alhusain1,2, Feras Alsulaiman1,2, Abdulaziz Alturki2,3, Saud Aldayel2,3 and Majid Alsalamah1,2,3 Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00620-6 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text D-dimer is a marker of coagulation and fibrinolysis widely used in clinical https://repository.horizon.ac.id/files/original/1876c21a8d8dc90ab43d3e762e10294e.pdf 2126946343b3521033a59a91b8b12b66 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Evaluation of elevated serum apelin-13 and D-dimer concentrations in individuals diagnosed with pulmonary embolism Subject The topic of the resource Pulmonary embolism, Thromboembolism, Apelin-13, D-dimer Description An account of the resource Abstract Background Given the limited specificity of D-dimer, there is a perceived need to discover a more precise marker for diagnosing individuals who are suspected of having pulmonary embolism (PE). In this study, by evaluating the increase in the serum level of Apelin-13 and D-dimer, we found valuable findings about Apelin-13, which can be suggested as an auxiliary and non-invasive diagnostic biomarker in individuals with suspected PE, based on the obtained results. Methods In this case-control study, 52 Iranian individuals were included, all of whom were suspected to have PE. These individuals were then divided into two groups based on the results of CT angiography, which is considered the gold standard imaging method for diagnosing PE. The two groups were patients with PE and patients without PE. Finally, the levels of certain markers in the serum were compared between the two groups. Results The mean serum D-dimer levels in patients with PE were significantly elevated (p<0.001) in comparison to those without PE (1102.47 to 456.2 ng/ml). Furthermore, the mean level of Apelin-13 was significantly higher in patients with PE (49.8 to 73.11 ng/L) (p<0.001). The cutoff point of Apelin-13 has been calculated at 58.50 ng/ml, with 90.9% sensitivity and 90% specificity. The D-dimer cutoff point was 500 ng/ml, with 95.5% sensitivity and 43.3% specificity. Conclusions Based on the results of this study, the serum level of Apelin-13 can be used as a novel diagnostic and screening biomarker in patients with pulmonary thromboembolism. Keywords Pulmonary embolism, Thromboembolism, Apelin-13, D-dimer Creator An entity primarily responsible for making the resource Alireza Mehrban1 , Fatemeh Ahmadi Hajikolaei2†, Mehdi Karimi3*†, Reza Khademi4 , Akram Ansari5 , Durdi Qujeq6 , Karimollah Hajian-Tilaki7 and Mahmood Monadi8,9* Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00619-z Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Pulmonary embolism, Thromboembolism, Apelin-13, D-dimer https://repository.horizon.ac.id/files/original/98895c2d7332364fc5a32eb320f8fb37.pdf 696f25e2782c5efaff58191d86a8ccd4 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A survivor with unexplained chest scars Subject The topic of the resource Cardiopulmonary resuscitation, Chest compression device, PICS (Post Intensive Care Syndrome), Keloid scar Description An account of the resource Abstract This case illustrates chest scars after piston-based chest compression device resuscitation and raises the awareness of the potential benefits of following up survivors of critical illness. Keywords Cardiopulmonary resuscitation, Chest compression device, PICS (Post Intensive Care Syndrome), Keloid scar Creator An entity primarily responsible for making the resource Viviane Donner1*, Mathieu Affaticati2 , Elodie Izydorczyk1 and Sara Cereghetti1 Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00618-0 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Cardiopulmonary resuscitation, Chest compression device, PICS (Post Intensive Care Syndrome), Keloid scar https://repository.horizon.ac.id/files/original/1afa1c7af96a8ba34e096284100139a0.pdf de3b05be95eb94b31a028111256ebc8a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Natto (fermented soybeans)-induced anaphylaxis in a surfer with the possibility of sensitization to poly(γ-glutamic acid) from cutaneous exposure to jellyfish sting: a case report Subject The topic of the resource Natto, Allergy, Poly(γ-glutamic acid), Jellyfish, Cutaneous exposure Description An account of the resource Abstract Background We report a case of anaphylaxis induced by natto (fermented soybeans) allergy that occurred following dermal sensitization from a jellyfish sting. Case presentation A 49-year-old male presented to the emergency room complaining of an acute onset of erythema with pruritis that appeared while he was surfing. Given that his heart rate dropped to ~40 bpm without a decline in blood pressure or oxygen saturation, we suspected anaphylaxis and administered 0.5 mg of adrenaline intramuscularly. Immediately after the muscular adrenaline injection, his heart rate recovered to ~60–70 bpm. Conclusions The major allergen that induces natto allergy is poly(γ-glutamic acid) (PGA), which is present in its mucilage. Given that PGA is also produced by jellyfish tentacles, it can be inferred that the PGA sensitization occurred via dermal exposure to jellyfish PGA. This is an example of a food allergy induced by animal stings. As PGA is a high- molecular-weight polymer, natto allergy, despite being IgE-mediated, often presents with late-onset anaphylaxis, which typically develops half a day after digestion. PGA has a wide range of applications in pharmaceuticals, cosmetics, and foods. Patients may develop allergic symptoms and experience repeated anaphylaxis with no known cause. Therefore, it is important to obtain a detailed medical history and individually instruct patients suspected of being allergic to PGA to avoid PGA-containing products. Keywords Natto, Allergy, Poly(γ-glutamic acid), Jellyfish, Cutaneous exposure Creator An entity primarily responsible for making the resource Ayami Shigeno1*, Tsuyoshi Suzuki2 , Masakazu Obayashi1 , Kei Asada1 and Satoru Matsushima1 Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00617-1 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Natto, Allergy, Poly(γ-glutamic acid), Jellyfish, Cutaneous exposure https://repository.horizon.ac.id/files/original/ab248c57df8a4a71de94c4127a6c28b7.pdf c14c35f69134a62d740216608ca4cb19 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Screening for harmful substance use in emergency departments: a systematic review Subject The topic of the resource Substance-related disorders, Drug abuse screening, Emergency, Departments, Public health Description An account of the resource Abstract Background Substance use-related emergency department (ED) visits have increased substantially in North Amer‐ ica. Screening for substance use in EDs is recommended; best approaches are unclear. This systematic review synthe‐ sizes evidence on diagnostic accuracy of ED screening tools to detect harmful substance use. Methods We included derivation or validation studies, with or without comparator, that included adult (≥18 years) ED patients and evaluated screening tools to identify general or specific substance use disorders or harmful use. Our search strategy combined concepts Emergency Department AND Screening AND Substance Use. Trained review‐ ers assessed title/abstracts and full-text articles for inclusion, extracted data, and assessed risk of bias (QUADAS-2) independently and in duplicate. Reviewers resolved disagreements by discussion. Primary investigators adjudicated if necessary. Heterogeneity precluded meta-analysis. We descriptively summarized results. Results Our search strategy yielded 2696 studies; we included 33. Twenty-one (64%) evaluated a North Ameri‐ can population. Fourteen (42%) applied screening among general ED patients. Screening tools were administered by research staff (n=21), self-administered by patients (n=10), or non-research healthcare providers (n=1). Most studies evaluated alcohol use screens (n=26), most commonly the Alcohol Use Disorders Identification Test (AUDIT; n=14), Cut down/Annoyed/Guilty/Eye-opener (CAGE; n=13), and Rapid Alcohol Problems Screen (RAPS/RAPS4/ RAPS4-QF; n=12). Four studies assessing six tools and screening thresholds for alcohol abuse/dependence in North American patients (AUDIT≥8; CAGE≥2; Diagnostic and Statistical Manual of Mental Disorders, 4th Edition [DSM- IV-2]≥1; RAPS≥1; National Institute on Alcohol Abuse and Alcoholism [NIAAA]; Tolerance/Worry/Eye-opener/ Amnesia/K-Cut down [TWEAK]≥3) reported both sensitivities and specificities≥83%. Two studies evaluating a single alcohol screening question (SASQ) (When was the last time you had more than X drinks in 1 day?, X=4 for women; X=5 for men) reported sensitivities 82–85% and specificities 70–77%. Five evaluated screening tools for general substance abuse/dependence (Relax/Alone/Friends/Family/Trouble [RAFFT]≥3, Drug Abuse Screening Test [DAST]≥4, single drug screening question, Alcohol, Smoking and Substance Involvement Screening Test [ASSIST]≥42/18), reporting sensitivities 64%-90% and specificities 61%-100%. Studies’ risk of bias were mostly high or uncertain. Conclusions Six screening tools demonstrated both sensitivities and specificities≥83% for detecting alcohol abuse/ dependence in EDs. Tools with the highest sensitivities (AUDIT≥8; RAPS≥1) and that prioritize simplicity and effi‐ ciency (SASQ) should be prioritized. Keywords Substance-related disorders, Drug abuse screening, Emergency, Departments, Public health Creator An entity primarily responsible for making the resource Jessica Moe1*, Justin Koh2 , Jennifer A. Ma3 , Lulu X. Pei1 , Eleanor MacLean1 , James Keech4 , Kaitlyn Maguire1 , Claire Ronsley1 , Mary M. Doyle‐Waters5 and Jeffrey R. Brubacher1 Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00616-2 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Substance-related disorders, Drug abuse screening, Emergency, Departments, Public health https://repository.horizon.ac.id/files/original/2a66d3152de2d91cf3525a40a9378195.pdf a0f18422be4108c566df4d729afcdadf Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Patient-controlled analgesia morphine for the management of acute pain in the emergency department: a systematic review and meta- analysis Subject The topic of the resource PCA morphine, IV morphine, Acute pain, Emergency department Description An account of the resource Abstract Background The ideal pain control approach is typically viewed as titration of analgesia for pain reduction and periodic pain evaluation. However, this method takes time and is not always possible in the crowded Emergency Department. Therefore, an alternative way to improve pain care in the Emergency Department is needed to avoid this unpleasant sensation in the patients. The best solution to tackle this situation is using Patient Controlled Analgesia (PCA), in the form of a PCA pump. Study objectives This systematic review and meta-analysis was designated to evaluate the efficacy of PCA morphine in treating acute pain at Emergency Department. Methods We searched databases Cochrane Central Register of Controlled Trials (CENTRAL), Medline, and Google Scholar up to February 2022 and identified randomized controlled trials with English language only that compare PCA morphine to IV morphine in treating patients presenting with acute pain at Emergency Department. Results Eight trials were included in our review, comprising 1490 participants. We compared PCA morphine vs. IV morphine. There were no differences in the pain score between PCA and IV morphine (standard mean difference [SMD] = -0.20, p=0.25). Further subgroup analyses (origin of the pain, time of assessment and the durations) showed no difference except for the dosages as the PCA morphine reduced the pain compared to IV morphine in low and high dosages but only two studies were involved. However, the analysis showed PCA morphine increased patient satisfaction and reduced the number of patients who required additional analgesia compared to IV morphine (MD 0.12, P<0.001), (MD 0.47, P<0.001) respectively. Data obtained in this review pertaining to adverse effects such as nausea, vomiting, pruritus, and drowsiness is limited since not all the trials reported the events. Conclusions PCA morphine do appear to have a beneficial effect on the outcome of patient satisfaction and the number of patients who required additional analgesia. However, further studies targeting a larger sample size is required to increase the certainty of the evidence. Creator An entity primarily responsible for making the resource Muhammad Baihaqi Oon1 , Nik Hisamuddin Nik Ab. Rahman1,3*, Norhayati Mohd Noor2 and Mohd Boniami Yazid1 Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00615-3 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text PCA morphine, IV morphine, Acute pain, Emergency department https://repository.horizon.ac.id/files/original/1f089d02d71a847985e7f240ceb6c99c.pdf 2ef0effd9acd0ec755de8ebbb8319ff8 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Utilizing the National Early Warning Score 2 (NEWS2) to confirm the impact of emergency department management in sepsis patients: a cohort study from taiwan 1998–2020 Subject The topic of the resource Hospital mortality, National early warning score 2 (NEWS2), Prediction score, Sepsis, Sequential organ failure assessment score (SOFA score) Description An account of the resource Abstract Background Most sepsis patients could potentially experience advantageous outcomes from targeted medical intervention, such as fluid resuscitation, antibiotic administration, respiratory support, and nursing care, promptly upon arrival at the emergency department (ED). Several scoring systems have been devised to predict hospital outcomes in sepsis patients, including the Sequential Organ Failure Assessment (SOFA) score. In contrast to prior research, our study introduces the novel approach of utilizing the National Early Warning Score 2 (NEWS2) as a means of assessing treatment efficacy and disease progression during an ED stay for sepsis. Objectives To evaluate the sepsis prognosis and effectiveness of treatment administered during ED admission in reducing overall hospital mortality rates resulting from sepsis, as measured by the NEWS2. Methods The present investigation was conducted at a medical center from 1997 to 2020. The NEWS2 was calculated for patients with sepsis who were admitted to the ED in a consecutive manner. The computation was based on the initial and final parameters that were obtained during their stay in the ED. The alteration in the NEWS2 from the initial to the final measurements was utilized to evaluate the benefit of ED management to the hospital outcome of sepsis. Univariate and multivariate Cox regression analyses were performed, encompassing all clinically significant variables, to evaluate the adjusted hazard ratio (HR) for total hospital mortality in sepsis patients with reduced severity, measured by NEWS2 score difference, with a 95% confidence interval (adjusted HR with 95% CI). The study employed Kaplan-Meier analysis with a Log-rank test to assess variations in overall hospital mortality rates between two groups: the “improvement (reduced NEWS2)” and “non-improvement (no change or increased NEWS2)” groups. Results The present investigation recruited a cohort of 11,011 individuals who experienced the first occurrence of sepsis as the primary diagnosis while hospitalized. The mean age of the improvement and non-improvement groups were 69.57 (±16.19) and 68.82 (±16.63) years, respectively. The mean SOFA score of the improvement and non-improvement groups were of no remarkable difference, 9.7 (±3.39) and 9.8 (±3.38) years, respectively. The total hospital mortality for sepsis was 42.92% (4,727/11,011). Following treatment by the prevailing guidelines at that time, a total of 5,598 out of 11,011 patients (50.88%) demonstrated improvement in the NEWS2, while the remaining 5,403 patients (49.12%) did not. The improvement group had a total hospital mortality rate of 38.51%, while the non-improvement group had a higher rate of 47.58%. The non-improvement group exhibited a lower prevalence of comorbidities such as congestive heart failure, cerebral vascular disease, and renal disease. The non-improvement group exhibited a lower Charlson comorbidity index score [4.73 (±3.34)] compared to the improvement group [4.82 (±3.38)] The group that underwent improvement exhibited a comparatively lower incidence of septic shock development in contrast to the non-improvement group (51.13% versus 54.34%, P<0.001). The improvement group saw a total of 2,150 patients, which represents 38.41% of the overall sample size of 5,598, transition from the higher-risk to the medium-risk category. A total of 2,741 individuals, representing 48.96% of the sample size of 5,598 patients, exhibited a reduction in severity score only without risk category alteration. Out of the 5,403 patients (the non-improvement group) included in the study, 78.57% (4,245) demonstrated no alteration in the NEWS2. Conversely, 21.43% (1,158) of patients exhibited an escalation in severity score. The Cox regression analysis demonstrated that the implementation of interventions aimed at reducing the NEWS2 during a patient’s stay in the ED had a significant positive impact on the outcome, as evidenced by the adjusted HRs of 0.889 (95% CI=0.808, 0.978) and 0.891 (95% CI=0.810, 0.981), respectively. The results obtained from the Kaplan-Meier analysis indicated that the survival rate of the improvement group was significantly higher than that of the non-improvement group (P<0.001) in the hospitalization period. Conclusion The present study demonstrated that 50.88% of sepsis patients obtained improvement in ED, ascertained by means of the NEWS2 scoring system. The practical dynamics of NEWS2 could be utilized to depict such intricacies clearly. The findings also literally supported the importance of ED management in the comprehensive course of sepsis treatment in reducing the total hospital mortality rate. Keywords Hospital mortality, National early warning score 2 (NEWS2), Prediction score, Sepsis, Sequential organ failure assessment score (SOFA score) Creator An entity primarily responsible for making the resource Ming-Shun Hsieh1,2,3,4, Kuan-Chih Chiu5 , Amrita Chattopadhyay5 , Tzu-Pin Lu5 , Shu-Hui Liao6 , Chia-Ming Chang2,3, Yi-Chen Lee1 , Wei-En Lo1 , Vivian Chia-Rong Hsieh7 , Sung-Yuan Hu4,8,9,3† and Chorng-Kuang How2,3*† Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00614-4 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Hospital mortality, National early warning score 2 (NEWS2) https://repository.horizon.ac.id/files/original/b1bcd35457df7df6f56186eb8e808544.pdf aa1623107e995e949812faafd0cb42e5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A case report of an accidental iatrogenic dexmedetomidine overdose in an adult Subject The topic of the resource Alpha2-agonists, Medication error, Adverse effect, Oversedation, Case report Description An account of the resource Abstract Background Dexmedetomidine is a sedative drug with a wide safety margin. Case presentation We present a case of accidental iatrogenic dexmedetomidine overdose in an adult patient during high-intensity focused ultrasound (HIFU) treatment. This is the first case report of an adult patient receiving an intravenous push of dexmedetomidine. Overdose resulted in severe oversedation, but symptoms receded spontaneously over time. Conclusions Dexmedetomidine overdoses are infrequent, and they are usually the result of an administration error. Keywords Alpha2-agonists, Medication error, Adverse effect, Oversedation, Case report Creator An entity primarily responsible for making the resource Suvi-Maria Tiainen1,2,3, Jonni Unga4 and Panu Uusalo1,2* Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00613-5 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Alpha2-agonists, Medication error, Adverse effect, Oversedation, Case report https://repository.horizon.ac.id/files/original/b642acbc844bce555eeb56e9af322cf2.pdf 4157dcf8fb5d9e2fba32db6e062adb5f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Jejunogastric intussusception associated with jejunojejunal intussusception (double telescoping) occurring 20 years after gastrojejunostomy Subject The topic of the resource Gastrojejunostomy, Jejunogastric intussusception, Case report Description An account of the resource Abstract Introduction Jejunogastric intussusception (JGI) is a rare but potentially lethal complication following gastrectomy or gastrojejunostomy surgeries. Diagnosis of this condition can be challenging due to its rarity and non-specific symp- toms. This article presents a case report of a 60-year-old male with a history of trans mesocolic gastrojejunostomy who developed acute symptoms of JGI. Case report The patient presented with acute epigastric pain, vomiting, and hematemesis. Physical examination and laboratory tests indicated dehydration, tachycardia, and leukocytosis. Computed tomography (CT) revealed intus- suscepted loops within the stomach. Emergency laparotomy was performed, and the intussusception was manually reduced without the need for resection. The patient recovered well and was discharged five days post-surgery. Discussion Retrograde jejunogastric intussusception is a rare complication, often occurring years after gastric surgery. It can be classified into acute and chronic forms, with the former presenting with intense pain and potential hematemesis. The condition can arise in different surgical contexts and even spontaneously. The cause of JGI remains unclear, but factors such as hyperacidity, abnormal motility, and increased intra-abdominal pressure have been impli- cated. Diagnosis can be made through endoscopy or alternative imaging modalities such as CT. Surgical intervention is the treatment of choice, with various options available based on intraoperative findings. Conclusion Retrograde jejunogastric intussusception is challenging to diagnose and treat due to its rarity and lack of understanding of its causes. Imaging techniques and endoscopy play important roles in diagnosis, while surgery remains the primary treatment option. Vigilance is necessary among medical professionals to consider JGI in cases of acute abdominal pain and vomiting following gastric surgery, allowing for prompt diagnosis and intervention to prevent bowel necrosis. Further research is needed to establish optimal surgical strategies and evaluate recurrence rates. Keywords Gastrojejunostomy, Jejunogastric intussusception, Case report Creator An entity primarily responsible for making the resource Souhaib Atri1 , Mahdi Hammami1*, Amine Sebai1 , Rany Aifia1 , Meriem Ben Brahim1 , Youssef Chaker1 , Fadhel Samir Fteriche1 and Montassar Kacem1 Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00612-6 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Gastrojejunostomy, Jejunogastric intussusception, Case report https://repository.horizon.ac.id/files/original/30fcb794b0cfcee5c5623bb4bf964454.pdf 30f42552e857e119cb89518d13a2c486 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Impact of teaching on use of mechanical chest compression devices: a simulation- based trial Subject The topic of the resource Cardiopulmonary resuscitation, Mechanical chest compression devices, Medical education, Simulation Description An account of the resource Background The use of mechanical chest compression devices on patients in cardiac arrest has not shown benefits in previous trials. This is surprising, given that these devices can deliver consistently high-quality chest compressions without interruption. It is possible that this discrepancy is due to the no-flow time (NFT) during the application of the device. In this study, we aimed to demonstrate a reduction in no-flow time during cardiopulmonary resuscitation (CPR) with mechanical chest compression devices following 10 min of structured training in novices. Methods 270 medical students were recruited for the study. The participants were divided as a convenience sample into two groups. Both groups were instructed in how to use the device according to the manufacturer’s specifications. The control group trained in teams of three, according to their own needs, to familiarise themselves with the device. The intervention group received 10 min of structured team training, also in teams of three. The participants then had to go through a CPR scenario in an ad-hoc team of three, in order to evaluate the training effect. Results The median NFT was 26.0 s (IQR: 20.0–30.0) in the intervention group and 37.0 s (IQR: 29.0–42.0) in the control group (p<0.001). In a follow-up examination of the intervention group four months after the training, the NFT was 34.5 s (IQR: 24.0–45.8). This represented a significant deterioration (p=0.015) and was at the same level as the control group immediately after training (p=0.650). The position of the compression stamp did not differ significantly between the groups. Groups that lifted the manikin to position the backboard achieved an NFT of 35.0 s (IQR: 27.5–42.0), compared to 41.0 s (IQR: 36.5–50.5) for the groups that turned the manikin to the side (p=0.074). Conclusions This simulation-based study demonstrated that structured training can significantly reduce the no-flow time when using mechanical resuscitation devices, even in ad-hoc teams. However, this benefit seems to be short- lived: after four months no effect could be detected. Keywords Cardiopulmonary resuscitation, Mechanical chest compression devices, Medical education, Simulation Creator An entity primarily responsible for making the resource Richard Steffen1 , Simon Burri1 , Fredy-Michel Roten1,3, Markus Huber1 and Jürgen Knapp1,2* Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00611-7 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Cardiopulmonary resuscitation, Mechanical chest compression devices, Medical education, Simulation