7 10 198 https://repository.horizon.ac.id/files/original/b4bfda8dcb90edf439cbf97ca17a4d64.pdf a19f60aafacc02a1f151c8816ca81c2a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A 26 years old primigravida woman presented with abdominal cutaneous entrapment syndrome: a case report Subject The topic of the resource ACNES, Neuropathic pain, Pregnancy Description An account of the resource Abstract Background Abdominal cutaneous nerve entrapment syndrome (ACNES) is characterized by severe, mostly refractory, chronic pain due to the entrapment of the cutaneous branches of the lower torso intercostal nerves at the lateral edge of the rectus abdominis muscle. ACNES is rare compared to other pregnancy-related peripheral neuropathies and is often overlooked as a differential diagnosis for abdominal pain, despite the diagnosis relying primarily on patient history and physical examination. Emergency physicians and other medical personnel’s lack of exposure to such cases results in unnecessary laboratory requests, repeated visits, and increased fear and tension for the patient. Case presentation A 26-year-old primigravida on her second trimester of pregnancy presented to our Emergency department with persistent localized right upper quadrant abdominal pain. Despite repeated visit to the nearby hospital, no diagnosis was settled and the pain persisted. At our ED after a thorough history, physical examination and diagnostic test no abnormality was found. Finally Abdominal cutaneous nerve entrapment syndrome (ACNES) was considered and a mixture of 1 ml 2% lidocaine with adrenaline and 1 ml dexamethasone (4 mg) was infiltrated into the fascial plane in a fanning fashion into the most tender area using a modified technique and the patient reported significant improvement in pain. Conclusion Abdominal cutaneous nerve entrapment syndrome (ACNES) is a cause of abdominal pain in pregnancy that is often overlooked. The objective of this study is to describe a rare case of ACNES in a 26-year-old primigravida woman who presented to a low-resource emergency department to assist patient management. Keywords ACNES, Neuropathic pain, Pregnancy Creator An entity primarily responsible for making the resource Melaku Tsediew Berhanu1 , Molla Asnake Kebede2*, Adamu Tigabu Tessfaw3 , Alemayehu Beharu Tekle1 , Anteneh Messele Birhanu1 and Meron Teka Deresa4 Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00720-3 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text ACNES, Neuropathic pain, Pregnancy https://repository.horizon.ac.id/files/original/a7cee25afe7a5063f47a10d8885cef93.pdf adc2ef32b3797e0775addc0ed4b660f3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Demographics and scope of Australian emergency department physiotherapists Subject The topic of the resource Physiotherapy, Emergency department, Emergency physiotherapist Description An account of the resource Abstract Questions To provide workforce data on the status of Australian Emergency Department (ED) physiotherapy practice, including physiotherapist demographic data, staffing levels and funding sources. Evaluate the scope of practice currently undertaken by ED physiotherapists and alignment of ED physiotherapy service provision with demand levels. Design Cross sectional survey. Participants Australian physiotherapists working within an Australian ED. Outcome measures Workforce data, scope of practice and alignment of physiotherapy service provision to ED presentations and demand. Results 94 Australian ED physiotherapists completed the survey, 76.9% were working as primary contact clinicians. They had a diverse scope of practice, 100% perform mobility assessments, 89.9% provide care for paediatric patients and 10.1% were involved in administration of medications. 86.2% of participants (75/87) reported working within a service model that provided seven-day per week physiotherapy coverage to ED. Conclusion The sample of ED physiotherapists were found to be experienced and highly trained clinicians with a diverse scope of practice, who are well placed to meet the unpredictable and highly variable patient caseload of Australian EDs. Significance What this study adds This study expands on current literature which suggests a much narrower scope of Australian ED physiotherapists. The study demonstrates the full capabilities and scope of ED physiotherapists, and potentially lead to a better understanding amongst the wider healthcare population and greater utilisation of physiotherapists in ED. Keywords Physiotherapy, Emergency department, Emergency physiotherapist Creator An entity primarily responsible for making the resource Tina Vickery1*, Lindsey Brett2 and Taryn Jones3 Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00719-w Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Physiotherapy, Emergency department, Emergency physiotherapist https://repository.horizon.ac.id/files/original/e9e8c7ddfa4ca61c4bb54a7b4b9fd540.pdf f9529eeff86e7b864914d46ddd7ee181 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Anaphylactic reaction to tranexamic acid infusion in a six‐year‐old child: a case report Subject The topic of the resource Allergy, Anaphylaxis, Case report, Critical care, Pediatrics, Tranexamic acid Description An account of the resource Abstract Background Tranexamic acid (TXA) is commonly considered a safe drug to mitigate bleeding during and after vari- ous surgical settings among adults and children. In recent decades, anaphylaxis induced by TXA has been increasingly reported in adults. However, among pediatrics, there are fewer reported cases. Case presentation We report a case of a 6-year-old female who experienced anaphylaxis after receiving intravenous TXA following unilateral cleft lip and palate repair surgery. She exhibited clinical symptoms involving the cardio- vascular system, respiratory system, and skin. Following the administration of epinephrine, corticosteroid, and anti- histamine, the patient’s symptoms were relieved. A few months after discharge, an intradermal test, yielded a positive result, confirming TXA as the culprit drug. Conclusion Our report emphasizes the importance of considering anaphylaxis as a potential adverse reaction to TXA in pediatric patients, showing the criticality of rapid diagnosis and appropriate management for a successful outcome. Keywords Allergy, Anaphylaxis, Case report, Critical care, Pediatrics, Tranexamic acid Creator An entity primarily responsible for making the resource Nazanin Zibanejad1,2†, Nikta Nouri3† and Sharareh Babaie1,2* Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00718-x Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Allergy, Anaphylaxis, Case report, Critical care, Pediatrics, Tranexamic acid https://repository.horizon.ac.id/files/original/15e079a7a5e7e53645deb61591accf59.pdf e1c8343f7ca147f112193115e0a7e175 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Recruitment of emergency department patients to a prospective observational study Subject The topic of the resource Feasibility, Recruitment, Emergency research, Hypertension, Prospective observational, Asymptomatic hypertension, Racial and ethnic diversity, Diversity, Health equity Description An account of the resource Abstract Background The dynamic environment of the emergency department (ED) poses unique challenges to the execution of well-designed research. There is limited investigation into the viability of studies conducted in the ED. This paper offers a systematic evaluation of our recruitment of emergency patients for a prospective observational research study, shedding light on the intricate landscape of research feasibility within the ED setting. Results Research coordinators dedicated 2816.83 h to screening, recruiting, and enrolling patients between June 2018 and September 2023, having to stop recruitment twice due to financial constraints and the COVID-19 pandemic. 485 patients were approached and 84 of them were enrolled, resulting in a 31.94% enrollment rate, with approximately 2.8 participants recruited per month. Of those enrolled, 77 completed all study endpoints. Most participants were Hispanic (n=44; 52.3%) and/or Black (n=37; 44%), middle-aged (μ=51.7 years), and female (n=48; 57.1%). Participant recruitment was challenged by competing mindsets, the COVID-19 pandemic, and high staff turnover. Conclusions Recruiting emergency patients for a prospective observational study is feasible given adequate staffing and financial resources. Standardizing feasibility assessments for the recruitment of patients in the emergency department is important to the success of future study. Keywords Feasibility, Recruitment, Emergency research, Hypertension, Prospective observational, Asymptomatic hypertension, Racial and ethnic diversity, Diversity, Health equity Creator An entity primarily responsible for making the resource Claire Shubeck8 , Hans Reyes Garay4 , Bret P. Nelson1 , Marcee Wilder1,2,5, Aleksandra Degtyar1 , Megan Lukas1 , Lauren Gordon1,2,5, George T. Loo1,5, Bernice Coleman6 , Lynne D. Richardson1,2,5,7 and Kimberly Souffront1,2,3* Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00717-y Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Feasibility, Recruitment, Emergency research https://repository.horizon.ac.id/files/original/f710f79dbcf7da6bfe7e1f167f1d315a.pdf 7b33babcfe59d9eb31a63d55e854def9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Utility of smart watch in expediting diagnosis of cold drink-triggered atrial fibrillation: a case report Subject The topic of the resource Atrial fibrillation, Paroxysmal tachycardia, Emergency medicine, Electrocardiography, Precipitating factors, Palpitations, Cold drink, Smart watch Description An account of the resource Abstract Background Patients presenting to the emergency department with recent palpitations are a diagnostic challenge when the arrhythmia and its symptoms have resolved prior to arrival. Newer smart watch technology, adept at detecting atrial fibrillation, can assist in the diagnostic evaluation of transitory palpitations. We report a case of cold drink-triggered atrial fibrillation whose diagnosis would not have been possible without the assistance of the patient’s smart watch. Case presentation A middle-aged man without cardiac history developed sudden rapid, irregular palpitations with shortness of breath while drinking a glass of cold juice. He activated his smart watch with 1-lead electrocardiography technology which detected rapid atrial fibrillation. He sought medical care, but while waiting, his symptoms—then 90 min in duration—spontaneously resolved. His initial diagnostic evaluation documented only sinus rhythm, as did several follow-up evaluations with cardiology the next several weeks. Had it not been for his smart watch, the etiology of his transitory palpitations would have remained undiagnosed. His physicians encouraged trigger avoidance. In the following months, he avoided rapid ingestion of cold drink, taking instead small sips. The atrial fibrillation has not recurred. Conclusions The case illustrates the valuable contribution of smart watch technology in the diagnostic evaluation of patients with short-lived palpitations. The case also educates clinicians about cold drink and food as a trigger of paroxysmal atrial fibrillation. This trigger, like alcohol, can be modified. Cold drink trigger avoidance has been reported by patients to reduce atrial fibrillation recurrence and is a low-risk, cost-effective strategy that is often successful. Keywords Atrial fibrillation, Paroxysmal tachycardia, Emergency medicine, Electrocardiography, Precipitating factors, Palpitations, Cold drink, Smart watch Creator An entity primarily responsible for making the resource Grace V. Heringer1 and David R. Vinson2,3,4* Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00716-z Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Atrial fibrillation, Paroxysmal tachycardia https://repository.horizon.ac.id/files/original/2039fb1fa43dd05957592328c50d2df7.pdf f1abb9c35ee52325176b933db98710a3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Characteristics and outcomes of emergency department patients across health care systems: an international multicenter cohort study Subject The topic of the resource Emergency department, Health-care systems, Quality of care, Template for uniform reporting Description An account of the resource Abstract Background A wide variation of emergency medical system configurations across countries has limited the value of comparison of quality and performance measures in the past. Furthermore, lack of quantitative data on EDs pre- vents definition of the problems and possibilities for data driven improvement of quality of care. Therefore, the objec- tive is to describe and compare Emergency Department (ED) populations and characteristics, and their outcomes in the Netherlands, Denmark and Australia, using a recently developed template for uniform reporting of standard- ized measuring and describing of care provided in the ED (structure, staffing and governance, population, process times and outcomes). Methods This international multicenter cohort included all consecutive ED visits from National Quality Registries or Databases from participating sites from three countries. Patient and ED characteristics (using the template for uni- form reporting) and relevant clinical outcomes were described and compared per country. Results We included 212,515 ED visits in the Netherlands, 408,673 in Denmark and 556,652 in Australia. Patient characteristics differed markedly, with Australian ED patients being younger, less often triaged as“immediate”, and less often triaged with the high-risk chief complaints “feeling unwell” compared to Danish and Dutch patients. ED characteristics mainly differed with respect to the mean annual census per ED (Netherlands 26,738 (SD 2630), Denmark 36,675 (SD 12974), Australia 50,712 (4884)), median (IQR) lengths of stay of patients discharged home (Netherlands 2.1 (1.4–3.1); Denmark 2.8 (1.7–5.0); Australia 3.3 (2.0–5.0) hrs) and proportion of hospitalizations (ranging from 30.6 to 39.8%). In-hospital mortality was 4.0% in Australia, higher compared to the Netherlands and Denmark (both 1.6%). Not all indicators of the framework were available in all registries. Conclusions Patient and ED characteristics and outcomes varied largely across countries. Meaningful interpreta- tion of outcome differences across countries could be improved if quality registries would more consistently register the measures of the recently developed template for uniform reporting. Keywords Emergency department, Health-care systems, Quality of care, Template for uniform reporting Creator An entity primarily responsible for making the resource Bas de Groot1,2*, Nicoline T. C. Meijs3 , Michelle Moscova4 , Wouter Raven3 , Menno I. Gaakeer5 , Wendy A. M. H. Thijssen6 , Heleen Lameijer7 , Amith Shetty8 and Annmarie T. Lassen9 Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00715-0 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Emergency department, Health-care systems, Quality of care, Template for uniform reporting https://repository.horizon.ac.id/files/original/6e950d8094d223225443161594664ad4.pdf e35adee9e3fff0ac6adae2d9f285aba7 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Emergency department physiotherapists: consideration of perceived barriers and facilitators to help optimise their role in the Australian emergency department Subject The topic of the resource Physiotherapy, Emergency department, Emergency physiotherapist Description An account of the resource Abstract Questions What are the current barriers and facilitators to the role of ED physiotherapists? How do ED physiotherapists believe their role may be optimised within the context of the ED? Design Mixed methods study using a cross sectional survey. Participants Australian physiotherapists currently providing services to patients within an Australian emergency department. Intervention N/A. Outcome measures The survey included questions related to the level of integration of ED physiotherapy into emergency department teams and wider health system, and open answer questions to identify the factors which impact and influence ED physiotherapy practice, and the future of ED physiotherapy. Results 1 - Organisational culture, 2 - training and credentialling, 3 - governance, legislation and policies, 4 - funding, and 5 - advocacy and research were the five major themes generated from participant comments on existing facilitators and barriers to their role and the role of ED physiotherapists nationally. Six themes were generated from participant comments regarding the strategies to overcome barriers and facilitate an increased contribution by ED physiotherapists in the future: 1 - Training opportunities and specialisation pathways, 2 - Organisational culture, 3 - Governance, legislation and policies, 4 - Funding, 5 - Advocacy, 6 - Medicolegal Risks. Conclusion Australian emergency department physiotherapists perceive their roles and emergency physiotherapy service provision to be impacted by complex and multi-factorial influences. The overall contribution of ED physiotherapy is susceptible to influence from non-linear interactions of various agents and factors which span all levels of the health system. Trial registration N/A. Key Messages What was already known on this topic Very little was previously known regarding the perceptions of ED physiotherapists and how to increase their contribution to emergency department care. ED staff understanding of ED physiotherapy role was previously identified as the main barrier to the ED physiotherapist’s role. What this study adds This study demonstrated and details the complex and multifactorial influences which are perceived to impact ED physiotherapists currently and into the future. This research may be used to better inform healthcare redesign and innovation to improve ED physiotherapist’s ability to respond to ED workforce shortages and increased demand. Keywords Physiotherapy, Emergency department, Emergency physiotherapist Creator An entity primarily responsible for making the resource Tina Vickery1*, Lindsey Brett2 and Taryn Jones3 Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00714-1 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Physiotherapy, Emergency department, Emergency physiotherapist https://repository.horizon.ac.id/files/original/f2ed38dcdde638cf0a45cc1901e9f9eb.pdf 47dbd181a14ec24f2c33d4638354cfff Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Impact of advanced trauma life support training on 30-day mortality in severely injured patients at a Kenyan tertiary center: a retrospective matched case-control study Subject The topic of the resource Trauma is a leading cause of mortality worldwide, Description An account of the resource Abstract Introduction Trauma is a leading cause of mortality worldwide, particularly in low and middle-income countries (LMICs) like Kenya. This study evaluates the impact of Advanced Trauma Life Support (ATLS) training on 30-day mortality outcomes in severely injured patients at a tertiary care center in Kenya. Methods A retrospective matched case-control study was conducted at Aga Khan University Hospital, Nairobi. The study included adult patients (≥18 years) with polytrauma (Injury Severity Score [ISS]>15) from 2011 to 2022. Propensity score matching was used to pair 81 post-ATLS cases with 81 pre-ATLS controls based on age and ISS. Data analysis was performed using R Statistical language (version 4.3.0). Results The 30-day mortality rate decreased significantly from 17% (95% CI: 9.4–27.4%) pre-ATLS to 6% (95% CI: 2.0-13.5%) post-ATLS (p=0.028). No significant differences were found in baseline characteristics between the two groups. Road traffic accidents were the primary cause of trauma in both groups (72% pre-ATLS vs. 78% post-ATLS). Conclusion ATLS training significantly reduced 30-day mortality in severely injured patients, demonstrating its effectiveness even in resource-limited settings. Further prospective randomized studies are recommended to confirm these findings and evaluate long-term outcomes. Creator An entity primarily responsible for making the resource Charbel Kamau1 , Idris Chikophe2 , Abdulkarim Abdallah1 and Edwin Mogere1* Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00713-2 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Trauma is a leading cause of mortality worldwide, https://repository.horizon.ac.id/files/original/5ed687c92fc190c4d81e6f337b25061b.pdf 6205652aaf915b58d1757ce199b7003c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A case of convexity non‐aneurysmal subarachnoid hemorrhage caused by cerebral sinus thrombosis Subject The topic of the resource Subarachnoid hemorrhage, Cerebral sinus thrombosis, Case report, Convexity SAH Description An account of the resource Abstract Background Convexity subarachnoid hemorrhage (cSAH) is an uncommon presentation of subarachnoid bleeding, referring to bleeding more localized to the convexities of the brain. The diagnosis of cerebral venous sinus thrombo- sis (CVST) can be difficult especially when patients initially present with cSAH. The authors present a case and then discuss the pathophysiology and management. Case presentation A 56-year-old woman with a previous history of hypertension and ischemic heart disease pre- sented to the emergency department after experiencing it. Two seizures following a severe headache. The patient’s history was negative for recent illnesses, head trauma, history of migraines, smoking, alcohol consumption, or intra- venous drug use. The patient was diagnosed with CVST based on magnetic resonance venography (MRV). Genetic studies further identified homozygous mutations in the Prothrombin and MTHFR genes. Anticoagulant therapy was initiated with 60 mg of Enoxaparin twice daily and subsequently transitioned to Warfarin after 48 h continued for 3 months, and then replaced by rivaroxaban. Conclusions This study highlights the importance of considering CVST as a cause of SAH, emphasizes the role of advanced imaging in diagnosis, and demonstrates a successful treatment approach using both traditional and direct oral anticoagulants. The insights provided in this article can contribute to improving the management of patients with CVST-related SAH. Keywords Subarachnoid hemorrhage, Cerebral sinus thrombosis, Case report, Convexity SAH Creator An entity primarily responsible for making the resource Ali Abasi1 , Asra Moradkhani1 , Shiva Rahimi2 and Hannah Magrouni2* Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00712-3 Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Subarachnoid hemorrhage, Cerebral sinus thrombosis, Case report, Convexity SAH https://repository.horizon.ac.id/files/original/4c607f665f01a43ba2c36ef156b6b89d.pdf f178a751ed48975086b9863dccbd227a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Volume 17 Issue 1 2024 Contributor An entity responsible for making contributions to the resource peri irawan Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Posterior reversible encephalopathy syndrome (PRES) on the second postpartum day: learning experience from a case report and literature review Subject The topic of the resource Mild traumatic brain injury, Biomarkers, Head CT scan, Patient treatment turnaround time, Diagnostic accuracy Description An account of the resource Introduction Mild traumatic brain injury (mTBI) represents a major public health concern and affects millions of people worldwide every year. Diagnosis mainly relies on clinical criteria and computed tomography (CT) scans. GFAP (glial fibrillary acidic protein) and UCH-L1 (ubiquitin carboxyl-terminal hydrolase-L1) have been recently studied as potential biomarkers of mTBI. This study retrospectively evaluated the possible use of these combined biomarkers as negative predictors for excluding brain injuries in patients with suspected mTBI in the emergency department. Methods Adult patients (n=130) enrolled at Tor Vergata University Hospital (Rome, Italy), consecutively registered at the triage of the emergency department between October 2022 and January 2023, with non-penetrating TBI and Glasgow Coma Scale (GCS) score of 13–15, were considered. All eligible patients underwent intracranial CT scans and blood tests, within 12 h after trauma, for GFAP and UCH-L1 serum concentrations. Results Intracranial CT detected injuries in only seven patients (5%); GFAP and UCH-L1 tested positive in 96 patients and negative in 34 patients (74% vs. 26%). Combined biomarkers had a sensitivity equal to 1.00 (95% CI 0.64-1.00) and a negative predictive value (NPV) of 1.00 (0.99-1.00) in mTBI diagnosis with a negative CT. Conclusions Combined laboratory tests for GFAP and UCH-L1 biomarkers might play a potential clinical role in avoiding unnecessary head CT scans after mTBI in emergency departments. Keywords Mild traumatic brain injury, Biomarkers, Head CT scan, Patient treatment turnaround time, Diagnostic accuracy Creator An entity primarily responsible for making the resource Jacopo M. Legramante1,2†, Marilena Minieri1,3,4*†, Marzia Belli2 , Alfredo Giovannelli4 , Alessia Agnoli4 , Daniela Bajo4 , Lorenza Bellincampi4 , Anna Maria De Angelis4 , Alessandro Terrinoni3,4, Massimo Pieri3,4, Eleonora Nicolai3 , Vito N. Di Lecce2 , Carla Paganelli2 , Gianluigi Ferrazza1,2, Susanna Longo1,2, Marco Ciotti4 and Sergio Bernardini3,4 Source A related resource from which the described resource is derived https://doi.org/10.1186/s12245-024-00708-z Date A point or period of time associated with an event in the lifecycle of the resource 2024 Contributor An entity responsible for making contributions to the resource Peri Irawan Format The file format, physical medium, or dimensions of the resource pdf Language A language of the resource english Type The nature or genre of the resource text Mild traumatic brain injury, Biomarkers, Head CT scan, Patient treatment turnaround time, Diagnostic accuracy