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              <name>Title</name>
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                  <text>Volume 17 Issue 1 2024</text>
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              <name>Contributor</name>
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                  <text>peri irawan</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="132631">
                <text>The Addis Ababa toxicology curriculum&#13;
project: educational needs assessment&#13;
for the toxicology modules of an emergency&#13;
medicine training program</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Toxicology, Emergency medicine training, Curriculum, Sub-specialty</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="132633">
                <text>Abstract&#13;
Background The Toronto Addis Ababa Academic Collaboration in Emergency Medicine (TAAAC-EM) is a&#13;
bi-institutional partnership between the University of Toronto (UofT) and Addis Ababa University (AAU) focused on&#13;
addressing the need for emergency medicine (EM) postgraduate training and care in Ethiopia. Toxicology is a key&#13;
competency in EM. EM physicians are often the first and sole clinicians to identify and treat patients presenting with&#13;
a wide range of intoxications. The goal of this project was to conduct an educational needs assessment to inform the&#13;
development of a context-specific toxicology curriculum for the AAU EM training program.&#13;
Methods Our needs assessment employed a survey (available electronically and in paper format) and face-to-face&#13;
interviews conducted with Ethiopian EM faculty (all graduates of the AAU EM residency training program) and current&#13;
AAU EM residents. The survey was distributed in October 2018 and the interviews were conducted in November 2018.&#13;
Results Of the 63 surveys distributed, we received 17 complete responses and completed 11 interviews with AAU&#13;
EM faculty and residents. The survey conducted on toxicology training highlighted overall satisfaction with current&#13;
training, with thematic analysis revealing key areas for growth. System-related themes focused on resource availability,&#13;
healthcare access, and public health education. Provider-related themes emphasized the need for context-specific&#13;
training, including common local toxins, and for advanced toxicology training such as poison center rotations.&#13;
Patient-related themes centered on specific toxicological presentations in Ethiopia, highlighting the importance of&#13;
public health advocacy, education on safe handling, and governmental regulation of toxic substances. Both survey&#13;
and interview data highlighted challenges stemming from inconsistent availability of resources and underscored the&#13;
need for tailored education to manage poisoned patients with locally available resources.&#13;
Conclusions Our findings indicate the need to focus on the most prevalent local toxicological presentations and&#13;
practical management challenges in local contexts, including resource limitations and delayed presentations.&#13;
Moreover, it emphasizes the importance of public health initiatives such as regulation of the sale and promotion of</text>
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              <elementText elementTextId="132634">
                <text>Anna Nowacki1,2,5,8*, Sofia Kebede3,5, Margaret Thompson1,4, Alexandra McKnight5&#13;
&#13;
, Aklilu Azazh3,5 and Lisa M&#13;
&#13;
Puchalski Ritchie1,2,6,7</text>
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              <elementText elementTextId="132635">
                <text>https://doi.org/10.1186/s12245-024-00696-0</text>
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          <element elementId="40">
            <name>Date</name>
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              <elementText elementTextId="132636">
                <text>2024</text>
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          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132637">
                <text>Peri Irawan</text>
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            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132639">
                <text>english</text>
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        <name>Toxicology, Emergency medicine training, Curriculum, Sub-specialty</name>
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                  <text>Volume 17 Issue 1 2024</text>
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              <elementTextContainer>
                <elementText elementTextId="130913">
                  <text>peri irawan</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132621">
                <text>Unexpected Grave’s-induced acute myocardial&#13;
infarction in a young female, a literature&#13;
review based on a case report</text>
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          <element elementId="49">
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            <description>The topic of the resource</description>
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              <elementText elementTextId="132622">
                <text>Myocardial ischemia, Hyperthyroidism, Acute coronary syndrome, Interventional cardiology, Case report</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132623">
                <text>Abstract&#13;
Introduction Myocardial ischemia can occur due to several causes, which result in an imbalance between the supply&#13;
and demand of oxygen to cardiac muscles. One potential reason for this condition is the overwork of the heart due to&#13;
hyperstimulated thyroid function.&#13;
Case presentation The patient was a 36-year-old woman who presented with left-sided chest pain, dyspnea,&#13;
palpitation, and tremor. The initial evaluation showed evidence of myocardial ischemia (positive high-sensitivity&#13;
troponin) caused by a hyperactive thyroid gland. The treatment for myocardial infarction, along with anti-thyroid&#13;
medications, improved the patient’s condition and subsided the symptoms. The coronary angiography revealed no&#13;
pathologic finding, and the hypokinetic left ventricle, observed in the first echocardiogram, was resolved. The patient&#13;
was discharged with an excellent clinical condition, and after the 4-month taking of a calcium channel blocker and&#13;
tapering carbimazole, the thyroid function became normal, and her symptoms resolved completely.&#13;
Conclusion Patients without evident risk factors for ischemic heart disease, such as non-diabetic, nonsmoker, and&#13;
young individuals who presented with acute coronary syndrome, should be evaluated for a potential background&#13;
reason for the imbalance between the oxygen demand and supply of the myocardium. The presence of palpitation,&#13;
weight loss, tremors, insomnia, and anxiousness, along with ischemic signs, should make the physician think about&#13;
the probability of the hyperthyroid-induced cardiovascular disorder.&#13;
Clinical key point The initial presentation of hyperthyroidism might be accompanied by severe cardiac symptoms.&#13;
When the demographic features are not aligned with usual ischemic heart disease, other probable symptoms and&#13;
signs should be investigated, and thyroid function should be checked. The control of thyroid hyperactivity would&#13;
result in the resolution of both cardiac and non-cardiac symptoms.&#13;
Keywords Myocardial ischemia, Hyperthyroidism, Acute coronary syndrome, Interventional cardiology, Case report</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132624">
                <text>Fatemeh Naderi1*, Narges Naderi2&#13;
&#13;
, Seyedeh Maryam Mousavinezhad3&#13;
&#13;
and Amin Zaki Zadeh3</text>
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            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="132625">
                <text>https://doi.org/10.1186/s12245-024-00695-1</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="132626">
                <text>2024</text>
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          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132627">
                <text>Peri Irawan</text>
              </elementText>
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            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132629">
                <text>english</text>
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              <description>A name given to the resource</description>
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                <elementText elementTextId="130912">
                  <text>Volume 17 Issue 1 2024</text>
                </elementText>
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            <element elementId="37">
              <name>Contributor</name>
              <description>An entity responsible for making contributions to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="130913">
                  <text>peri irawan</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132611">
                <text>Provider perception of presentations&#13;
with nonspecific back pain in the emergency&#13;
department and primary care practices:&#13;
a semi-structured interview study</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132612">
                <text>Health resources, Triage, Health personnel, Emergency Medicine, Interview, Low back Pain, Physician-&#13;
patient relations</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132613">
                <text>Abstract&#13;
Background Increasing numbers of patients treated in the emergency departments pose challenges to delivering&#13;
timely and high-quality care. Particularly, the presentation of patients with low-urgency complaints consumes&#13;
resources needed for patients with higher urgency. In this context, patients with non-specific back pain (NSBP) often&#13;
present to emergency departments instead of primary care providers. While patient perspectives are well understood,&#13;
this study aims to add a provider perspective on the diagnostic and therapeutic approach for NSBP in emergency and&#13;
primary care settings.&#13;
Methods In a qualitative content analysis, we interviewed seven Emergency Physicians (EP) and nine General&#13;
Practitioners (GP) using a semi-structured interview to assess the diagnostic and therapeutic approach to patients&#13;
with NSBP in emergency departments and primary care practices. A hypothetical case of NSBP was presented to&#13;
the interviewees, followed by questions on their diagnostic and therapeutic approaches. Recruitment was stopped&#13;
after reaching saturation of the qualitative content analysis. Reporting this work follows the consolidated criteria for&#13;
reporting qualitative research (COREQ) checklist.&#13;
Results EPs applied two different strategies for the workup of NSBP. A subset pursued a guideline-compliant&#13;
diagnostic approach, ruling out critical conditions and managing pain without extensive diagnostics. Another group&#13;
of EPs applied a more extensive approach, including extensive diagnostic resources and specialist consultations. GPs&#13;
emphasized physical examinations and stepwise treatment, including scheduled follow-ups and a better knowledge&#13;
of the patient history to guide diagnostics and therapy. Both groups attribute ED visits for NSBP to patient related and&#13;
healthcare system related factors: lack of understanding of healthcare structures, convenience, demand for immediate&#13;
diagnostics, and fear of serious conditions. Furthermore, both groups reported an ill-suited healthcare infrastructure&#13;
with insufficiently available primary care services as a contributing factor.</text>
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            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132614">
                <text>Leo Benning1*, Nora Köhne2&#13;
&#13;
, Hans-Jörg Busch1&#13;
&#13;
and Felix Patricius Hans1</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="132615">
                <text>https://doi.org/10.1186/s12245-024-00694-2</text>
              </elementText>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132616">
                <text>2024</text>
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          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132617">
                <text>Peri Irawan</text>
              </elementText>
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          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132619">
                <text>english</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Volume 17 Issue 1 2024</text>
                </elementText>
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            <element elementId="37">
              <name>Contributor</name>
              <description>An entity responsible for making contributions to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="130913">
                  <text>peri irawan</text>
                </elementText>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132601">
                <text>Cervical epidural hematoma: a case series highlighting uncommon causes</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132602">
                <text>Spinal epidural hematoma, Neck strain, Acupuncture, Hemiparalysis, Decompression</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132603">
                <text>Abstract&#13;
Background Cervical epidural hematoma (CEH) is a rare but potentially devastating condition, characterized by&#13;
the accumulation of blood within the epidural space of the cervical spine, leading to spinal cord compression&#13;
(Perron AD, Huff JS. Spinal cord disorders. In: Marx JA, et al. editors. Rosen’s emergency medicine: concepts and&#13;
clinical practice. 8th ed. Philadelphia: Saunders; 2013. pp. 1419–27.); (Raasck K, Habis AA, Aoude A, Simoes L, Barros F,&#13;
Reindl R. Spontaneous spinal epidural hematoma management: a case series and literature review. Spinal Cord Ser&#13;
Cases. 2017;3:16043. https://doi.org/10.1038/scsandc.2016.43.); (Ryo Yamamoto M, Ito H, Shimuzu K, Wakabayashi&#13;
H, Oyama. Two cases of cervical epidural hematoma presenting with left-sided hemiplegia and requiring surgical&#13;
drainage. Cureus. 2022;14(4):e23915. https://doi.org/10.7759/cureus.23915.). While trauma and iatrogenic causes&#13;
are well-documented, cases attributed to neck strain and acupuncture are uncommon. (Raasck K, Habis AA, Aoude&#13;
A, Simoes L, Barros F, Reindl R. Spontaneous spinal epidural hematoma management: a case series and literature&#13;
review. Spinal Cord Ser Cases. 2017;3:16043. https://doi.org/10.1038/scsandc.2016.43.); (Shiraishi S, Goto I, Kuroiwa Y,&#13;
Nishio S, Kinoshita K. Spinal cord injury as a complication of an acupuncture. Neurology. 1979;29(8):1188–90. https://&#13;
doi.org/10.1212/wnl.29.8.1188.) Here, we present two cases of CEH secondary to these unusual aetiologies. Both&#13;
cases highlight the importance of considering uncommon causes of CEH to ensure early recognition and prompt&#13;
treatment.&#13;
Case presentations Case 1 is an 81-year-old lady who presented with left hemiparesis and paraesthesia following a&#13;
fall with neck strain. Magnetic resonance imaging (MRI) of cervical spine revealed left C3-C7 epidural haematoma with&#13;
severe cord compression. In Case 2, a 35-year-old gentleman experienced sudden onset numbness and weakness in&#13;
all limbs just 10 minutes after receiving acupuncture. MRI showed an epidural hematoma at the C2-C4 levels. Both&#13;
patients underwent immediate surgical decompression and had significant recovery.&#13;
Conclusion Although CEH is a rare occurrence, it can potentially be a neurosurgical emergency. Physicians&#13;
must remain cognizant of the diverse aetiologies associated with CEH and the necessity for early recognition and&#13;
immediate treatment.&#13;
Keywords Spinal epidural hematoma, Neck strain, Acupuncture, Hemiparalysis, Decompression</text>
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              <elementText elementTextId="132604">
                <text>Wey Ting Lee1*, Joan Rui Shan Fun1&#13;
&#13;
and Yi Wen Mathew Yeo1</text>
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            <elementTextContainer>
              <elementText elementTextId="132605">
                <text>https://doi.org/10.1186/s12245-024-00693-3</text>
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            <elementTextContainer>
              <elementText elementTextId="132607">
                <text>Peri Irawan</text>
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                  <text>Volume 17 Issue 1 2024</text>
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                <text>Vaping‐associated illness: a reassessment</text>
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                <text>Abstract&#13;
Background In 2019, there was widespread presentation of respiratory distress as well as other organ system&#13;
involvement in patients with a history of vaping. There continue to be reports of vaping-associated illness (VAI). This&#13;
has come to be known as e-cigarette and vaping product associated lung injury (EVALI). The mechanism of injury&#13;
remains unclear.&#13;
Objectives This study reexamines the clinical characteristics of patients affected by vaping and suggests that lung&#13;
injury may not be the primary organ dysfunction but be part of a larger systemic illness.&#13;
&#13;
Methods This is a retrospective chart review of all patients presenting to one hospital identified as having vaping-&#13;
associated illness&#13;
&#13;
Results Fourteen patients were identified ranging in age from 15 to 33 years. Patients had a broad range of clinical&#13;
&#13;
severity. Respiratory symptoms occurred in 64%, gastrointestinal symptoms in 57%, fever in 78%, neurological symp-&#13;
toms in 15% and other constitutional symptoms in 50%. 35% presented with no respiratory symptoms.&#13;
&#13;
Conclusion While the lungs are certainly involved in vaping-associated illness, recognizing the extent of involve-&#13;
ment of other organ systems may provide insight into the pathophysiology of the disease. Providers should be aware&#13;
&#13;
that vaping-associated illness presents with a multitude of symptoms outside of lung injury, such as abdominal pain,&#13;
headache or even fever.&#13;
Keywords Vaping, E-cigarette, Abdominal pain, Lung injury</text>
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                <text>Jonathan S. Schiffman1*</text>
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            <elementTextContainer>
              <elementText elementTextId="132595">
                <text>https://doi.org/10.1186/s12245-024-00692-4</text>
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            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132597">
                <text>Peri Irawan</text>
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            <elementTextContainer>
              <elementText elementTextId="132599">
                <text>english</text>
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                  <text>Volume 17 Issue 1 2024</text>
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                <text>Cytokine release syndrome&#13;
following COVID‐19 infection during treatment&#13;
with nivolumab for cancer of esophagogastric&#13;
junction carcinoma: a case report and review</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="49">
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                <text>Immune-related adverse event, Cytokine release syndrome, Immune checkpoint inhibitor</text>
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              <elementText elementTextId="132583">
                <text>Abstract&#13;
Background Cytokine release syndrome (CRS) is an acute systemic inflammatory syndrome characterized by fever&#13;
and multiple organ failure, which is triggered by immunotherapy or certain infections. Immune checkpoint inhibitors&#13;
rarely cause immune-related adverse event- cytokine release syndrome (irAE-CRS). This article presents a case report&#13;
of irAE-CRS triggered by coronavirus disease 2019 (COVID-19).&#13;
&#13;
Case presentation A 60-year-old man with type 2 diabetes received nivolumab treatment for esophagogastric junc-&#13;
tion carcinoma and experienced two immune-related adverse events: hypothyroidism and skin disorder. Eleven days&#13;
&#13;
before his visit to our hospital, he had a fever and was diagnosed with COVID-19. Five days before his visit, he devel-&#13;
oped a fever again, along with general malaise, water soluble diarrhea, and myalgia of the extremities. On admission,&#13;
&#13;
the patient was in a state of multiple organ failure, and although the source of infection was unknown, a tentative&#13;
&#13;
diagnosis of septic shock was made. The patient’s condition was unstable despite systemic management with antimi-&#13;
crobial agents, high-dose vasopressors, and intravenous fluids. We suspected CRS due to irAE (irAE-CRS) based on his&#13;
&#13;
history of nivolumab use. Steroid pulse therapy (methylprednisolone 1 g/day) was started, and the patient temporarily&#13;
recovered. However, his respiratory condition worsened; consequently, he was placed on a ventilator and tocilizumab&#13;
&#13;
was added to the treatment. His muscle strength recovered to the point where he could live at home, and was subse-&#13;
quently discharged.&#13;
&#13;
Conclusion In patients previously treated with immune checkpoint inhibitors, irAE-CRS should be considered&#13;
&#13;
as a differential diagnosis when multiple organ damage is observed in addition to inflammatory findings. It is recom-&#13;
mended to start treatment with steroids; if the disease is refractory, other immunosuppressive therapies such as tocili-&#13;
zumab should be introduced as early as possible.&#13;
&#13;
Keywords Immune-related adverse event, Cytokine release syndrome, Immune checkpoint inhibitor</text>
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            <elementTextContainer>
              <elementText elementTextId="132584">
                <text>Takahisa Niimoto1,2*, Takafumi Todaka1&#13;
&#13;
, Hirofumi Kimura1&#13;
&#13;
, Shotaro Suzuki2&#13;
&#13;
, Shumpei Yoshino2&#13;
,&#13;
&#13;
Kosuke Hoashi3 and Hirotaka Yamaguchi1</text>
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            <elementTextContainer>
              <elementText elementTextId="132585">
                <text>https://doi.org/10.1186/s12245-024-00691-5</text>
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                <text>Peri Irawan</text>
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                  <text>Volume 17 Issue 1 2024</text>
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            <description>A name given to the resource</description>
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                <text>Management of gunshot injury to the&#13;
abdominal aorta and inferior vena cava: a case&#13;
report of a combat patient wounded in the&#13;
Russo-Ukrainian war</text>
              </elementText>
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          <element elementId="49">
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              <elementText elementTextId="132572">
                <text>Russo-Ukrainian war is associated with severe traumas, including injuries to the major vessels.</text>
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            <description>An account of the resource</description>
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              <elementText elementTextId="132573">
                <text>Abstract&#13;
Background Russo-Ukrainian war is associated with severe traumas, including injuries to the major vessels.&#13;
Penetrating aortic injury remains one of the most difficult injuries; the mortality rate is 90–100% in case of gunshot&#13;
wounds, associated with frequent lethal outcomes due to uncontrolled bleeding. Of the three main abdominal&#13;
veins, the inferior vena cava (IVC) is the most frequently damaged, which is required quick and appropriate surgical&#13;
decisions to be made. Little is known about the management of gunshot injuries to such major vessels as the aorta&#13;
and IVC. It is also worth mentioning about the importance to share our practical experience from the ongoing war&#13;
for better understanding and future considerations by war surgeons of the vascular trauma management. The aim&#13;
of the study was to demonstrate the specific features of the diagnosis and management of a gunshot shrapnel blind&#13;
penetrating wound to the abdomen with injury to the aortic bifurcation level and the infrarenal section of the inferior&#13;
vena cava.&#13;
Case presentation A 44-year-old male soldier of the Armed Forces of Ukraine received a gunshot injury to the&#13;
abdomen from a mortars’ explosive shelling. The patient was evacuated to the Forward Surgical Team (Role 1) and&#13;
received primary surgical treatment within one hour after the injury according to the “golden hour” principle. Then,&#13;
&#13;
evacuated was performed to the Role 3 hospital in Kharkiv. At the Role 3 hospital, the patient underwent second-&#13;
look surgery as well as damage control surgery. At revision, no active bleeding was observed, and the surgical pads&#13;
&#13;
(packed previously by the Forward Surgical Team) were removed. Further revision showed a metal projectile within&#13;
the aortic wall at the level of aortic bifurcation and wall defects were also detected for inferior vena cava. This metal&#13;
projectile was removed by using the multifunctional surgical magnetic tool followed by suturing of the aortic wall&#13;
defect as well as defects of the inferior vena cava.&#13;
Conclusions Application of Damage Control Surgery is a useful approach in the management of severe vascular&#13;
injury as well as useful to stop abdominal contamination by intestinal contents. The application of a surgical magnetic</text>
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                <text>Igor Lurin1,2, Eduard Khoroshun3,4, Vitalii Makarov3,4, Volodymyr Negoduiko3,4, Serhii Shypilov3,4, Yurii Bunin3&#13;
,&#13;
&#13;
Maksym Gorobeiko1,5,6 and Andrii Dinets1,5,7*</text>
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              <elementText elementTextId="132575">
                <text>https://doi.org/10.1186/s12245-024-00690-6</text>
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                <text>Right iliac deep vein thrombosis&#13;
and pulmonary embolism associated&#13;
with recreational nitrous oxide: a case report</text>
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                <text>Thrombosis, Pulmonary embolism, Nitrous oxide abuse, Vitamin B12, Hyperhomocysteinaemia</text>
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            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132563">
                <text>Abstract&#13;
Background The recreational use of nitrous oxide is becoming increasingly common among teenagers and young&#13;
adults. Since 2018, the use of nitrous oxide has increased exponentially and has become a public health problem.&#13;
Case presentation A 23-year-old patient was referred to accident and emergency (A&amp;E) by his general practitioner&#13;
for deterioration in general condition, vomiting, diarrhea and febrile headache at 39 °C.&#13;
He reported that he had been partying for a month and consuming alcohol, cannabis and nitrous oxide. Three&#13;
&#13;
days before the consultation, he reported increased abdominal pain in the right iliac fossa. His homocysteine con-&#13;
centration was 51.9 μmol/L, and his plasma methyl malonate concentration increased to 4.45 μmol/L. A thoracic&#13;
&#13;
and abdominal CT scan revealed right iliac venous thrombosis associated with bilateral pulmonary embolism.&#13;
Conclusion Nitrous oxide inhibits the activity of methionine synthetase. We therefore observed an increase&#13;
&#13;
in plasma homocysteine and 5-methyl-THF. The increase in homocysteine could be responsible for the pro-throm-&#13;
botic activity resulting from nitrous oxide intoxication. At present, no threshold or duration of exposure has been&#13;
&#13;
identified as being particularly likely to cause complications. It is likely that other factors coexist, such as coagulation&#13;
&#13;
disorders and polymorphisms of the MHTFR gene, which can lead to hyperhomocysteinaemia, cannabis consump-&#13;
tion, inflammatory conditions and others. Treatment is based on vitamin B12 supplementation and curative antico-&#13;
agulation. Some authors also recommend folate supplementation.&#13;
&#13;
Consumption of nitrous oxide could be associated with arterial and venous thromboembolic disease.&#13;
Keywords Thrombosis, Pulmonary embolism, Nitrous oxide abuse, Vitamin B12, Hyperhomocysteinaemia</text>
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            <name>Creator</name>
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            <elementTextContainer>
              <elementText elementTextId="132564">
                <text>Thomas Bizouard1*, Catherine Caplette1&#13;
&#13;
, Damien Duval1&#13;
&#13;
, Dominique Savary1,2 and Delphine Douillet1,2,3</text>
              </elementText>
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            <name>Source</name>
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            <elementTextContainer>
              <elementText elementTextId="132565">
                <text>https://doi.org/10.1186/s12245-024-00689-z</text>
              </elementText>
            </elementTextContainer>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132566">
                <text>2024</text>
              </elementText>
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          <element elementId="37">
            <name>Contributor</name>
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            <elementTextContainer>
              <elementText elementTextId="132567">
                <text>Peri Irawan</text>
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            <elementTextContainer>
              <elementText elementTextId="132569">
                <text>english</text>
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        </elementContainer>
      </elementSet>
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    <tagContainer>
      <tag tagId="15267">
        <name>Thrombosis, Pulmonary embolism, Nitrous oxide abuse, Vitamin B12, Hyperhomocysteinaemia</name>
      </tag>
    </tagContainer>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="130912">
                  <text>Volume 17 Issue 1 2024</text>
                </elementText>
              </elementTextContainer>
            </element>
            <element elementId="37">
              <name>Contributor</name>
              <description>An entity responsible for making contributions to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="130913">
                  <text>peri irawan</text>
                </elementText>
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        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132551">
                <text>An unsuspected extracranial internal carotid&#13;
pseudoaneurysm following dog bites: a case&#13;
report and review of literature</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132552">
                <text>Animals, Bites, Carotid artery, False aneurysm, Vascular Surgical Procedure</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132553">
                <text>Abstract&#13;
Background Extracranial internal carotid artery (ICA) pseudoaneurysm is a rare condition that can be caused&#13;
either by penetrating or blunt trauma, including dog bites, which is an uncommon occurrence. Together with the&#13;
possibility of no symptoms or nonspecific ones such as cervical pain, hematoma, swelling, or mass, considering ICA&#13;
pseudoaneurysm following a dog attack is of paramount importance to avoid life-threatening complications.&#13;
Case presentation We present a rare case of a 17-year-old male with a history of dog bites three months prior, who&#13;
presented to the emergency department with left-sided neck pain, dizziness, and several episodes of blurred vision&#13;
and diplopia. On physical examination, a palpable mass measuring approximately 20×30 millimeters was identified&#13;
in the left neck region and multiple superficial lacerations were observed in this area. Laboratory tests yielded&#13;
normal results. Doppler ultrasound revealed a pseudoaneurysm in the left internal carotid artery. Because the great&#13;
saphenous veins were insufficient, the patient was successfully treated with synthetic graft patch arterioplasty, and no&#13;
complications were seen in his one-year follow-up with computed tomography (CT) angiography.&#13;
Conclusions This report emphasizes the significance of thorough initial evaluation and imaging in cases of dog&#13;
attacks, even without apparent significant trauma, to rule out hidden arterial injuries.&#13;
Keywords Animals, Bites, Carotid artery, False aneurysm, Vascular Surgical Procedure</text>
              </elementText>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132554">
                <text>Ahmad Hosseinzadeh1&#13;
&#13;
, Reza Shahriarirad1,2, Farzad Dalfardi1&#13;
&#13;
, Human Arianpour1&#13;
&#13;
and Fatemeh Zarimeidani1,3*</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="132555">
                <text>https://doi.org/10.1186/s12245-024-00688-0</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132556">
                <text>2024</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132557">
                <text>Peri Irawan</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="42">
            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132558">
                <text>pdf</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132559">
                <text>english</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="51">
            <name>Type</name>
            <description>The nature or genre of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132560">
                <text>text</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
    <tagContainer>
      <tag tagId="15266">
        <name>Animals, Bites, Carotid artery, False aneurysm, Vascular Surgical Procedure</name>
      </tag>
    </tagContainer>
  </item>
  <item itemId="12406" public="1" featured="1">
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          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="130912">
                  <text>Volume 17 Issue 1 2024</text>
                </elementText>
              </elementTextContainer>
            </element>
            <element elementId="37">
              <name>Contributor</name>
              <description>An entity responsible for making contributions to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="130913">
                  <text>peri irawan</text>
                </elementText>
              </elementTextContainer>
            </element>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132541">
                <text>Neuraxial anesthesia for non-neurological&#13;
emergency surgery in a patient with acute&#13;
ischemic stroke: a case report</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132542">
                <text>Emergency surgery, Neuraxial anesthesia, Stroke</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132543">
                <text>Abstract&#13;
Background The recent guidelines recommend delaying elective non-neurological surgery after an index stroke,&#13;
but there is a lack of consensus regarding emergency surgery in patients with a recent stroke. Impaired cerebral&#13;
autoregulation and altered baroreceptor function elevate the risk of recurrent stroke in this group. Moreover, the&#13;
impact of anesthesia type (general vs. regional) for non-cardiovascular, non-neurological surgery in patients with an&#13;
index stroke remains inconclusive.&#13;
Case presentation A 67-year-old male with an acute mild ischemic stroke underwent emergency surgery for an&#13;
obstructed right-sided direct inguinal hernia under combined spinal-epidural anesthesia. Pre-operative assessment&#13;
showed stable hemodynamics, and perioperative measures were taken to ensure stable blood pressure. Neuraxial&#13;
anesthesia was employed successfully, and the patient remained hemodynamically stable throughout the surgery&#13;
and postoperative period. No neurological deficits were observed post-surgery, and follow-up up to 3 months&#13;
revealed no cognitive impairment or neurological decline.&#13;
&#13;
Conclusions Neuraxial anesthesia can be considered for patients with acute mild strokes requiring urgent non-&#13;
neurological surgery, provided they are hemodynamically stable and without coagulopathy. However, the choice of&#13;
&#13;
anesthesia should be individualized based on factors such as neurological status, stroke severity, coagulation, and&#13;
existing disabilities. This case highlights the importance of a personalized approach to anesthesia in emergency&#13;
surgery for stroke patients.&#13;
Keywords Emergency surgery, Neuraxial anesthesia, Stroke</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132544">
                <text>Asish Subedi1* and Ashok Gautam1</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="132545">
                <text>https://doi.org/10.1186/s12245-024-00687-1</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132546">
                <text>2024</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132547">
                <text>Peri Irawan</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="42">
            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
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              <elementText elementTextId="132548">
                <text>pdf</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132549">
                <text>english</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="51">
            <name>Type</name>
            <description>The nature or genre of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="132550">
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    <tagContainer>
      <tag tagId="15265">
        <name>Emergency surgery, Neuraxial anesthesia, Stroke</name>
      </tag>
    </tagContainer>
  </item>
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