Effect of combined lateral and supine positioning on oxygen saturation in ICU patients during the mechanical ventilator weaning process: A randomized controlled trial
Dublin Core
Title
Effect of combined lateral and supine positioning on oxygen saturation in ICU patients during the mechanical ventilator weaning process: A randomized controlled trial
Subject
critical patients; lateral position; mechanical ventilation; oxygen
saturation
saturation
Description
Background: Prolonged mechanical ventilation in ICU patients increases
mortality risk and length of stay. Ineffective weaning can exacerbate the
patient’s condition and further elevate mortality risk due to hypoxemiainduced
cellular damage, contributing to ICU overcrowding.
Purpose: This study investigates the effect of lateral positioning on oxygen
saturation in ICU patients undergoing mechanical ventilator weaning.
Methods: A randomized controlled trial (RCT) with block randomization was
conducted, enrolling 60 participants assigned to either the intervention group
(n = 30) or the control group (n = 30). The intervention group received 5%
FiO2 and was repositioned every two hours (right lateral, supine, left lateral),
whereas the control group remained supine with 5% FiO2. Oxygen saturation
(SaO2) was measured using pulse oximetry before and after the intervention.
As the data were not normally distributed, the Mann-Whitney U test was
used to compare SaO2 changes between groups, with statistical significance
set at p < 0.05.
Results: Baseline characteristics, including age, gender, and ventilator
duration, were comparable between groups (p > 0.05). The median increase
in SaO2 was 6% (IQR: 1–8%) in the intervention group and 1% (IQR: 0–3%)
in the control group, with a significant between-group difference of 5% (p <
0.001). A large effect size (η² = 0.68) indicated a substantial impact of lateral
positioning on SaO2.
Conclusions: Lateral positioning significantly improves oxygen saturation
in ICU patients undergoing ventilator weaning, potentially reducing
complications associated with prolonged mechanical ventilation.
mortality risk and length of stay. Ineffective weaning can exacerbate the
patient’s condition and further elevate mortality risk due to hypoxemiainduced
cellular damage, contributing to ICU overcrowding.
Purpose: This study investigates the effect of lateral positioning on oxygen
saturation in ICU patients undergoing mechanical ventilator weaning.
Methods: A randomized controlled trial (RCT) with block randomization was
conducted, enrolling 60 participants assigned to either the intervention group
(n = 30) or the control group (n = 30). The intervention group received 5%
FiO2 and was repositioned every two hours (right lateral, supine, left lateral),
whereas the control group remained supine with 5% FiO2. Oxygen saturation
(SaO2) was measured using pulse oximetry before and after the intervention.
As the data were not normally distributed, the Mann-Whitney U test was
used to compare SaO2 changes between groups, with statistical significance
set at p < 0.05.
Results: Baseline characteristics, including age, gender, and ventilator
duration, were comparable between groups (p > 0.05). The median increase
in SaO2 was 6% (IQR: 1–8%) in the intervention group and 1% (IQR: 0–3%)
in the control group, with a significant between-group difference of 5% (p <
0.001). A large effect size (η² = 0.68) indicated a substantial impact of lateral
positioning on SaO2.
Conclusions: Lateral positioning significantly improves oxygen saturation
in ICU patients undergoing ventilator weaning, potentially reducing
complications associated with prolonged mechanical ventilation.
Creator
Iwan Purnawan1* , Putut Anggara Susetya2, Arif Imam Hidayat1 ,
Galih Noor Alivian1 , Sidik Awaludin1 , Ikit Netra Wirakhmi3 , Sawinee
Chanshintop4
Galih Noor Alivian1 , Sidik Awaludin1 , Ikit Netra Wirakhmi3 , Sawinee
Chanshintop4
Source
http://jkp.fkep.unpad.ac.id/index.
php/jkp
php/jkp
Date
April 25, 2025
Contributor
peri irawan
Format
pdf
Language
english
Type
text
Files
Collection
Citation
Iwan Purnawan1* , Putut Anggara Susetya2, Arif Imam Hidayat1 ,
Galih Noor Alivian1 , Sidik Awaludin1 , Ikit Netra Wirakhmi3 , Sawinee
Chanshintop4, “Effect of combined lateral and supine positioning on oxygen saturation in ICU patients during the mechanical ventilator weaning process: A randomized controlled trial,” Repository Horizon University Indonesia, accessed February 12, 2026, https://repository.horizon.ac.id/items/show/10768.