Music Therapy and Psychoneuroimmunological Markers in Children With Chronic Disease: A Systematic Review
Dublin Core
Title
Music Therapy and Psychoneuroimmunological Markers in Children With Chronic Disease: A Systematic Review
Subject
child, chronic disease; music therapy, psychoneuroimmunology
Description
Stress conditions in children with chronic disease affect psychoneuroimmunological markers. One of
the mind-body modalities commonly used in pediatric chronic disease is music therapy. This systematic aim was
evaluating the effect of music therapy on psychoneuroimmunological markers among children with chronic
disease. Articles published between March 31, 2014, and April 1, 2023, were retrieved from five databases: Scopus,
PubMed, Web of Science, EBSCOhost, and ProQuest. Rayyan, an AI-powered tool for systematic literature
reviews, facilitated paper selection. Studies were screened based on pre-defined inclusion and exclusion criteria.
The PRISMA checklist guided selection, and the JBI Critical Appraisal for quality assessment. Data analysis
employed a descriptive approach. A total of 15 articles published between 2014 and 2023 were included in this
review. 10 (66,7%) of 15 studies assessed the effectiveness of music therapy on psychological and physiological
responses. Meanwhile, five (33,3%) studies assessed the effectiveness of music therapy on neuroimmunological
markers. Among the five studies, one did not exhibit a statistically significant impact. In contrast, the remaining
four studies displayed a significant impact of music therapy on neuroimmunological markers. The most studies
assessed the impact of music therapy on psychological and physiological responses, but only a small proportion
assessed the effectiveness of music therapy on neuroimmunological markers. Music therapy can be considered a safe and generally well-accepted intervention in pediatric health care to manage sychoneuroimmunological markers.
the mind-body modalities commonly used in pediatric chronic disease is music therapy. This systematic aim was
evaluating the effect of music therapy on psychoneuroimmunological markers among children with chronic
disease. Articles published between March 31, 2014, and April 1, 2023, were retrieved from five databases: Scopus,
PubMed, Web of Science, EBSCOhost, and ProQuest. Rayyan, an AI-powered tool for systematic literature
reviews, facilitated paper selection. Studies were screened based on pre-defined inclusion and exclusion criteria.
The PRISMA checklist guided selection, and the JBI Critical Appraisal for quality assessment. Data analysis
employed a descriptive approach. A total of 15 articles published between 2014 and 2023 were included in this
review. 10 (66,7%) of 15 studies assessed the effectiveness of music therapy on psychological and physiological
responses. Meanwhile, five (33,3%) studies assessed the effectiveness of music therapy on neuroimmunological
markers. Among the five studies, one did not exhibit a statistically significant impact. In contrast, the remaining
four studies displayed a significant impact of music therapy on neuroimmunological markers. The most studies
assessed the impact of music therapy on psychological and physiological responses, but only a small proportion
assessed the effectiveness of music therapy on neuroimmunological markers. Music therapy can be considered a safe and generally well-accepted intervention in pediatric health care to manage sychoneuroimmunological markers.
Creator
Idyatul Hasanah, Chui Ping Lei, Zikrul Haikal, Apriani Susmita Sari, Domingos Soares, Kurniati Prihatin
Source
https://doi.org/10.23917/bik.v18i1.7517
Publisher
Universitas Muhammadiyah Surakarta
Date
2025
Contributor
Sri Wahyuni
Rights
p-ISSN: 1979-2697
e-ISSN: 2721-1797
e-ISSN: 2721-1797
Format
PDF
Language
English
Type
Text
Files
Collection
Citation
Idyatul Hasanah, Chui Ping Lei, Zikrul Haikal, Apriani Susmita Sari, Domingos Soares, Kurniati Prihatin, “Music Therapy and Psychoneuroimmunological Markers in Children With Chronic Disease: A Systematic Review,” Repository Horizon University Indonesia, accessed February 12, 2026, https://repository.horizon.ac.id/items/show/10790.