Self-efficacy, drug side effects, and nurse communication: Factors related
in chemotherapy adherence for breast cancer patients

Dublin Core

Title

Self-efficacy, drug side effects, and nurse communication: Factors related
in chemotherapy adherence for breast cancer patients

Subject

adverse reactions; breast cancer; chemotherapy; drug-related
side effect; patient compliance

Description

Background: Chemotherapy is a crucial therapy for breast cancer patients,
and its success heavily depends on patient compliance. However, despite
extensive in the impact of Non-compliance, there is still limited understanding
of the specific factors influencing chemotherapy adherence among breast
cancer patients, highlighting the need to re identify these contributing factors.
Purpose: This study aims to identify the determinant factors related to
chemotherapy adherence among breast cancer patients at the West
Sumatera Provincial Hospital.
Methods: This study is a quantitative research with a cross-sectional design.
An accidental sampling technique was used, with a total of 81 patients.
Bivariate analysis was conducted using the chi-square test (p < 0.05), and
multivariate analysis was performed using Multiple Logistic Regression.
Results: The results showed that 61.7% of patients had good compliance.
Factors associated with compliance included good self-efficacy, low
knowledge, feeling bothered by the side effects of chemotherapy drugs, and
effective nurse interpersonal communication. Multivariate analysis revealed
that self-efficacy and drug side effects had a significant relationship with
compliance (p < 0.05). Drug side effects were the most significant factor (OR
= 12.223, 95% CI: 1.371 to 109.015, p < 0.05).
Conclusion: The findings of this study highlight the importance of managing
drug side effects and enhancing self-efficacy through patient education
and improved nurse interpersonal communication. These measures are
expected to improve the quality of nursing care and patient outcomes.

Creator

Muhammad Ashraf1 , Hema Malini2* , Randy Refnandez3

, Intan Yullya

Kardila4

Source

http://jkp.fkep.unpad.ac.id/index.
php/jkp

Date

December 10, 2025

Contributor

peri irawan

Format

pdf

Language

english

Type

text

Files

Citation

Muhammad Ashraf1 , Hema Malini2* , Randy Refnandez3 , Intan Yullya Kardila4, “Self-efficacy, drug side effects, and nurse communication: Factors related
in chemotherapy adherence for breast cancer patients,” Repository Horizon University Indonesia, accessed February 12, 2026, https://repository.horizon.ac.id/items/show/10829.