Factors Related to Fatigue among Chronic Kidney Disease Patients on Hemodialysis

Dublin Core

Title

Factors Related to Fatigue among Chronic Kidney Disease Patients on Hemodialysis

Subject

Chronic kidney disease; contributing factors; fatigue; hemodialysis

Description

Background: Fatigue is a common and distressing symptom among patients with
chronic kidney disease (CKD) undergoing hemodialysis, significantly impacting
their daily functioning and quality of life. Despite its prevalence, the contributing
factors to fatigue remain unclear and underexplored in specific populations.
Purpose: This study aimed to identify factors associated with fatigue among CKD
patients undergoing hemodialysis.
Methods: A cross-sectional study was conducted in two hemodialysis centers. A
total of 164 patients were recruited using convenience sampling, with sample size
determined through power analysis. Data were collected using the FACIT-Fatigue
Scale, a health literacy questionnaire, and an observation sheet for hemoglobin
(Hb), blood pressure, and interdialytic weight gain (IDWG). Patient characteristics
were also recorded. T-tests and ANOVA were used to examine differences in fatigue
levels across groups, while Spearman correlation and multiple linear regression
were employed to analyze associations between fatigue and clinical variables.
Results: The mean fatigue score was 28.23(SD=7.46). Fatigue was significantly
associated with age, education level, employment status, comorbidities, duration of
hemodialysis, systolic blood pressure, HB, IDWG, and health literacy (p<0.05).
Multiple linear regression identified employment status and hemoglobin levels as
the strongest predictors of fatigue.
Conclusion: Fatigue is a prevalent issue among CKD patients undergoing
hemodialysis and is influenced by a range of demographic, clinical, and behavioral
factors. Employment status and hemoglobin levels were the most significant
contributors. Interventions promoting physical activity, a healthy diet, and fluid
adherence, alongside routine monitoring of hemoglobin levels, may help reduce
fatigue and improve quality of life in this population.

Creator

Fitri Mailani1

, Arif Rohman Mansur1

, Aisyah Rifdatunnisa1

, Chong Mei Chan2

Source

https://doi.org/10.14710/nmjn.v15i1.59980

Date

29 April 2025

Contributor

peri irawan

Format

pdf

Language

english

Type

text

Files

Collection

Citation

Fitri Mailani1 , Arif Rohman Mansur1 , Aisyah Rifdatunnisa1 , Chong Mei Chan2, “Factors Related to Fatigue among Chronic Kidney Disease Patients on Hemodialysis,” Repository Horizon University Indonesia, accessed February 21, 2026, https://repository.horizon.ac.id/items/show/11311.