Time to achieve full enteral feeding in very low birth weight infants and Associated Factors in the Neonatology Unit
Dublin Core
Title
Time to achieve full enteral feeding in very low birth weight infants and Associated Factors in the Neonatology Unit
Subject
full enteral feeding,
very low birth
weight infants,
prematurity
very low birth
weight infants,
prematurity
Description
Introduction: Enteral intolerance in premature infants is associated with
several morbidities, especially in very low birth weight (VLBW). There are
only few dietary practices to provide better outcomes in newborns with
VLBW. This study aimed to assess the factors associated with the time to
achieve full enteral feeding (FEF) in infants with VLBW.
Methods: This was a retrospective study on infants with VLBW in the
Neonatology Unit of Sanglah Central General Hospital, Bali from November
2020 to January 2022. The infants started trophic feeding with breastmilk
and or formula milk. The age of FEF was determined when the target of
150 ml/kgBW/day was reached. The association of risk factors was
analyzed using the Mann Whitney test, the Kruskal-Wallis test, and linear
regression analysis.
Results: A total of 79 VLBW infants with the median gestational age of 30
weeks (25-38) were recruited. The median age of FEF was achieved in 9(7-
15) days. Late trophic feeding (more than 24 hours), severe asphyxia,
culture positive-sepsis, and using a mechanical ventilator were associated
with a longer timing of FEF. While in the multivariate analysis, small for
gestational age (SGA), late trophic feeding, severe asphyxia, absence of
prenatal dexamethasone, and culture-positive sepsis were independent
factors for longer FEF in this population.
Conclusion: In VLBW infants, the age of FEF in our population was reached
in 2 weeks. Small for gestational age, late trophic feeding, severe asphyxia,
prenatal dexamethasone coverage, and culture-positive sepsis were
associated with delay in FEF. Further studies of multi-centers and
analyzing the factors of delayed TF might be needed.
several morbidities, especially in very low birth weight (VLBW). There are
only few dietary practices to provide better outcomes in newborns with
VLBW. This study aimed to assess the factors associated with the time to
achieve full enteral feeding (FEF) in infants with VLBW.
Methods: This was a retrospective study on infants with VLBW in the
Neonatology Unit of Sanglah Central General Hospital, Bali from November
2020 to January 2022. The infants started trophic feeding with breastmilk
and or formula milk. The age of FEF was determined when the target of
150 ml/kgBW/day was reached. The association of risk factors was
analyzed using the Mann Whitney test, the Kruskal-Wallis test, and linear
regression analysis.
Results: A total of 79 VLBW infants with the median gestational age of 30
weeks (25-38) were recruited. The median age of FEF was achieved in 9(7-
15) days. Late trophic feeding (more than 24 hours), severe asphyxia,
culture positive-sepsis, and using a mechanical ventilator were associated
with a longer timing of FEF. While in the multivariate analysis, small for
gestational age (SGA), late trophic feeding, severe asphyxia, absence of
prenatal dexamethasone, and culture-positive sepsis were independent
factors for longer FEF in this population.
Conclusion: In VLBW infants, the age of FEF in our population was reached
in 2 weeks. Small for gestational age, late trophic feeding, severe asphyxia,
prenatal dexamethasone coverage, and culture-positive sepsis were
associated with delay in FEF. Further studies of multi-centers and
analyzing the factors of delayed TF might be needed.
Creator
Made Sukmawati1*
, I Made Kardana1, I Wayan Dharma Artana1, Putu Junara Putra1,
& Putu Mas Vina Paramitha Cempaka1, & Kartika Eda Clearesta1
, I Made Kardana1, I Wayan Dharma Artana1, Putu Junara Putra1,
& Putu Mas Vina Paramitha Cempaka1, & Kartika Eda Clearesta1
Source
https://doi.org/10.37363/bnr.2023.43270
Date
28 July 2023
Contributor
peri irawan
Format
pdf
Language
english
Type
text
Files
Collection
Citation
Made Sukmawati1*
, I Made Kardana1, I Wayan Dharma Artana1, Putu Junara Putra1,
& Putu Mas Vina Paramitha Cempaka1, & Kartika Eda Clearesta1, “Time to achieve full enteral feeding in very low birth weight infants and Associated Factors in the Neonatology Unit,” Repository Horizon University Indonesia, accessed April 25, 2026, https://repository.horizon.ac.id/items/show/11567.