Genotoxic Effects on Gas Station Attendants in South-southeastern
México due to Prolonged and Chronic Exposure to Gasoline
Dublin Core
Title
Genotoxic Effects on Gas Station Attendants in South-southeastern
México due to Prolonged and Chronic Exposure to Gasoline
México due to Prolonged and Chronic Exposure to Gasoline
Subject
Comet assay
DNA damage
Gas station attendants
DNA damage
Gas station attendants
Description
Gasoline, a complex mixture of volatile organic compounds is classified as possibly carcinogenic to humans. Gasoline station attendants, consistently exposed to its hazardous components, may
face genotoxic effects. This study aimed to assess the influence of varying work shift durations on DNA
damage in gasoline station attendants.
Methods: Ninety individuals from three locations in southern México were studied. Peripheral blood
mononuclear cells (PBMCs) were isolated, and DNA damage was assessed using the comet assay. Demographic, occupational, and lifestyle data were collected. Statistical analyses included t-tests, ANOVA,
and Pearson correlation.
Results: Significant differences in DNA damage parameters were observed between exposed and unexposed groups. The impact of tobacco, alcohol, and exercise on DNA damage was negligible. Extended
work shifts (12 and 24 hours) showed heightened DNA damage compared to 8-hour shifts and the
unexposed group. A novel finding revealed a modest but significant correlation between DNA damage
and job seniority.
Conclusion: The study highlights the intricate relationship between occupational exposure to gasoline
components, DNA damage, and work shift lengths. Extended shifts correlate with heightened genotoxic
effects, emphasizing the importance of personalized safety measures. The significant correlation between DNA damage and job seniority introduces occupational longevity as a determinant in the genetic
health of gasoline station attendants. This discovery has implications for implementing targeted interventions and preventive strategies to safeguard workers’ genetic integrity throughout their years of
service. The study calls for further exploration of unconsidered factors in understanding the multifactorial nature of DNA damage in this occupational setting.
face genotoxic effects. This study aimed to assess the influence of varying work shift durations on DNA
damage in gasoline station attendants.
Methods: Ninety individuals from three locations in southern México were studied. Peripheral blood
mononuclear cells (PBMCs) were isolated, and DNA damage was assessed using the comet assay. Demographic, occupational, and lifestyle data were collected. Statistical analyses included t-tests, ANOVA,
and Pearson correlation.
Results: Significant differences in DNA damage parameters were observed between exposed and unexposed groups. The impact of tobacco, alcohol, and exercise on DNA damage was negligible. Extended
work shifts (12 and 24 hours) showed heightened DNA damage compared to 8-hour shifts and the
unexposed group. A novel finding revealed a modest but significant correlation between DNA damage
and job seniority.
Conclusion: The study highlights the intricate relationship between occupational exposure to gasoline
components, DNA damage, and work shift lengths. Extended shifts correlate with heightened genotoxic
effects, emphasizing the importance of personalized safety measures. The significant correlation between DNA damage and job seniority introduces occupational longevity as a determinant in the genetic
health of gasoline station attendants. This discovery has implications for implementing targeted interventions and preventive strategies to safeguard workers’ genetic integrity throughout their years of
service. The study calls for further exploration of unconsidered factors in understanding the multifactorial nature of DNA damage in this occupational setting.
Creator
Rebeca I. Martínez-Salinas 1
, Irene Sánchez-Moreno 2
, Juan J. Morales López 3
,
Benito Salvatierra Izaba 2
, Everardo Barba Macías 4
, Anahí Armas-Tizapantzi 2
,
Arturo Torres-Dosal
, Irene Sánchez-Moreno 2
, Juan J. Morales López 3
,
Benito Salvatierra Izaba 2
, Everardo Barba Macías 4
, Anahí Armas-Tizapantzi 2
,
Arturo Torres-Dosal
Source
https://pdf.sciencedirectassets.com/287282/1-s2.0-S2093791124X00037/1-s2.0-S2093791124000076/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEEAaCXVzLWVhc3QtMSJHMEUCIA9NMJg5DuBLkXLfzN9GAGIO80on805mY7kyzbXkJpaPAiEAiu38v1WSe84B0uavm3burkWelembFw%2F5KjQcYTFjujUqsgUICRAFGgwwNTkwMDM1NDY4NjUiDFSkFI4xGAx0aoGGICqPBZLtyEbx3BUBbYUhZZgDQ%2Ba5vejgL9A1Qv1NtthE1YEJxVP6y36eDW9S0oyBG1fEU6GjZLZPRN9vjZB7hADHIE%2BwgnHyq3VsjCNUXGMzPdykjQ8Ws2K6pn3K2ffU8QzfXNhK94RV6WbOXom0j5goZFzz0lUN6WFpmAIOSh16gzjnlP6aXnwHHWq9m%2FwTGSNyryCW77COqed4TnHSNzQzrkgnTr0hG3vP5l0JV6dYx2pwyT7XxS4laXvYcSx5LJKXCRf7ATnYSCuNH3rQfEAzmtF7LvVKe%2FWMRreBxMpx4T%2BO8BJzpn%2Bvtp1a6jLpfewgWUEa34CfqkJgYJKozfmwZixQ71pi9heS0DLJBf5fHIIyQIJk%2FfYQCca4yT9o7NMDdNooxJso65iz0vyATJR%2B0k28oV2G%2FEvFZHZ72YoPfc2PNdhwZtUpwvt9L4vu317dY038NojaAnGzAGboXRMg4SCeg2hJHgB5pN0fa7YfCVv%2B0lcJTb4nuMrcLjrTjSioKYOZvcNPyjAMWOutNY6gzAw3rfxOgFs%2FaMyQqu6mqnNOPl9SvBz5iegMnk2satcTyD1go4NdTUfrY2Ow8txdtZMygRAUWzfVRgDgvTNMUqLaclTEaNZX9Y56i8f%2BIzBSQdr1cMWUs4YzwXWc9FkBlWgPQ74Dl0SZQLMccl7CvGUcc1C4daOGfbcAgEeT5TbW39s1C%2Fks%2Bg%2BYFpuvPueJ%2B5X3vQw4pK8Cp82wTIBjc0P%2BbKizFrRKqPedUDQE%2BlLr8kIHEeMJ2Dg8WI1h9n%2FMKBGIUuTepeiZHw8T%2B%2Fvzue7oVaLry4s9X2W9%2BBhEkAvpnSW7g%2FDZf5gTDwe4r02yzru4FQcfOjy1CK66o39D5YAwvc36zAY6sQHqBjiYxSMs6bt0apx28HCVfUc7%2BhNv7yR6Il4ZCby1lXQuvI8gVLdv02E8pfSncIHLgrD4djInN2I28bWoSsXUQWd3LLpvS2d4QZV9tfuPcDy%2F3%2B8i25maYNiLd%2Fsra2c19x0dlMg9E3ExWkq4KVloCG%2FxKSNPfdyrPDXHsfiI28TBOj8F%2FfPux2ZxjjpS6IleYFspOrfR2fTebgU2fcvmZ7jgrphEFgaEoNQAZTpACdY%3D&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Date=20260225T080949Z&X-Amz-SignedHeaders=host&X-Amz-Expires=299&X-Amz-Credential=ASIAQ3PHCVTYS6UCOPZ3%2F20260225%2Fus-east-1%2Fs3%2Faws4_request&X-Amz-Signature=97efbcc51ba863ae2eb26b91c2911162921d5b841c7ee7a1aa7e07eb6a72180e&hash=ead23c78e9c8e73945169fc3ed6f86edd3241197d76cd3f7648d32903810f748&host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&pii=S2093791124000076&tid=spdf-54217e8d-fc2e-4bab-b61a-a2bf1d4e67c8&sid=d13b8ca4630cf74d994a8ee67c879a4e16d6gxrqb&type=client&tsoh=d3d3LnNjaWVuY2VkaXJlY3QuY29t&rh=d3d3LnNjaWVuY2VkaXJlY3QuY29t&ua=0b015e065457035e50&rr=9d35b9054f257d63&cc=id
Publisher
1 Facultad de Ingeniería, Universidad de Ciencias y Artes de Chiapas (UNICACH), México
2Departamento de Salud, El Colegio de la Frontera Sur (ECOSUR), Unidad San Cristóbal, México
3 Laboratorios Institucionales de El Colegio de la Frontera Sur (ECOSUR), Unidad San Cristóbal, México
4Departamento de Ciencias de la Sustentabilidad, El Colegio de la Frontera Sur (ECOSUR), Unidad Villahermosa, México
2Departamento de Salud, El Colegio de la Frontera Sur (ECOSUR), Unidad San Cristóbal, México
3 Laboratorios Institucionales de El Colegio de la Frontera Sur (ECOSUR), Unidad San Cristóbal, México
4Departamento de Ciencias de la Sustentabilidad, El Colegio de la Frontera Sur (ECOSUR), Unidad Villahermosa, México
Date
9 February 2024
Contributor
FAJAR BAGUS W
Format
PDF
Language
ENGLISH
Type
TEXT
Files
Citation
Rebeca I. Martínez-Salinas 1
, Irene Sánchez-Moreno 2
, Juan J. Morales López 3
,
Benito Salvatierra Izaba 2
, Everardo Barba Macías 4
, Anahí Armas-Tizapantzi 2
,
Arturo Torres-Dosal, “Genotoxic Effects on Gas Station Attendants in South-southeastern
México due to Prolonged and Chronic Exposure to Gasoline,” Repository Horizon University Indonesia, accessed April 13, 2026, https://repository.horizon.ac.id/items/show/11736.
México due to Prolonged and Chronic Exposure to Gasoline,” Repository Horizon University Indonesia, accessed April 13, 2026, https://repository.horizon.ac.id/items/show/11736.