Evaluating the one‐time chair stand test for predicting the coronavirus disease severity in patients during hospital admission: a cohort study in Japan
Dublin Core
Title
Evaluating the one‐time chair stand test for predicting the coronavirus disease severity in patients during hospital admission: a cohort study in Japan
Subject
One-time chair stand test, COVID-19, Exercise-induced hypoxemia, Severity prediction
Description
Background This study aimed to understand whether the one-time chair stand test (CS-1) is useful for predicting the
severity of coronavirus disease (COVID-19) in 101 patients admitted to the hospital with acute respiratory failure.
Methods This single-centered, prospective observational cohort study enrolled 101 critically ill adult patients hos-
pitalized with COVID-19 who underwent the CS-1 as a dynamic evaluation tool in clinical practice between late April
2020 and October 2021. Data on demographic characteristics, symptoms, laboratory values, computed tomography
findings, and clinical course after admission were collected. Furthermore, the data was compared, and the association
between the intubation and non-intubation groups was determined. We also calculated the cutoff point, area under
the curve (AUC), and 95% confidence interval (CI) of the change in oxygen saturation (ΔSpO2) during the CS-1.
Results Thirty-three out of 101 patients (33%) were intubated during hospitalization. There was no significant dif-
ference in the resting SpO2 (93.3% versus 95.2%, P=0.22), but there was a significant difference in ΔSpO2 during the
CS-1 between the intubation and non-intubation groups (10.8% versus 5.5%, P<0.01). In addition, there was a signifi-
cant correlation between hospitalization and ΔSpO2 during the CS-1 (ρ=0.60, P<0.01). The generated cutoff point
was calculated as 9.5% (AUC=0.94, 95% CI=0.88–1.00).
Conclusion For COVID-19 patients with acute respiratory failure, the CS-1 performed on admission was useful for
predicting the severity of COVID-19. Furthermore, the CS-1 can be utilized as a remote and simple evaluation param-
eter. Thus, it could have potential clinical applications in the future.
severity of coronavirus disease (COVID-19) in 101 patients admitted to the hospital with acute respiratory failure.
Methods This single-centered, prospective observational cohort study enrolled 101 critically ill adult patients hos-
pitalized with COVID-19 who underwent the CS-1 as a dynamic evaluation tool in clinical practice between late April
2020 and October 2021. Data on demographic characteristics, symptoms, laboratory values, computed tomography
findings, and clinical course after admission were collected. Furthermore, the data was compared, and the association
between the intubation and non-intubation groups was determined. We also calculated the cutoff point, area under
the curve (AUC), and 95% confidence interval (CI) of the change in oxygen saturation (ΔSpO2) during the CS-1.
Results Thirty-three out of 101 patients (33%) were intubated during hospitalization. There was no significant dif-
ference in the resting SpO2 (93.3% versus 95.2%, P=0.22), but there was a significant difference in ΔSpO2 during the
CS-1 between the intubation and non-intubation groups (10.8% versus 5.5%, P<0.01). In addition, there was a signifi-
cant correlation between hospitalization and ΔSpO2 during the CS-1 (ρ=0.60, P<0.01). The generated cutoff point
was calculated as 9.5% (AUC=0.94, 95% CI=0.88–1.00).
Conclusion For COVID-19 patients with acute respiratory failure, the CS-1 performed on admission was useful for
predicting the severity of COVID-19. Furthermore, the CS-1 can be utilized as a remote and simple evaluation param-
eter. Thus, it could have potential clinical applications in the future.
Creator
Atsushi Ishihara1*, Takashi Yoshizane1,2, Teruki Mori1
, Yui Sasaki1,3, Takahiro Hosokawa4
, Jun Suzuki4
,
Akifumi Tsuzuku3
, Fumihiro Asano3 and Toshiyuki Noda2
, Yui Sasaki1,3, Takahiro Hosokawa4
, Jun Suzuki4
,
Akifumi Tsuzuku3
, Fumihiro Asano3 and Toshiyuki Noda2
Source
https://doi.org/10.1186/s12245-023-00497-x
Date
2023
Contributor
Peri Irawan
Format
pdf
Language
english
Type
text
Files
Collection
Citation
Atsushi Ishihara1*, Takashi Yoshizane1,2, Teruki Mori1
, Yui Sasaki1,3, Takahiro Hosokawa4
, Jun Suzuki4
,
Akifumi Tsuzuku3
, Fumihiro Asano3 and Toshiyuki Noda2, “Evaluating the one‐time chair stand test for predicting the coronavirus disease severity in patients during hospital admission: a cohort study in Japan,” Repository Horizon University Indonesia, accessed April 11, 2026, https://repository.horizon.ac.id/items/show/12127.