Low-dose tenecteplase during cardiopulmonary resuscitation in massive
pulmonary embolism

Low-dose tenecteplase during cardiopulmonary resuscitation in massive
pulmonary embolism

Massive pulmonary embolism, Cardiopulmonary resuscitation, Low dose Tenecteplase

Abstract
We report the case of an 18-year-old male who presented to the Emergency Department with sudden
onset dyspnea. The patient was intubated on arrival, but suffered a cardiac arrest soon after. Point-of-care
echocardiography during cardiopulmonary resuscitation revealed a grossly dilated right atrium and right
ventricle, which alerted the Emergency physician to the possibility of massive pulmonary embolism leading
to cardiac arrest. Due to no discernible history or risk factors in favour of pulmonary embolism, a decision was
taken for thrombolysis with half dose Tenecteplase. Return of spontaneous circulation was achieved 14 min after
thrombolysis, with massive pulmonary embolism subsequently being confirmed on CT Pulmonary Angiography.
Keywords Massive pulmonary embolism, Cardiopulmonary resuscitation, Low dose Tenecteplase

Farzin Vajifdar1* and Parag Badki2

https://doi.org/10.1186/s12245-024-00659-5

2024

Peri Irawan

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