Vaping‐associated illness: a reassessment
Dublin Core
Title
Vaping‐associated illness: a reassessment
Subject
Vaping, E-cigarette, Abdominal pain, Lung injury
Description
Abstract
Background In 2019, there was widespread presentation of respiratory distress as well as other organ system
involvement in patients with a history of vaping. There continue to be reports of vaping-associated illness (VAI). This
has come to be known as e-cigarette and vaping product associated lung injury (EVALI). The mechanism of injury
remains unclear.
Objectives This study reexamines the clinical characteristics of patients affected by vaping and suggests that lung
injury may not be the primary organ dysfunction but be part of a larger systemic illness.
Methods This is a retrospective chart review of all patients presenting to one hospital identified as having vaping-
associated illness
Results Fourteen patients were identified ranging in age from 15 to 33 years. Patients had a broad range of clinical
severity. Respiratory symptoms occurred in 64%, gastrointestinal symptoms in 57%, fever in 78%, neurological symp-
toms in 15% and other constitutional symptoms in 50%. 35% presented with no respiratory symptoms.
Conclusion While the lungs are certainly involved in vaping-associated illness, recognizing the extent of involve-
ment of other organ systems may provide insight into the pathophysiology of the disease. Providers should be aware
that vaping-associated illness presents with a multitude of symptoms outside of lung injury, such as abdominal pain,
headache or even fever.
Keywords Vaping, E-cigarette, Abdominal pain, Lung injury
Background In 2019, there was widespread presentation of respiratory distress as well as other organ system
involvement in patients with a history of vaping. There continue to be reports of vaping-associated illness (VAI). This
has come to be known as e-cigarette and vaping product associated lung injury (EVALI). The mechanism of injury
remains unclear.
Objectives This study reexamines the clinical characteristics of patients affected by vaping and suggests that lung
injury may not be the primary organ dysfunction but be part of a larger systemic illness.
Methods This is a retrospective chart review of all patients presenting to one hospital identified as having vaping-
associated illness
Results Fourteen patients were identified ranging in age from 15 to 33 years. Patients had a broad range of clinical
severity. Respiratory symptoms occurred in 64%, gastrointestinal symptoms in 57%, fever in 78%, neurological symp-
toms in 15% and other constitutional symptoms in 50%. 35% presented with no respiratory symptoms.
Conclusion While the lungs are certainly involved in vaping-associated illness, recognizing the extent of involve-
ment of other organ systems may provide insight into the pathophysiology of the disease. Providers should be aware
that vaping-associated illness presents with a multitude of symptoms outside of lung injury, such as abdominal pain,
headache or even fever.
Keywords Vaping, E-cigarette, Abdominal pain, Lung injury
Creator
Jonathan S. Schiffman1*
Source
https://doi.org/10.1186/s12245-024-00692-4
Date
2024
Contributor
Peri Irawan
Format
pdf
Language
english
Type
text
Files
Collection
Citation
Jonathan S. Schiffman1*, “Vaping‐associated illness: a reassessment,” Repository Horizon University Indonesia, accessed April 25, 2026, https://repository.horizon.ac.id/items/show/12411.