Peri-injury symptomatology as predictors of brain computed tomography (CT) scan abnormalities in mild traumatic brain injury (mTBI)
Dublin Core
Title
Peri-injury symptomatology as predictors of brain computed tomography (CT) scan abnormalities in mild traumatic brain injury (mTBI)
Subject
Mild TBI, Brain CT, Clinical decision rules
Description
Abstract
Objective This study aimed to identify predictors of brain CT abnormalities in patients who sustained a mild
traumatic brain injury (mTBI).
Methods Retrospective observational cohort of adult patients with mTBI (Glasgow Coma Score 13–15) that occurred
within the preceding 24 h.
Results 2548 (91%) of the cohort had a brain CT and 698 (27%) demonstrated abnormal findings. The most
frequently observed CT abnormalities were bleeding (638, 25%) and fractures (190, 7.4%). Multivariate logistic
regression analysis revealed several significant predictors associated with the presence of brain CT abnormalities
including older age [P<0.0001], male sex [P<0.0001], loss of consciousness [P=0.0041], associated vomiting
[P=0.0011], alteration of consciousness (AOC) [P=0102], and GCS score [P<0.0001]. This was a robust model with an
R2 of 14.2%.
Conclusion In this retrospective analysis, older age, male sex, the presence of loss of consciousness or alteration
in consciousness, lower GCS score, and associated vomiting were found to be significant predictors of having an
abnormal brain CT. These findings highlight the importance of considering these factors when determining the
necessity of brain CT scans in patients with mTBI and suggest that existing clinical decision rules may be limited.
These findings may also help to inform clinical decision rules. Early identification of individuals at a higher risk of CT
abnormalities may assist in appropriate management and allocation of healthcare resources.
Keywords Mild TBI, Brain CT, Clinical decision rules
Objective This study aimed to identify predictors of brain CT abnormalities in patients who sustained a mild
traumatic brain injury (mTBI).
Methods Retrospective observational cohort of adult patients with mTBI (Glasgow Coma Score 13–15) that occurred
within the preceding 24 h.
Results 2548 (91%) of the cohort had a brain CT and 698 (27%) demonstrated abnormal findings. The most
frequently observed CT abnormalities were bleeding (638, 25%) and fractures (190, 7.4%). Multivariate logistic
regression analysis revealed several significant predictors associated with the presence of brain CT abnormalities
including older age [P<0.0001], male sex [P<0.0001], loss of consciousness [P=0.0041], associated vomiting
[P=0.0011], alteration of consciousness (AOC) [P=0102], and GCS score [P<0.0001]. This was a robust model with an
R2 of 14.2%.
Conclusion In this retrospective analysis, older age, male sex, the presence of loss of consciousness or alteration
in consciousness, lower GCS score, and associated vomiting were found to be significant predictors of having an
abnormal brain CT. These findings highlight the importance of considering these factors when determining the
necessity of brain CT scans in patients with mTBI and suggest that existing clinical decision rules may be limited.
These findings may also help to inform clinical decision rules. Early identification of individuals at a higher risk of CT
abnormalities may assist in appropriate management and allocation of healthcare resources.
Keywords Mild TBI, Brain CT, Clinical decision rules
Creator
Sihi Vasista1
, Josue Saint-Fleur2
, Neera Kapoor3
and Latha Ganti2,4*
, Josue Saint-Fleur2
, Neera Kapoor3
and Latha Ganti2,4*
Source
https://doi.org/10.1186/s12245-024-00754-7
Date
2024
Contributor
Peri Irawan
Format
PDF
Language
ENGLISH
Type
TEXT
Files
Collection
Citation
Sihi Vasista1
, Josue Saint-Fleur2
, Neera Kapoor3
and Latha Ganti2,4*, “Peri-injury symptomatology as predictors of brain computed tomography (CT) scan abnormalities in mild traumatic brain injury (mTBI),” Repository Horizon University Indonesia, accessed April 26, 2026, https://repository.horizon.ac.id/items/show/12524.