Stroke in the young: infective endocarditis due to mitral valve prolapse leading to acute ischemic stroke and subsequent hemorrhagic transformation
Dublin Core
Title
Stroke in the young: infective endocarditis due to mitral valve prolapse leading to acute ischemic stroke and subsequent hemorrhagic transformation
Subject
Mitral valve prolapse, Infective endocarditis, Acute ischemic stroke
Description
Abstract
Background Stroke in young needs an individualized approach before considering thrombolysis. Here we present
a case of undiagnosed mitral valve prolapse presenting with stroke due to associated infective endocarditis. Young
stroke patients presenting with fever need a panoramic approach.
Case summary This 39-year-old female with a background history of fever and loss of weight for two months
presented to the emergency department with a history of altered sensorium and aphasia. The Magnetic Resonance
Imaging (MRI) showed a hyperacute infarct. Hence, thrombolysis with alteplase was considered. Post thrombolysis,
the patient had a parenchymal bleed. The diagnostic evaluation yielded stroke secondary to infective endocarditis
because of undiagnosed mitral valve prolapse.
Conclusion Mitral valve prolapse is not associated with stroke in young patients. However, the undiagnosed infec-
tive endocarditis and subsequent septic emboli led to an increased risk. Emergency physicians and intensivists should
anticipate infective causes before considering thrombolysis, as the results could be counterproductive.
Keywords Mitral valve prolapse, Infective endocarditis, Acute ischemic stroke
Background Stroke in young needs an individualized approach before considering thrombolysis. Here we present
a case of undiagnosed mitral valve prolapse presenting with stroke due to associated infective endocarditis. Young
stroke patients presenting with fever need a panoramic approach.
Case summary This 39-year-old female with a background history of fever and loss of weight for two months
presented to the emergency department with a history of altered sensorium and aphasia. The Magnetic Resonance
Imaging (MRI) showed a hyperacute infarct. Hence, thrombolysis with alteplase was considered. Post thrombolysis,
the patient had a parenchymal bleed. The diagnostic evaluation yielded stroke secondary to infective endocarditis
because of undiagnosed mitral valve prolapse.
Conclusion Mitral valve prolapse is not associated with stroke in young patients. However, the undiagnosed infec-
tive endocarditis and subsequent septic emboli led to an increased risk. Emergency physicians and intensivists should
anticipate infective causes before considering thrombolysis, as the results could be counterproductive.
Keywords Mitral valve prolapse, Infective endocarditis, Acute ischemic stroke
Creator
Kajal Arora1 and Amarja Ashok Havaldar1*
Source
https://doi.org/10.1186/s12245-024-00755-6
Date
2024
Contributor
Peri Irawan
Format
PDF
Language
ENGLIST
Type
TEXT
Files
Collection
Citation
Kajal Arora1 and Amarja Ashok Havaldar1*, “Stroke in the young: infective endocarditis due to mitral valve prolapse leading to acute ischemic stroke and subsequent hemorrhagic transformation,” Repository Horizon University Indonesia, accessed April 11, 2026, https://repository.horizon.ac.id/items/show/12526.