Factors associated with severity and length of hospital stay in patients with acute upper gastrointestinal bleeding: insights from two Ethiopian hospitals
Dublin Core
Title
Factors associated with severity and length of hospital stay in patients with acute upper gastrointestinal bleeding: insights from two Ethiopian hospitals
Subject
Upper gastrointestinal bleeding, Disease severity, Length of hospital stay, Hematemesis, Esophageal
varices, Duodenal ulcers
varices, Duodenal ulcers
Description
Abstract
Background Upper gastrointestinal bleeding (UGIB) is a critical emergency with substantial morbidity and mortality.
Outcomes depend on bleeding severity, patient risk factors, and comorbidities. This study evaluated clinical patterns
and factors influencing disease severity and hospital stay among patients present with UGIB symptoms at two major
Ethiopian hospitals.
Methods A retrospective, cross-sectional review was conducted on 199 UGIB patients admitted to Yekatit 12 Hospital
Medical College (Y12HMC) and Tikur Anbesa Specialized Hospital (TASH) from September 2022 to September 2023.
Data on demographics, clinical presentations, endoscopic findings, and outcomes were analyzed using SPSS version
26. Binary logistic regression assessed associations, with statistical significance set at P<0.05.
Results Of 199 patients, 70.9% were male, predominantly aged 18–40. Hematemesis (63.8%) and hematemesis with
melena (27.6%) were common presentations. Endoscopy was not performed on more than half of the participants,
with 116 patients (58.3%) not undergoing this procedure. Among the 83 cases who did have endoscopy, esophageal
varices emerged as the most common condition, observed in 43.3% (36 cases. Smoking (AOR=1.77), alcohol intake
(AOR=1.89), and drug use (AOR=1.34) were linked to higher severity scores. Alcohol use, comorbidities, liver disease,
and previous drug use correlated with prolonged hospital stays.
Conclusion UGIB predominantly affects younger males, with hematemesis as the primary presentation. Key factors
like smoking, alcohol intake, and drug use were associated with greater disease severity and longer hospital stays.
These findings suggest the importance of lifestyle interventions, particularly in resource-limited settings.
Keywords Upper gastrointestinal bleeding, Disease severity, Length of hospital stay, Hematemesis, Esophageal
varices, Duodenal ulcers
Background Upper gastrointestinal bleeding (UGIB) is a critical emergency with substantial morbidity and mortality.
Outcomes depend on bleeding severity, patient risk factors, and comorbidities. This study evaluated clinical patterns
and factors influencing disease severity and hospital stay among patients present with UGIB symptoms at two major
Ethiopian hospitals.
Methods A retrospective, cross-sectional review was conducted on 199 UGIB patients admitted to Yekatit 12 Hospital
Medical College (Y12HMC) and Tikur Anbesa Specialized Hospital (TASH) from September 2022 to September 2023.
Data on demographics, clinical presentations, endoscopic findings, and outcomes were analyzed using SPSS version
26. Binary logistic regression assessed associations, with statistical significance set at P<0.05.
Results Of 199 patients, 70.9% were male, predominantly aged 18–40. Hematemesis (63.8%) and hematemesis with
melena (27.6%) were common presentations. Endoscopy was not performed on more than half of the participants,
with 116 patients (58.3%) not undergoing this procedure. Among the 83 cases who did have endoscopy, esophageal
varices emerged as the most common condition, observed in 43.3% (36 cases. Smoking (AOR=1.77), alcohol intake
(AOR=1.89), and drug use (AOR=1.34) were linked to higher severity scores. Alcohol use, comorbidities, liver disease,
and previous drug use correlated with prolonged hospital stays.
Conclusion UGIB predominantly affects younger males, with hematemesis as the primary presentation. Key factors
like smoking, alcohol intake, and drug use were associated with greater disease severity and longer hospital stays.
These findings suggest the importance of lifestyle interventions, particularly in resource-limited settings.
Keywords Upper gastrointestinal bleeding, Disease severity, Length of hospital stay, Hematemesis, Esophageal
varices, Duodenal ulcers
Creator
Missgana Worku Belete1
, Molla Asnake Kebede2*, Meaza Rorisa Bedane3
, Trhas Tadesse Berhe4
, Alemayehu
Beharu Tekle5
, Erkihun Pawlos Shash1
, Misikr Alemu Eshetu1
, Girma Daniel Bushiso2
and Biruk Yacob Loge6
, Molla Asnake Kebede2*, Meaza Rorisa Bedane3
, Trhas Tadesse Berhe4
, Alemayehu
Beharu Tekle5
, Erkihun Pawlos Shash1
, Misikr Alemu Eshetu1
, Girma Daniel Bushiso2
and Biruk Yacob Loge6
Source
https://doi.org/10.1186/s12245-024-00768-1
Date
2024
Contributor
Peri Irawan
Format
PDF
Language
ENGLISH
Type
TEXT
Files
Collection
Citation
Missgana Worku Belete1
, Molla Asnake Kebede2*, Meaza Rorisa Bedane3
, Trhas Tadesse Berhe4
, Alemayehu
Beharu Tekle5
, Erkihun Pawlos Shash1
, Misikr Alemu Eshetu1
, Girma Daniel Bushiso2
and Biruk Yacob Loge6, “Factors associated with severity and length of hospital stay in patients with acute upper gastrointestinal bleeding: insights from two Ethiopian hospitals,” Repository Horizon University Indonesia, accessed April 12, 2026, https://repository.horizon.ac.id/items/show/12533.