Successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning: a case report
Dublin Core
Title
Successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning: a case report
Subject
TCA, Plasmapheresis, Intralipid
Description
Abstract
Objective Tricyclic antidepressants (TCAs) are used to treat depression, but if abused or misused, they can cause
poisoning, which can be fatal. The main treatment for TCA poisoning is administering sodium bicarbonate.
Methods We report a 16-year-old girl diagnosed with nortriptyline poisoning with a profound neurologic and
cardiovascular manifestations, successfully treated using sodium bicarbonate, intralipid emulsion, and plasmapheresis.
Conclusions Plasmapheresis can be a good treatment modality for patients with TCA poisoning who do not respond
well to classic treatments.
Keywords TCA, Plasmapheresis, Intralipid
Objective Tricyclic antidepressants (TCAs) are used to treat depression, but if abused or misused, they can cause
poisoning, which can be fatal. The main treatment for TCA poisoning is administering sodium bicarbonate.
Methods We report a 16-year-old girl diagnosed with nortriptyline poisoning with a profound neurologic and
cardiovascular manifestations, successfully treated using sodium bicarbonate, intralipid emulsion, and plasmapheresis.
Conclusions Plasmapheresis can be a good treatment modality for patients with TCA poisoning who do not respond
well to classic treatments.
Keywords TCA, Plasmapheresis, Intralipid
Creator
Asma Ahmadinejad1
, Amir Saeed2
and Marzieh Davoodi3*
, Amir Saeed2
and Marzieh Davoodi3*
Source
https://doi.org/10.1186/s12245-025-00824-4
Date
2025
Contributor
Peri Irawan
Format
pdf
Language
english
Type
text
Files
Collection
Citation
Asma Ahmadinejad1
, Amir Saeed2
and Marzieh Davoodi3*, “Successful outcome following intralipid emulsion and plasmapheresis in a patient with profound neurologic and cardiovascular manifestations due to nortriptyline poisoning: a case report,” Repository Horizon University Indonesia, accessed April 25, 2026, https://repository.horizon.ac.id/items/show/12650.