Incidence of and risk factors for mortality in children with mushroom poisoning

Incidence of and risk factors for mortality in children with mushroom poisoning

Incidence, Risk factors, Mushroom poisoning, Mortality, Children

Abstract
Objective We aimed to evaluate the incidence of and risk factors for mortality in children with mushroom poisoning.
Methods Sixty-seven children with mushroom poisoning who were hospitalized at the Children’s Hospital of
Chongqing Medical University were retrospectively enrolled. The clinical characteristics of the children in the surviving
and non-surviving groups were compared. Variables with a P value<0.1 in the univariate logistic regression analysis
were included in the multivariate logistic regression analysis. A receiver operating characteristic (ROC) curve was
generated to determine the optimal cutoff point.
Results The mortality rate of children with mushroom poisoning was 23.88% (16/67), and the incidence of death
during hospitalization was 35.02 per 1,000 person-days. The median pediatric sequential organ failure assessment
(pSOFA) score was 1.00 (interquartile range [IQR] 0.00–3.00). Logistic regression analysis revealed that the pSOFA score
was independently associated with mortality (odds ratio [OR] 4.92, 95% confidence interval [CI] 1.59–62.21; P=0.040).
The optimal cutoff point of the pSOFA score for predicting mortality was 2.00, with an area under the curve (AUC) of
0.84 (95% CI 0.71–0.88, P<0.001*).
Conclusions In this study, the incidence of death among children with mushroom poisoning was retrospectively
evaluated. The pSOFA score may serve as a good prognostic indicator in children with mushroom poisoning, and
children with a pSOFA score≥2 have a significantly increased risk of mortality.
Keywords Incidence, Risk factors, Mushroom poisoning, Mortality, Children

Jie Cheng1
, Ya Liu2
, Shaojun Li1
, Kaibin Pu1
, Junming Huo3

and Liping Tan1*

https://doi.org/10.1186/s12245-025-00906-3

2025

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