Jurnal internasional Afrika vol.11 issue 4 2021
African Journal of Emergency Medicine
Survival status and predictors of mortality among traumatic brain injury patients in an Ethiopian hospital: A retrospective cohort study
Dublin Core
Title
Jurnal internasional Afrika vol.11 issue 4 2021
African Journal of Emergency Medicine
Survival status and predictors of mortality among traumatic brain injury patients in an Ethiopian hospital: A retrospective cohort study
African Journal of Emergency Medicine
Survival status and predictors of mortality among traumatic brain injury patients in an Ethiopian hospital: A retrospective cohort study
Subject
Traumatic brain injury
Glasgow coma scale
Survival status
Bahir Dar
Glasgow coma scale
Survival status
Bahir Dar
Description
Introduction: Traumatic brain injury is a major global public health problem causing substantial mortality among
the adult population. Hence, this study aimed to determine the predictors of mortality among adult traumatic
brain injury patients in Felegehiwot Comprehensive Specialized Hospital in Northwest Ethiopia during 2020.
Methods: A retrospective cohort study was conducted at Felegehiwot Comprehensive Specialized Hospital using
anonymized patient data obtained from chart review. Descriptive statistics were used to summarise the patient
characteristics. The Kaplan–Meier survival curve and log-rank test were used to test for differences in survival
status among groups. The Cox proportional hazards regression model was used at the 5% level of significance to
determine the net effect of each explanatory variable on time to death.
Results: In total, 338 patients aged ≥15 years and diagnosed with traumatic brain injury were included in the
analysis. Among these patients, 103 (30.45%) died, giving a crude death rate of 25.53 per 1000 (95% CI:
21.05–30.98) person-days of follow-up. The overall median survival time was 44 days. The independent pre-
dictors of mortality after diagnosis of traumatic brain injury were admission Glasgow coma scale score ≤ 8
(adjusted hazard ratio (AHR): 4.85; 95% confidence interval (CI): 1.73–13.62), bilateral non-reactive pupils at
admission (AHR: 2.00 (95% CI: 1.10–3.71), elevated systolic blood pressure at admission (AHR: 0.31; 95%
CI:0.11–0.86), elevated diastolic blood pressure at admission (AHR: 3.54; 95% CI: 1.33–9.43), and haematoma
evacuation (AHR: 0.42; 95% CI: 0.16–0.90).
Discussion: The Survival status of traumatic brain injury patients was relatively low in this study. Glasgow coma
scale score, bilateral non-reactive pupils, and elevated blood pressure were significant predictors of mortality.
Further prospective follow-up studies that include residence and occupation are recommended.
the adult population. Hence, this study aimed to determine the predictors of mortality among adult traumatic
brain injury patients in Felegehiwot Comprehensive Specialized Hospital in Northwest Ethiopia during 2020.
Methods: A retrospective cohort study was conducted at Felegehiwot Comprehensive Specialized Hospital using
anonymized patient data obtained from chart review. Descriptive statistics were used to summarise the patient
characteristics. The Kaplan–Meier survival curve and log-rank test were used to test for differences in survival
status among groups. The Cox proportional hazards regression model was used at the 5% level of significance to
determine the net effect of each explanatory variable on time to death.
Results: In total, 338 patients aged ≥15 years and diagnosed with traumatic brain injury were included in the
analysis. Among these patients, 103 (30.45%) died, giving a crude death rate of 25.53 per 1000 (95% CI:
21.05–30.98) person-days of follow-up. The overall median survival time was 44 days. The independent pre-
dictors of mortality after diagnosis of traumatic brain injury were admission Glasgow coma scale score ≤ 8
(adjusted hazard ratio (AHR): 4.85; 95% confidence interval (CI): 1.73–13.62), bilateral non-reactive pupils at
admission (AHR: 2.00 (95% CI: 1.10–3.71), elevated systolic blood pressure at admission (AHR: 0.31; 95%
CI:0.11–0.86), elevated diastolic blood pressure at admission (AHR: 3.54; 95% CI: 1.33–9.43), and haematoma
evacuation (AHR: 0.42; 95% CI: 0.16–0.90).
Discussion: The Survival status of traumatic brain injury patients was relatively low in this study. Glasgow coma
scale score, bilateral non-reactive pupils, and elevated blood pressure were significant predictors of mortality.
Further prospective follow-up studies that include residence and occupation are recommended.
Creator
Abraham Tsedalu Amare , Tadesse Dagget Tesfaye , Awole Seid Ali , Tamiru Alene Woelile , Tekalign Amera Birlie , Worku Misganew Kebede , Sheganew Fetene Tassew , Ermias Sisay Chanie , Dejen Getaneh Feleke
Source
https://doi.org/10.1016/j.afjem.2021.06.003
Date
1 June 2021
Contributor
peri irawan
Format
pdf
Language
english
Type
text
Files
Citation
Abraham Tsedalu Amare , Tadesse Dagget Tesfaye , Awole Seid Ali , Tamiru Alene Woelile , Tekalign Amera Birlie , Worku Misganew Kebede , Sheganew Fetene Tassew , Ermias Sisay Chanie , Dejen Getaneh Feleke, “Jurnal internasional Afrika vol.11 issue 4 2021
African Journal of Emergency Medicine
Survival status and predictors of mortality among traumatic brain injury patients in an Ethiopian hospital: A retrospective cohort study,” Repository Horizon University Indonesia, accessed September 20, 2024, https://repository.horizon.ac.id/items/show/1857.
African Journal of Emergency Medicine
Survival status and predictors of mortality among traumatic brain injury patients in an Ethiopian hospital: A retrospective cohort study,” Repository Horizon University Indonesia, accessed September 20, 2024, https://repository.horizon.ac.id/items/show/1857.