Safety and Health at Work Vol. 10 Issue 2 2019
Workplace Diesel Exhausts and Gasoline Exposure and Risk of Colorectal Cancer in Four Nordic Countries (Original Article)
Dublin Core
Title
Safety and Health at Work Vol. 10 Issue 2 2019
Workplace Diesel Exhausts and Gasoline Exposure and Risk of Colorectal Cancer in Four Nordic Countries (Original Article)
Workplace Diesel Exhausts and Gasoline Exposure and Risk of Colorectal Cancer in Four Nordic Countries (Original Article)
Subject
Caseecontrol study, Colorectal cancer, Diesel exhaust, Gasoline, Workplace
Description
Background: Evidence on associations between occupational diesel exhaust and gasoline exposure and colorectal cancer is limited. We aimed to assess the effect of workplace exposure to diesel exhaust and gasoline on the risk of colorectal cancer.
Methods: This caseecontrol study included 181,709 colon cancer and 109,227 rectal cancer cases diag-
nosed between 1961 and 2005 in Finland, Iceland, Norway, and Sweden. Cases and controls were
identified from the Nordic Occupational Cancer Study cohort and matched for country, birth year, and sex. Diesel exhaust and gasoline exposure values were assigned by country-specific job-exposure matrices. Odds ratios and 95% confidence intervals were calculated by using conditional logistic regression models. The results were adjusted for physical strain at work and occupational exposure to benzene, formaldehyde, ionizing radiation, chlorinated hydrocarbons, chromium, and wood dust.
Results: Diesel exhaust exposure was associated with a small increase in the risk of rectal cancer (odds ratio 1⁄4 1.05, 95% confidence interval 1.02-1.08). Gasoline exposure was not associated with colorectal cancer risk.
Conclusion: This study showed a small risk increase for rectal cancer after workplace diesel exhaust
exposure. However, this finding could be due to chance, given the limitations of the study.
Methods: This caseecontrol study included 181,709 colon cancer and 109,227 rectal cancer cases diag-
nosed between 1961 and 2005 in Finland, Iceland, Norway, and Sweden. Cases and controls were
identified from the Nordic Occupational Cancer Study cohort and matched for country, birth year, and sex. Diesel exhaust and gasoline exposure values were assigned by country-specific job-exposure matrices. Odds ratios and 95% confidence intervals were calculated by using conditional logistic regression models. The results were adjusted for physical strain at work and occupational exposure to benzene, formaldehyde, ionizing radiation, chlorinated hydrocarbons, chromium, and wood dust.
Results: Diesel exhaust exposure was associated with a small increase in the risk of rectal cancer (odds ratio 1⁄4 1.05, 95% confidence interval 1.02-1.08). Gasoline exposure was not associated with colorectal cancer risk.
Conclusion: This study showed a small risk increase for rectal cancer after workplace diesel exhaust
exposure. However, this finding could be due to chance, given the limitations of the study.
Creator
Madar Talibov, Jorma Sormunen, Elisabete Weiderpass, Kristina Kjaerheim, Jan-Ivar Martinsen, Per Sparen , Laufey Tryggvadottir, Johnni Hansen, Eero Pukkala
Publisher
Elsevier Korea LLC
Date
June 2019
Contributor
Sri Wahyuni
Format
PDF
Language
English
Type
Text
Coverage
Safety and Health at Work Vol. 10 Issue 2 2019
Files
Citation
Madar Talibov, Jorma Sormunen, Elisabete Weiderpass, Kristina Kjaerheim, Jan-Ivar Martinsen, Per Sparen , Laufey Tryggvadottir, Johnni Hansen, Eero Pukkala, “Safety and Health at Work Vol. 10 Issue 2 2019
Workplace Diesel Exhausts and Gasoline Exposure and Risk of Colorectal Cancer in Four Nordic Countries (Original Article),” Repository Horizon University Indonesia, accessed April 4, 2025, https://repository.horizon.ac.id/items/show/1927.
Workplace Diesel Exhausts and Gasoline Exposure and Risk of Colorectal Cancer in Four Nordic Countries (Original Article),” Repository Horizon University Indonesia, accessed April 4, 2025, https://repository.horizon.ac.id/items/show/1927.