Safety and Health at Work Vol. 13 Issue 2 2022
Comparison of Overall Immunity Levels among Workers at Grape Orchard, Rose Greenhouse, and Open-Field Onion Farm (Original article)
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Title
Safety and Health at Work Vol. 13 Issue 2 2022
Comparison of Overall Immunity Levels among Workers at Grape Orchard, Rose Greenhouse, and Open-Field Onion Farm (Original article)
Comparison of Overall Immunity Levels among Workers at Grape Orchard, Rose Greenhouse, and Open-Field Onion Farm (Original article)
Subject
Cytokines, Agricultural workers, Immunity, Immunoglobulins, Natural killer cell
Description
Background: Occupational hazards in crop farms vary diversely based on different field operations as soil management, harvesting processes, pesticide, or fertilizer application. We aimed at evaluating the
immunological status of crop farmers, as limited systematic investigations on immune alteration involved with crop farming have been reported yet.
Methods: Immunological parameters including plasma immunoglobulin level, major peripheral immune cells distribution, and level of cytokine production from activated T cell were conducted. Nineteen grape
orchard, 48 onion open-field, and 21 rose greenhouse farmers were participated.
Results: Significantly low proportion of natural killer (NK) cell, a core cell for innate immunity, was revealed in the grape farmers (19.8 3.3%) in comparison to the onion farmers (26.4 3.1%) and the rose farmers (26.9 2.5%), whereas cytotoxic T lymphocyte proportion was lower in the grape and the onion farmers than the rose farmers. The proportion of NKT cell, an immune cell implicated with allergic response, was significantly higher in the grape (2.3 0.3%) and the onion (1.6 0.8%) farmers compared with the rose farmers (1.0 0.4%). A significantly decreased interferon-gamma:interleukin-13 ratio was observed from ex vivo stimulated peripheral blood mononuclear cells of grape farmers compared with the other two groups. The grape farmers revealed the lowest levels of plasma IgG1 and IgG4, and their plasma IgE level was not significantly different from that of the onion or the rose farmers.
Conclusion: Our finding suggests the high vulnerability of workplace-mediated allergic immunity in grape orchard farmers followed by open-field onion farmers and then the rose greenhouse farmers.
immunological status of crop farmers, as limited systematic investigations on immune alteration involved with crop farming have been reported yet.
Methods: Immunological parameters including plasma immunoglobulin level, major peripheral immune cells distribution, and level of cytokine production from activated T cell were conducted. Nineteen grape
orchard, 48 onion open-field, and 21 rose greenhouse farmers were participated.
Results: Significantly low proportion of natural killer (NK) cell, a core cell for innate immunity, was revealed in the grape farmers (19.8 3.3%) in comparison to the onion farmers (26.4 3.1%) and the rose farmers (26.9 2.5%), whereas cytotoxic T lymphocyte proportion was lower in the grape and the onion farmers than the rose farmers. The proportion of NKT cell, an immune cell implicated with allergic response, was significantly higher in the grape (2.3 0.3%) and the onion (1.6 0.8%) farmers compared with the rose farmers (1.0 0.4%). A significantly decreased interferon-gamma:interleukin-13 ratio was observed from ex vivo stimulated peripheral blood mononuclear cells of grape farmers compared with the other two groups. The grape farmers revealed the lowest levels of plasma IgG1 and IgG4, and their plasma IgE level was not significantly different from that of the onion or the rose farmers.
Conclusion: Our finding suggests the high vulnerability of workplace-mediated allergic immunity in grape orchard farmers followed by open-field onion farmers and then the rose greenhouse farmers.
Creator
Anju Maharjan, Ravi Gautam, JiHun Jo, Manju Acharya, DaEun Lee, Pramod Bahadur K C, Jin Gim, Sojung Sin, Hyocher Kim, ChangYul Kim,
SooYeon Lee, SooJin Lee, Yong Heo, HyoungAh Kim
SooYeon Lee, SooJin Lee, Yong Heo, HyoungAh Kim
Publisher
Elsevier Korea LLC
Date
June 2022
Contributor
Sri Wahyuni
Format
PDF
Language
English
Type
Text
Coverage
Safety and Health at Work Vol. 13 Issue 2 2022
Files
Citation
Anju Maharjan, Ravi Gautam, JiHun Jo, Manju Acharya, DaEun Lee, Pramod Bahadur K C, Jin Gim, Sojung Sin, Hyocher Kim, ChangYul Kim,
SooYeon Lee, SooJin Lee, Yong Heo, HyoungAh Kim , “Safety and Health at Work Vol. 13 Issue 2 2022
Comparison of Overall Immunity Levels among Workers at Grape Orchard, Rose Greenhouse, and Open-Field Onion Farm (Original article),” Repository Horizon University Indonesia, accessed February 5, 2025, https://repository.horizon.ac.id/items/show/2262.
Comparison of Overall Immunity Levels among Workers at Grape Orchard, Rose Greenhouse, and Open-Field Onion Farm (Original article),” Repository Horizon University Indonesia, accessed February 5, 2025, https://repository.horizon.ac.id/items/show/2262.