Safety and Health at Work Vol. 13 Supplement 1 2022
Occupational exposure and lung function decline in population-based studies: a systematic review and meta-analysis

Dublin Core

Title

Safety and Health at Work Vol. 13 Supplement 1 2022
Occupational exposure and lung function decline in population-based studies: a systematic review and meta-analysis

Subject

Occupational exposure, lung function decline

Description

Introduction/Aim: Occupational exposures can accelerate age-related lung function decline. Some population-based longitudinal studies have investigated this association. However, the evidence has not been systematically synthesized.
Methods: Ovid Medline, PubMed, Embase via Ovid, and Web of Science were searched using keywords and text words related to occupational exposure and lung function and 12 studies identified using pre-defined inclusion criteria. The quality of the studies was assessed and fixed and random-effect meta-analysis including four studies performed. The heterogeneity was assessed using the I2 test, and publication bias was evaluated using funnel plots. The review was registered with PROSPERO (CRD42020154227).
Results: Ever exposure to gases/fumes and vapours, gas, dust or fumes (VGDF) was associated with FEV1 decline. Ever exposure to fungicides and aromatic solvents was associated with lung function decline (FEV1). No significant association was observed between exposures to biological dust, mineral dust, herbicides, insecticides, and metals. Cumulative exposure to gases/fumes and fungicides was found to be associated with lung function in most of the studies. However, this was not included in the meta-analysis, due to inconsistent reporting of the outcomes across the studies.
Conclusion: Pooled estimates from population-based studies have provided evidence that several occupational exposures were associated with lung function decline. Both exposure controls in relevant jobs and respiratory health surveillance are required to protect the lung health of workers in these industries.

Creator

Golam Rabbani, Naima Nimmi, Geza Benke, Shyamali Dharmage, Dinh Bui, Malcolm Sim, Michael Abramson, Sheikh Alif

Publisher

Elsevier Korea LLC

Date

January 2022

Contributor

Sri Wahyuni

Format

PDF

Language

English

Type

Text

Coverage

Safety and Health at Work Vol. 13 Supplement 1 2022

Files

Tags

,Repository, Repository Horizon University Indonesia, Repository Universitas Horizon Indonesia, Horizon.ac.id, Horizon University Indonesia, Universitas Horizon Indonesia, HorizonU, Repo Horizon , ,Repository, Repository Horizon University Indonesia, Repository Universitas Horizon Indonesia, Horizon.ac.id, Horizon University Indonesia, Universitas Horizon Indonesia, HorizonU, Repo Horizon ,

Citation

Golam Rabbani, Naima Nimmi, Geza Benke, Shyamali Dharmage, Dinh Bui, Malcolm Sim, Michael Abramson, Sheikh Alif, “Safety and Health at Work Vol. 13 Supplement 1 2022
Occupational exposure and lung function decline in population-based studies: a systematic review and meta-analysis,” Repository Horizon University Indonesia, accessed April 3, 2025, https://repository.horizon.ac.id/items/show/2354.