Safety and Health at Work Vol. 13 Supplement 2022
Biological exposure monitoring after massive chemical disasters
Dublin Core
Title
Safety and Health at Work Vol. 13 Supplement 2022
Biological exposure monitoring after massive chemical disasters
Biological exposure monitoring after massive chemical disasters
Subject
Biological exposure monitoring, massive chemical disasters
Description
Introduction: Exposure biomonitoring may be useful in chemical accidents and disasters for triage and acute treatment, addressing
worries among affected subjects, and for follow up of long-term health effects. Here, an approach to identify for which substances. biomonitoring would be most useful in disasters is presented, using
Sweden as an example.
Method: In 2014-6, a group of experts in Sweden identified 83 industrial chemicals that could (if released in air) acutely and severely affect many people’s health, and therefore be a burden on emergency and health services. The identification was based on estimated annual use, physical properties, reactivity, toxicity. For this presentation, I compiled data on biomonitoring methods and biomarker half times.
Results: Biomonitoring methods were readily available for 25 of the 83 chemicals. For these 25, use ranged from 10^7 to <1 tonne/y and the half time from months to hours. Long half times are obviously an advantage, however biomarkers with short half times are also valuable for reverse dosimetry, given that the times of exposure and sampling are known.
Conclusions: Compilation of relevant data may help identify priority areas for biomonitoring preparedness in chemical accidents and disasters. For substances of high concern and with biomonitoring methods available, actions should be taken to improve disaster preparedness, including e.g. descriptions of sampling procedures, sample treatment and storage, analytical methods, and where to send the samples. For substances presently lacking suitable biomonitoring methods, the possibility to develop a method should be investigated.
worries among affected subjects, and for follow up of long-term health effects. Here, an approach to identify for which substances. biomonitoring would be most useful in disasters is presented, using
Sweden as an example.
Method: In 2014-6, a group of experts in Sweden identified 83 industrial chemicals that could (if released in air) acutely and severely affect many people’s health, and therefore be a burden on emergency and health services. The identification was based on estimated annual use, physical properties, reactivity, toxicity. For this presentation, I compiled data on biomonitoring methods and biomarker half times.
Results: Biomonitoring methods were readily available for 25 of the 83 chemicals. For these 25, use ranged from 10^7 to <1 tonne/y and the half time from months to hours. Long half times are obviously an advantage, however biomarkers with short half times are also valuable for reverse dosimetry, given that the times of exposure and sampling are known.
Conclusions: Compilation of relevant data may help identify priority areas for biomonitoring preparedness in chemical accidents and disasters. For substances of high concern and with biomonitoring methods available, actions should be taken to improve disaster preparedness, including e.g. descriptions of sampling procedures, sample treatment and storage, analytical methods, and where to send the samples. For substances presently lacking suitable biomonitoring methods, the possibility to develop a method should be investigated.
Creator
Gunnar Johanson
Publisher
Elsevier Korea LLC
Date
January 2022
Contributor
Sri Wahyuni
Format
PDF
Language
English
Type
Text
Coverage
Safety and Health at Work Vol. 13 Supplement 2022
Files
Citation
Gunnar Johanson, “Safety and Health at Work Vol. 13 Supplement 2022
Biological exposure monitoring after massive chemical disasters,” Repository Horizon University Indonesia, accessed November 21, 2024, https://repository.horizon.ac.id/items/show/2398.
Biological exposure monitoring after massive chemical disasters,” Repository Horizon University Indonesia, accessed November 21, 2024, https://repository.horizon.ac.id/items/show/2398.