Jurnal Internasional Afrika vol. 11 issue 1 2021
African Journal of Emergency Medicine
Prevalence and risk factors of acute kidney injury in polytrauma patients at Muhimbili Orthopedic Institute, Tanzania
Dublin Core
Title
Jurnal Internasional Afrika vol. 11 issue 1 2021
African Journal of Emergency Medicine
Prevalence and risk factors of acute kidney injury in polytrauma patients at Muhimbili Orthopedic Institute, Tanzania
African Journal of Emergency Medicine
Prevalence and risk factors of acute kidney injury in polytrauma patients at Muhimbili Orthopedic Institute, Tanzania
Subject
Polytrauma
Acute kidney injury
Muhimbili Orthopedic Institute
Tanzania
Acute kidney injury
Muhimbili Orthopedic Institute
Tanzania
Description
Background: Polytrauma can lead to multi-organ dysfunction in addition to the local injuries. Acute kidney injury
(AKI) is one of the most common causes and contributors to the high morbidity and mortality. Prevalence of
acute kidney injury in trauma patients is as reported to be as high as 40.3%. Early detection and management
leads to better outcomes. The prevalence of AKI among polytrauma patients remains unknown in our setting.
Methodology: A cross-sectional study involving all adults with polytrauma who presented at the emergency
department at Muhimbili Orthopedic Institute (MOI) was designed. A score of ≥18 on the New Injury Severity
Score (NISS) screening tool was used to identify polytrauma patients. The Kidney Disease Improving Global
Outcomes (KDIGO) criteria was used to identify patient with polytrauma who developed acute kidney injury.
Descriptive statistics were then obtained followed by hypothesis testing between variables with the chi squared
test. Logistic regression models were used to determine factors associated with acute kidney injury.
Results: More than half (56.4%) of the patients were between 26 and 40 years and 92.3% of the polytrauma
patients were males. Almost 2/5th (38.5%) of the polytrauma patients had acute kidney injury – half of these had
stage 1 AKI, 33.3% had stage 2 AKI and the remaining 16.7% had stage 3 AKI. On multivariate logistic regression,
it was found that patients who were older than 45 years (OR 8.53, CI 1.65–43.89, p = 0.01) and those patients
with Systemic Inflammatory Response Syndrome (SIRS) (OR 21.83, CI 1.66–286.2, p = 0.019) had higher risk of
acute kidney injury.
Conclusion: There is high prevalence of AKI among polytrauma patients. Elderly patients and those with SIRS
were seen to have higher likelihood of AKI
(AKI) is one of the most common causes and contributors to the high morbidity and mortality. Prevalence of
acute kidney injury in trauma patients is as reported to be as high as 40.3%. Early detection and management
leads to better outcomes. The prevalence of AKI among polytrauma patients remains unknown in our setting.
Methodology: A cross-sectional study involving all adults with polytrauma who presented at the emergency
department at Muhimbili Orthopedic Institute (MOI) was designed. A score of ≥18 on the New Injury Severity
Score (NISS) screening tool was used to identify polytrauma patients. The Kidney Disease Improving Global
Outcomes (KDIGO) criteria was used to identify patient with polytrauma who developed acute kidney injury.
Descriptive statistics were then obtained followed by hypothesis testing between variables with the chi squared
test. Logistic regression models were used to determine factors associated with acute kidney injury.
Results: More than half (56.4%) of the patients were between 26 and 40 years and 92.3% of the polytrauma
patients were males. Almost 2/5th (38.5%) of the polytrauma patients had acute kidney injury – half of these had
stage 1 AKI, 33.3% had stage 2 AKI and the remaining 16.7% had stage 3 AKI. On multivariate logistic regression,
it was found that patients who were older than 45 years (OR 8.53, CI 1.65–43.89, p = 0.01) and those patients
with Systemic Inflammatory Response Syndrome (SIRS) (OR 21.83, CI 1.66–286.2, p = 0.019) had higher risk of
acute kidney injury.
Conclusion: There is high prevalence of AKI among polytrauma patients. Elderly patients and those with SIRS
were seen to have higher likelihood of AKI
Creator
Mohamed S. Muhamedhussein , Mohamed Manji , Kitugi S. Nungu , Paschal Ruggajo , Karima Khalid
Source
www.elsevier.com/locate/afjem
Publisher
elsevier
Date
9 August 2020
Contributor
peri irawan
Format
pdf
Language
english
Type
text
Files
Citation
Mohamed S. Muhamedhussein , Mohamed Manji , Kitugi S. Nungu , Paschal Ruggajo , Karima Khalid, “Jurnal Internasional Afrika vol. 11 issue 1 2021
African Journal of Emergency Medicine
Prevalence and risk factors of acute kidney injury in polytrauma patients at Muhimbili Orthopedic Institute, Tanzania,” Repository Horizon University Indonesia, accessed December 23, 2024, https://repository.horizon.ac.id/items/show/2499.
African Journal of Emergency Medicine
Prevalence and risk factors of acute kidney injury in polytrauma patients at Muhimbili Orthopedic Institute, Tanzania,” Repository Horizon University Indonesia, accessed December 23, 2024, https://repository.horizon.ac.id/items/show/2499.