Jurnal Internasional Afrika vol. 11 issue 1 2021
African Journal of Emergency Medicine
Evaluation of the clinical outcome of captopril use for hypertensive urgency in Khartoum State’s emergency centres
Dublin Core
Title
Jurnal Internasional Afrika vol. 11 issue 1 2021
African Journal of Emergency Medicine
Evaluation of the clinical outcome of captopril use for hypertensive urgency in Khartoum State’s emergency centres
African Journal of Emergency Medicine
Evaluation of the clinical outcome of captopril use for hypertensive urgency in Khartoum State’s emergency centres
Subject
Captopril
Hypertensive urgency
Sudan
Blood pressure
Clinical outcome
Hypertensive urgency
Sudan
Blood pressure
Clinical outcome
Description
Background: Captopril is an important drug and is used to control hypertensive urgency world-wide. But there is
very little data available regarding the evaluation of its outcomes in hypertensive urgency among African patients.
This study aimed to evaluate the clinical outcomes of captopril use for hypertensive urgency at a selection
of Sudanese emergency centres.
Methods: This was a cross-sectional study, conducted between 15 to 30 November 2015. A total of 50 patients,
attending a selection of Khartoum State hospital emergency centres, with a clinical diagnosis of hypertensive
urgency were approached by investigators for the study. Dose regimen, prognosis, and reduction in systolic and
diastolic blood pressure were collected alongside a questionaire to patients regarding their care (compliance,
etc.). Data were analysed using the Chi-square Test to compare the mean differences for various results. Differences
were considered to be significant at P < 0.05.
Results: Around two-thirds (60%) of participants were female, and 28% were non-compliant with treatment. A
25mg dose of captopril was the most frequently used dose. Most of the patients (66%) did not have pre-existing
disease. The majority of patients showed an improved blood pressure: both systolic and diastolic blood pressures
were reduced by 16-25% and 5-15%, respectively.
Conclusion: The study concluded that the dose of 25 mg of captopril is effective in managing hypertensive urgency
and controlling the blood pressure. We also recommend that patients receiving captopril must be observed
in the emergency centre for further evaluation.
very little data available regarding the evaluation of its outcomes in hypertensive urgency among African patients.
This study aimed to evaluate the clinical outcomes of captopril use for hypertensive urgency at a selection
of Sudanese emergency centres.
Methods: This was a cross-sectional study, conducted between 15 to 30 November 2015. A total of 50 patients,
attending a selection of Khartoum State hospital emergency centres, with a clinical diagnosis of hypertensive
urgency were approached by investigators for the study. Dose regimen, prognosis, and reduction in systolic and
diastolic blood pressure were collected alongside a questionaire to patients regarding their care (compliance,
etc.). Data were analysed using the Chi-square Test to compare the mean differences for various results. Differences
were considered to be significant at P < 0.05.
Results: Around two-thirds (60%) of participants were female, and 28% were non-compliant with treatment. A
25mg dose of captopril was the most frequently used dose. Most of the patients (66%) did not have pre-existing
disease. The majority of patients showed an improved blood pressure: both systolic and diastolic blood pressures
were reduced by 16-25% and 5-15%, respectively.
Conclusion: The study concluded that the dose of 25 mg of captopril is effective in managing hypertensive urgency
and controlling the blood pressure. We also recommend that patients receiving captopril must be observed
in the emergency centre for further evaluation.
Creator
Amgad H.H. Obied , Aimun A.E. Ahmed
Source
www.elsevier.com/locate/afjem
Publisher
ELSEVIER
Date
11 October 2020
Contributor
PERI IRAWAN
Format
PDF
Language
ENGLISH
Type
TEXT
Files
Citation
Amgad H.H. Obied , Aimun A.E. Ahmed, “Jurnal Internasional Afrika vol. 11 issue 1 2021
African Journal of Emergency Medicine
Evaluation of the clinical outcome of captopril use for hypertensive urgency in Khartoum State’s emergency centres,” Repository Horizon University Indonesia, accessed March 15, 2025, https://repository.horizon.ac.id/items/show/2612.
African Journal of Emergency Medicine
Evaluation of the clinical outcome of captopril use for hypertensive urgency in Khartoum State’s emergency centres,” Repository Horizon University Indonesia, accessed March 15, 2025, https://repository.horizon.ac.id/items/show/2612.