JURNAL INTERNASIONAL KEBIDANAN 2020-2023 UNIVERSITAS KEDOKTERAN GUILAN VOLUME 30 ISSUE 2.
JOURNAL OF HOLISTIC NURSING OF MIDWIFERY.
The Relationship Between Psychosocial Status and Adherence to Treatment Regimen in Adolescents With Thalassemia

JURNAL INTERNASIONAL KEBIDANAN 2020-2023 UNIVERSITAS KEDOKTERAN GUILAN VOLUME 30 ISSUE 2.
JOURNAL OF HOLISTIC NURSING OF MIDWIFERY.
The Relationship Between Psychosocial Status and Adherence to Treatment Regimen in Adolescents With Thalassemia

Thalassemia, Psychosocialstatus, Treatment regimen, Adolescents

Introduction: Adherence to the treatment regimen is among the key principles in chronic
diseases, like thalassemia. The difficult treatment of these patients and the significant
biopsychosocial changes that occur during adolescence may lead to numerous psychosocial
changes. Such issuesmay affect their adherence to the treatment regimen.
Objective: The current study aimedto determine the relationship between psychosocial
status and adherence to the treatment regimen in adolescents with thalassemia referring to
hospitals in Rasht City, Iran.
Materials and Methods: Cross-sectional study was conducted on 66 adolescents with
thalassemia. The study samples included patients aged 11-21 years, referring to two
hospitals in Rasht City, Iran, in 2017. They were selected using the census methods. Data
collection tools included a demographic form and Pediatric Symptom Checklist-Youth
Report (PSC-Y). The compliance rate was measured by evaluating their adherence to
follow-up visits, average results of the last three ferritin tests, and iron chelator use. The
collected data were analyzed using descriptive statistics and the Chi-squared test, Fisher’s
exact test, and regression analysis.
Results: Fifty percent of patients reported psychosocial problems and most of them had good
adherence to follow-up visits (74.2%); however, their adherence to ferritin tests (47%) and
iron chelator use (45.5%) was poor. Regression analysis results suggested that the effect of
psychosocial status on adherence to follow-up visits (P<0.05, OR=0.8, 95% CI; 0.628-1), ferritin
test (P<0.05, OR=0.213, 95% CI; 0.044-1), and iron chelator use (P<0.001, OR=0.852, 95% CI;
0.772-0.94) was significant.
Conclusion: Adolescents with thalassemia fail to adhere to treatment regimen fully; therefore,
appropriate interventions are required to improve their psychosocial status.

Maryam Ghorbanpoor , Mahshid Mirzaie , Seyedeh Noshaz Mirhaghjou, Zahra Atrkar Roshan

April 2020, Volume 30, Number 2

PERI IRAWAN

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