Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 1 2020
Multifocal Recurrence of Medulloblastoma: A Long Follow-Up Case Study
Dublin Core
Title
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 1 2020
Multifocal Recurrence of Medulloblastoma: A Long Follow-Up Case Study
Multifocal Recurrence of Medulloblastoma: A Long Follow-Up Case Study
Subject
intra-axial mass, long follow-up, medulloblastoma, recurrence
Description
Medulloblastoma is the most common malignant brain tumor in pediatric patients. Leptomeningeal dissemination often occurs in the spinal canal and rarely into the supratentorial as an extra-axial lesion. This study followed an 8-year progression of
multifocal medulloblastoma recurrence as supratentorial metastasis that mimics an intra-axial mass of the temporal lobe. Pathologic examination of the temporal mass showed densely packed small round blue cells that are distributed in a ribboning pattern with areas of necrosis, rosette formation, and mitosis. Ki-67 immunohistochemical staining of the tumor showed a high proliferation index of 40% and revealed positive results for synaptophysin and negative results for glial fibrillary acidic protein and
β-catenin. A long follow-up is essential to diagnose the recurrence and elucidate the progression of medulloblastoma.
multifocal medulloblastoma recurrence as supratentorial metastasis that mimics an intra-axial mass of the temporal lobe. Pathologic examination of the temporal mass showed densely packed small round blue cells that are distributed in a ribboning pattern with areas of necrosis, rosette formation, and mitosis. Ki-67 immunohistochemical staining of the tumor showed a high proliferation index of 40% and revealed positive results for synaptophysin and negative results for glial fibrillary acidic protein and
β-catenin. A long follow-up is essential to diagnose the recurrence and elucidate the progression of medulloblastoma.
Creator
Benny Zulkarnaien, Edwin Suharlim, Eka Susanto, Soehartati Argadikoesoema Gondhowiardjo
Publisher
Fakultas Kedokteran Universitas Indonesia
Date
2020-03-26
Contributor
Sri Wahyuni
Rights
ISSN : 0853-1773
Format
PDF
Language
English
Type
Text
Coverage
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 1 2020
Files
Citation
Benny Zulkarnaien, Edwin Suharlim, Eka Susanto, Soehartati Argadikoesoema Gondhowiardjo, “Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 1 2020
Multifocal Recurrence of Medulloblastoma: A Long Follow-Up Case Study,” Repository Horizon University Indonesia, accessed October 13, 2024, https://repository.horizon.ac.id/items/show/813.
Multifocal Recurrence of Medulloblastoma: A Long Follow-Up Case Study,” Repository Horizon University Indonesia, accessed October 13, 2024, https://repository.horizon.ac.id/items/show/813.