LocalControl: An R Package for Comparative Safety and Effectiveness Research
Dublin Core
Title
LocalControl: An R Package for Comparative Safety and Effectiveness Research
Subject
: bias, R, survival, Kaplan-Meier, competing risks
Description
The LocalControl R package implements novel approaches to address biases and confounding when comparing treatments or exposures in observational studies of outcomes.
While designed and appropriate for use in comparative safety and effectiveness research
involving medicine and the life sciences, the package can be used in other situations involving outcomes with multiple confounders. LocalControl is an open-source tool for
researchers whose aim is to generate high quality evidence using observational data. The
package implements a family of methods for non-parametric bias correction when comparing treatments in observational studies, including survival analysis settings, where competing risks and/or censoring may be present. The approach extends to bias-corrected
personalized predictions of treatment outcome differences, and analysis of heterogeneity
of treatment effect-sizes across patient subgroups.
While designed and appropriate for use in comparative safety and effectiveness research
involving medicine and the life sciences, the package can be used in other situations involving outcomes with multiple confounders. LocalControl is an open-source tool for
researchers whose aim is to generate high quality evidence using observational data. The
package implements a family of methods for non-parametric bias correction when comparing treatments in observational studies, including survival analysis settings, where competing risks and/or censoring may be present. The approach extends to bias-corrected
personalized predictions of treatment outcome differences, and analysis of heterogeneity
of treatment effect-sizes across patient subgroups.
Creator
S. Stanley Young
Source
https://www.jstatsoft.org/article/view/v096i04
Publisher
CGStat, LLC
Date
November 2020
Contributor
Fajar bagus W
Format
PDF
Language
Inggris
Type
Text
Files
Collection
Citation
S. Stanley Young, “LocalControl: An R Package for Comparative Safety and Effectiveness Research,” Repository Horizon University Indonesia, accessed April 4, 2025, https://repository.horizon.ac.id/items/show/8170.