Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 3 2020
β-Endorphin Response to Aerobic and Anaerobic Exercises in Wistar Male Rats
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Title
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 3 2020
β-Endorphin Response to Aerobic and Anaerobic Exercises in Wistar Male Rats
β-Endorphin Response to Aerobic and Anaerobic Exercises in Wistar Male Rats
Subject
aerobic exercise, anaerobic exercise, β-endorphin
Description
BACKGROUND Physical exercise is strongly associated with the release of β-endorphin. It is assumed that the type and intensity of physical exercise contributes to the release of β-endorphin. This study aimed to compare levels of β-endorphin in brain tissue in response to aerobic and anaerobic physical exercise.
METHODS This study was an experimental laboratory study using 35 male Wistar rats divided into one control group and two physical exercise treatment groups: aerobic and anaerobic. Physical exercise was conducted on an animal treadmill running at a speed of 20 m/min for 30 min of aerobic exercise and 35 m/min with 1-min intervals every 5 min for 20 min for anaerobic exercises. Each aerobic and anaerobic exercise group was furtherly classified into three subgroups (1×/week, 3×/week, and 7×/week). β-endorphin levels were determined using enzyme-linked immunosorbent assay. The
data were analyzed using independent t-test and one-way analysis of variance.
RESULTS The highest mean of β-endorphin level was found in the weekly exercise (54.45 [1.41] pg/ml) of aerobic exercise group and daily exercise (70.50 [11.67] pg/ml) of anaerobic exercise group. Mean of β-endorphin level in control group was 33.34 (3.54) pg/ml. A significant increased of β-endorphin mean level (p<0.001) was found in
all aerobic and anaerobic exercise groups except the aerobic exercise 7×/week group (37.37 [6.30] pg/ml) compared to control.
CONCLUSIONS Both aerobic and anaerobic physical exercise conducted for 6 weeks could increase the level of β-endorphin in brain tissue.
METHODS This study was an experimental laboratory study using 35 male Wistar rats divided into one control group and two physical exercise treatment groups: aerobic and anaerobic. Physical exercise was conducted on an animal treadmill running at a speed of 20 m/min for 30 min of aerobic exercise and 35 m/min with 1-min intervals every 5 min for 20 min for anaerobic exercises. Each aerobic and anaerobic exercise group was furtherly classified into three subgroups (1×/week, 3×/week, and 7×/week). β-endorphin levels were determined using enzyme-linked immunosorbent assay. The
data were analyzed using independent t-test and one-way analysis of variance.
RESULTS The highest mean of β-endorphin level was found in the weekly exercise (54.45 [1.41] pg/ml) of aerobic exercise group and daily exercise (70.50 [11.67] pg/ml) of anaerobic exercise group. Mean of β-endorphin level in control group was 33.34 (3.54) pg/ml. A significant increased of β-endorphin mean level (p<0.001) was found in
all aerobic and anaerobic exercise groups except the aerobic exercise 7×/week group (37.37 [6.30] pg/ml) compared to control.
CONCLUSIONS Both aerobic and anaerobic physical exercise conducted for 6 weeks could increase the level of β-endorphin in brain tissue.
Creator
Rostika Flora, Mohammad Zulkarnain, Sukirno
Publisher
Fakultas Kedokteran Universitas Indonesia
Date
2020-10-05
Contributor
Sri Wahyuni
Rights
ISSN : 0853-1773
Format
PDF
Language
English
Type
Text
Coverage
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 3 2020
Files
Citation
Rostika Flora, Mohammad Zulkarnain, Sukirno
, “Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 3 2020
β-Endorphin Response to Aerobic and Anaerobic Exercises in Wistar Male Rats,” Repository Horizon University Indonesia, accessed September 20, 2024, https://repository.horizon.ac.id/items/show/890.
β-Endorphin Response to Aerobic and Anaerobic Exercises in Wistar Male Rats,” Repository Horizon University Indonesia, accessed September 20, 2024, https://repository.horizon.ac.id/items/show/890.