Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 3 2020
Bacterial Susceptibility Patterns to Cotrimoxazole in Urinary Tract Infections of Outpatients and Inpatients in Jakarta, Indonesia
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Title
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 3 2020
Bacterial Susceptibility Patterns to Cotrimoxazole in Urinary Tract Infections of Outpatients and Inpatients in Jakarta, Indonesia
Bacterial Susceptibility Patterns to Cotrimoxazole in Urinary Tract Infections of Outpatients and Inpatients in Jakarta, Indonesia
Subject
cotrimoxazole, inpatients, outpatients, urinary tract infections
Description
BACKGROUND Cotrimoxazole, which has been one of the drugs of choice for urinary tract infections (UTIs) since 1960, must be evaluated to determine whether it is still a relevant drug for this use. This study aimed to assess the susceptibility patterns to
cotrimoxazole of the bacteria that cause UTIs from urine samples of female outpatients (community-acquired [CA]-UTI) and inpatients (hospital-acquired [HA]-UTI) in Jakarta.
METHODS This study was conducted from December 2014 to December 2015. Susceptibility testing of bacteria causing UTIs was conducted on 27 of 311 female outpatient urine samples collected from six clinics in Jakarta, and secondary data
susceptibility testing was performed on 27 of 107 urine samples of inpatients from hospitals in Jakarta. These samples were examined in the Clinical Microbiology Laboratory, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital.
RESULTS Susceptibility to cotrimoxazole was reported in 83% of the bacteria causing UTIs in CA-UTI and 44% of the bacteria in HA-UTI patients. Klebsiella pneumoniae was the most common cause of CA-UTI, with all isolates susceptible to cotrimoxazole (100%). Conversely, Escherichia coli was the most common cause of HA-UTI but was only susceptible in some isolates (44%). Bacteria from CA-UTI patients were almost twice as
susceptible to cotrimoxazole compared with HA-UTI patients (p = 0.003).
CONCLUSIONS Based on the susceptibility patterns identified, cotrimoxazole can be
used as a treatment for CA-UTI but not for HA-UTI patients in Jakarta, Indonesia.
cotrimoxazole of the bacteria that cause UTIs from urine samples of female outpatients (community-acquired [CA]-UTI) and inpatients (hospital-acquired [HA]-UTI) in Jakarta.
METHODS This study was conducted from December 2014 to December 2015. Susceptibility testing of bacteria causing UTIs was conducted on 27 of 311 female outpatient urine samples collected from six clinics in Jakarta, and secondary data
susceptibility testing was performed on 27 of 107 urine samples of inpatients from hospitals in Jakarta. These samples were examined in the Clinical Microbiology Laboratory, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital.
RESULTS Susceptibility to cotrimoxazole was reported in 83% of the bacteria causing UTIs in CA-UTI and 44% of the bacteria in HA-UTI patients. Klebsiella pneumoniae was the most common cause of CA-UTI, with all isolates susceptible to cotrimoxazole (100%). Conversely, Escherichia coli was the most common cause of HA-UTI but was only susceptible in some isolates (44%). Bacteria from CA-UTI patients were almost twice as
susceptible to cotrimoxazole compared with HA-UTI patients (p = 0.003).
CONCLUSIONS Based on the susceptibility patterns identified, cotrimoxazole can be
used as a treatment for CA-UTI but not for HA-UTI patients in Jakarta, Indonesia.
Creator
Yeva Rosana, Dwiana Ocviyanti, Wafridha Akbar
Publisher
Fakultas Kedokteran Universitas Indonesia
Date
2020-10-05
Contributor
Sri Wahyuni
Rights
ISSN : 0853-1773
Format
PDF
Language
English
Type
Text
Coverage
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 3 2020
Files
Citation
Yeva Rosana, Dwiana Ocviyanti, Wafridha Akbar, “Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 3 2020
Bacterial Susceptibility Patterns to Cotrimoxazole in Urinary Tract Infections of Outpatients and Inpatients in Jakarta, Indonesia,” Repository Horizon University Indonesia, accessed March 12, 2025, https://repository.horizon.ac.id/items/show/895.
Bacterial Susceptibility Patterns to Cotrimoxazole in Urinary Tract Infections of Outpatients and Inpatients in Jakarta, Indonesia,” Repository Horizon University Indonesia, accessed March 12, 2025, https://repository.horizon.ac.id/items/show/895.