Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 4 2020
Retinal Vascular Caliber Changes after Laser Photocoagulation in Diabetic Retinopathy
Dublin Core
Title
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 4 2020
Retinal Vascular Caliber Changes after Laser Photocoagulation in Diabetic Retinopathy
Retinal Vascular Caliber Changes after Laser Photocoagulation in Diabetic Retinopathy
Subject
diabetic retinopathy, laser photocoagulation, retinal vascular caliber
Description
BACKGROUND Diabetic retinopathy causes vascular dilatation caused by hypoxia, whereas oxygen tension improvement leads to retinal vessels narrowing. Given that laser photocoagulation aims to increase the oxygen tension in the retina, we
hypothesized that the narrowing of vessel caliber after the treatment could be possibly demonstrated. This study aimed to assess the changes in the caliber of retinal vessels before and after laser photocoagulation in diabetic retinopathy.
METHODS This research was a prospective cohort study on the treatment of diabetic retinopathy by laser photocoagulation, and it was conducted at Universitas Hasanuddin Hospital, Makassar, Indonesia between November 2017–April 2018.
Retinal vascular caliber changes were analyzed before and 6–8 weeks after photocoagulation in 30 diabetic eyes. Central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE) were measured using the vessel assessment
and measurement platform software for images of the retina (VAMPIRE) manual annotation tool.
RESULTS A significant decrease of CRVE was observed after laser photocoagulation (p<0.001), but CRAE was not reduced significantly (p = 0.067). No difference was recorded between CRVE and CRAE post-laser photocoagulation (p = 0.14), implying a reduction in vein caliber toward normal in the treated eyes.
CONCLUSIONS Laser photocoagulation decreases the CRVE in diabetic retinopathy despite the absence of changes in the grade of diabetic retinopathy.
hypothesized that the narrowing of vessel caliber after the treatment could be possibly demonstrated. This study aimed to assess the changes in the caliber of retinal vessels before and after laser photocoagulation in diabetic retinopathy.
METHODS This research was a prospective cohort study on the treatment of diabetic retinopathy by laser photocoagulation, and it was conducted at Universitas Hasanuddin Hospital, Makassar, Indonesia between November 2017–April 2018.
Retinal vascular caliber changes were analyzed before and 6–8 weeks after photocoagulation in 30 diabetic eyes. Central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE) were measured using the vessel assessment
and measurement platform software for images of the retina (VAMPIRE) manual annotation tool.
RESULTS A significant decrease of CRVE was observed after laser photocoagulation (p<0.001), but CRAE was not reduced significantly (p = 0.067). No difference was recorded between CRVE and CRAE post-laser photocoagulation (p = 0.14), implying a reduction in vein caliber toward normal in the treated eyes.
CONCLUSIONS Laser photocoagulation decreases the CRVE in diabetic retinopathy despite the absence of changes in the grade of diabetic retinopathy.
Creator
Habibah Setyawati Muhiddin, Idayani Panggalo, Andi Muhammad Ichsan, Budu, Emanuele Trucco, John Ellis
Publisher
Fakultas Kedokteran Universitas Indonesia
Date
2021-01-01
Contributor
Sri Wahyuni
Rights
ISSN : 0853-1773
Format
PDF
Language
English
Type
Text
Coverage
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 4 2020
Files
Citation
Habibah Setyawati Muhiddin, Idayani Panggalo, Andi Muhammad Ichsan, Budu, Emanuele Trucco, John Ellis , “Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 4 2020
Retinal Vascular Caliber Changes after Laser Photocoagulation in Diabetic Retinopathy,” Repository Horizon University Indonesia, accessed November 21, 2024, https://repository.horizon.ac.id/items/show/906.
Retinal Vascular Caliber Changes after Laser Photocoagulation in Diabetic Retinopathy,” Repository Horizon University Indonesia, accessed November 21, 2024, https://repository.horizon.ac.id/items/show/906.