Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 4 2020
Predictors of Smear Non-Conversion among New-Treatment Pulmonary Tuberculosis: A Single Center Case-Control Study in Indonesia
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Title
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 4 2020
Predictors of Smear Non-Conversion among New-Treatment Pulmonary Tuberculosis: A Single Center Case-Control Study in Indonesia
Predictors of Smear Non-Conversion among New-Treatment Pulmonary Tuberculosis: A Single Center Case-Control Study in Indonesia
Subject
microbiological techniques, Mycobacterium, pulmonary tuberculosis
Description
BACKGROUND Previous studies concluded predictors of smear non-conversion pulmonary tuberculosis (TB) globally as well as in Indonesia. However, there is a limited data in hospital setting. This study aimed to explore predictors of smear non-conversion pulmonary TB in hospital setting.
METHODS A case-control study was conducted to explore predictors of smear nonconversion among new-treatment pulmonary TB in Dr. Kariadi General Hospital from 2017 to 2019. Number of cases and controls have been determined consecutively. Data were collected from secondary data accessed in medical records and directly from subjects. Non-conversion status in the case group was defined as a persistent sputum smear-positive after 2 months of intensive phase of treatment. The subjects’ characteristics i.e., age, sex, body mass index, education level, occupational status, and predictors of smear non-conversion, i.e., patient’s compliance, smoking status, alcohol consumption, presence of drugs side effects, health care access, first acidfast bacilli (AFB) smear grading, diabetes mellitus (DM), housing condition, housing density, and household income were observed. Chi-square test and binary logistic regression were used.
RESULTS 35 subjects were determined in the case group while 76 subjects were the control group and involved in the final analysis. Age, sex, first AFB smear grading, smoking status, housing condition, housing density, and DM were involved in the
model of logistic regression. DM (OR = 3.4; 95% CI = 1.19–10.00) and first AFB smear grading (OR = 11.2; 95% CI = 3.86–33.00) were concluded as the predictors of smear non-conversion.
CONCLUSIONS DM and first AFB smear grading were the predictors of smear nonconversion among new-treatment pulmonary TB subjects.
METHODS A case-control study was conducted to explore predictors of smear nonconversion among new-treatment pulmonary TB in Dr. Kariadi General Hospital from 2017 to 2019. Number of cases and controls have been determined consecutively. Data were collected from secondary data accessed in medical records and directly from subjects. Non-conversion status in the case group was defined as a persistent sputum smear-positive after 2 months of intensive phase of treatment. The subjects’ characteristics i.e., age, sex, body mass index, education level, occupational status, and predictors of smear non-conversion, i.e., patient’s compliance, smoking status, alcohol consumption, presence of drugs side effects, health care access, first acidfast bacilli (AFB) smear grading, diabetes mellitus (DM), housing condition, housing density, and household income were observed. Chi-square test and binary logistic regression were used.
RESULTS 35 subjects were determined in the case group while 76 subjects were the control group and involved in the final analysis. Age, sex, first AFB smear grading, smoking status, housing condition, housing density, and DM were involved in the
model of logistic regression. DM (OR = 3.4; 95% CI = 1.19–10.00) and first AFB smear grading (OR = 11.2; 95% CI = 3.86–33.00) were concluded as the predictors of smear non-conversion.
CONCLUSIONS DM and first AFB smear grading were the predictors of smear nonconversion among new-treatment pulmonary TB subjects.
Creator
Arulita Ika Fibriana, Muhamad Zakki Saefurrohim, Akhriyah Atsna Setiana, Mahalul Azam, Avissena Dutha Pratama
Publisher
Fakultas Kedokteran Universitas Indonesia
Date
2021-01-01
Contributor
Sri Wahyuni
Rights
ISSN : 0853-1773
Format
PDF
Language
English
Type
Text
Coverage
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 4 2020
Files
Citation
Arulita Ika Fibriana, Muhamad Zakki Saefurrohim, Akhriyah Atsna Setiana, Mahalul Azam, Avissena Dutha Pratama, “Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 29 No. 4 2020
Predictors of Smear Non-Conversion among New-Treatment Pulmonary Tuberculosis: A Single Center Case-Control Study in Indonesia,” Repository Horizon University Indonesia, accessed November 22, 2024, https://repository.horizon.ac.id/items/show/922.
Predictors of Smear Non-Conversion among New-Treatment Pulmonary Tuberculosis: A Single Center Case-Control Study in Indonesia,” Repository Horizon University Indonesia, accessed November 22, 2024, https://repository.horizon.ac.id/items/show/922.