Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 1 2021
A Randomized Controlled Trial of Infraorbital Block using Ketamine 1% for Intra- and Postoperative Analgesia in Children for Ambulatory Cleft Lip Correction
Dublin Core
Title
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 1 2021
A Randomized Controlled Trial of Infraorbital Block using Ketamine 1% for Intra- and Postoperative Analgesia in Children for Ambulatory Cleft Lip Correction
A Randomized Controlled Trial of Infraorbital Block using Ketamine 1% for Intra- and Postoperative Analgesia in Children for Ambulatory Cleft Lip Correction
Subject
cleft lip, ketamine, postoperative pain
Description
BACKGROUND In Indonesia, cleft lip correction surgery is often done as a social program in remote areas with limited resources. This study aimed to assess the effectiveness of ketamine, a cheaper and more accessible alternative, as a local analgesia in infraorbital block and to determine the possibility of ketamine as an alternative local analgesic drug for intraoperative and postoperative periods.
METHODS This was a randomized controlled trial in children aged 2 months to 5 years who underwent cleft lip correction surgery at Cipto Mangunkusumo Hospital in 2016. Subjects were randomly divided into two groups: ketamine and bupivacaine. Standard general anesthesia with endotracheal intubation was performed in each
group. Bilateral intraoral infraorbital block was performed using ketamine 1% 0.5 ml or bupivacaine 0.25% 0.5 ml. Postoperative evaluation includes pain scores based on the face, leg, activity, cry, and consolability (FLACC) scale and analgesic duration.
RESULTS A total of 36 subjects were enrolled in this study, with 18 in each group. Both groups received the same total amount of fentanyl addition intraoperatively (p = 1). The postoperative FLACC pain scale scores between the two groups were not different, with p>0.05 in every measurement. The mean duration of postoperative analgesia in the ketamine group was longer than the bupivacaine group (15–13.49 hours, p = 0.031).
CONCLUSIONS Infraorbital block with 1% ketamine 0.5 mg/kg was similarly effective for
intraoperative and postoperative analgesia but had a longer duration than that with 0.25% bupivacaine 0.5 ml in ambulatory cleft lip correction.
METHODS This was a randomized controlled trial in children aged 2 months to 5 years who underwent cleft lip correction surgery at Cipto Mangunkusumo Hospital in 2016. Subjects were randomly divided into two groups: ketamine and bupivacaine. Standard general anesthesia with endotracheal intubation was performed in each
group. Bilateral intraoral infraorbital block was performed using ketamine 1% 0.5 ml or bupivacaine 0.25% 0.5 ml. Postoperative evaluation includes pain scores based on the face, leg, activity, cry, and consolability (FLACC) scale and analgesic duration.
RESULTS A total of 36 subjects were enrolled in this study, with 18 in each group. Both groups received the same total amount of fentanyl addition intraoperatively (p = 1). The postoperative FLACC pain scale scores between the two groups were not different, with p>0.05 in every measurement. The mean duration of postoperative analgesia in the ketamine group was longer than the bupivacaine group (15–13.49 hours, p = 0.031).
CONCLUSIONS Infraorbital block with 1% ketamine 0.5 mg/kg was similarly effective for
intraoperative and postoperative analgesia but had a longer duration than that with 0.25% bupivacaine 0.5 ml in ambulatory cleft lip correction.
Creator
Andi Ade Wijaya Ramlan, Apriliana Ratnaningrum, Arif Hari Martono Marsaban
Publisher
Fakultas Kedokteran Universitas Indonesia
Date
2021-03-31
Contributor
Sri Wahyuni
Rights
ISSN : 0853-1773
Format
PDF
Language
English
Type
Text
Coverage
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 1 2021
Files
Citation
Andi Ade Wijaya Ramlan, Apriliana Ratnaningrum, Arif Hari Martono Marsaban, “Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 1 2021
A Randomized Controlled Trial of Infraorbital Block using Ketamine 1% for Intra- and Postoperative Analgesia in Children for Ambulatory Cleft Lip Correction,” Repository Horizon University Indonesia, accessed November 21, 2024, https://repository.horizon.ac.id/items/show/961.
A Randomized Controlled Trial of Infraorbital Block using Ketamine 1% for Intra- and Postoperative Analgesia in Children for Ambulatory Cleft Lip Correction,” Repository Horizon University Indonesia, accessed November 21, 2024, https://repository.horizon.ac.id/items/show/961.