Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 2 2021
A Case Report of Acute Marchiafava-Bignami Disease: A Rare Clinical Entity in Chronic Alcoholism
Dublin Core
Title
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 2 2021
A Case Report of Acute Marchiafava-Bignami Disease: A Rare Clinical Entity in Chronic Alcoholism
A Case Report of Acute Marchiafava-Bignami Disease: A Rare Clinical Entity in Chronic Alcoholism
Subject
alcoholics, case reports, corpus callosum, magnetic resonance imaging, Marchiafava-Bignami disease, Wernicke encephalopathy
Description
Marchiafava‑Bignami disease (MBD) is a rare neurological disease often associated with a chronic consumption of alcohol and malnutrition, which is characterized by a demyelination and necrosis of the corpus callosum. We present a case of a 21-yearold male with chronic alcoholism who presented with an acute altered sensorium and seizure, which were initially treated as meningoencephalitis. His persistent poor Glasgow coma scale score and ideomotor recovery with encephalitic changes on his electroencephalogram prompted urgent magnetic resonance imaging (MRI) of his brain, which revealed extensive symmetrical hyperintensities in the corpus callosum. The diagnosis of MBD was made because of the typical MRI findings and after the exclusion of other possible diagnosis. The patient was promptly treated with a parenteral thiamine and showed a good recovery at 3 months follow-up. This case
highlights the importance of diagnosing and recognizing MBD in a patient with chronic
alcoholism as prompt treatment could prevent irreversible damage, which could carry high morbidity.
highlights the importance of diagnosing and recognizing MBD in a patient with chronic
alcoholism as prompt treatment could prevent irreversible damage, which could carry high morbidity.
Creator
Mohd Arif Abdul Malik Khiew, Abdul Hanif Khan Yusof Khan, Wei Chao Loh, Liyana Najwa Inche Mat, Peck Kee Chia, Wan Aliaa Wan Sulaiman, Fan Kee Hoo, Hamidon Basri
Publisher
Fakultas Kedokteran Universitas Indonesia
Date
2021-06-30
Contributor
Sri Wahyuni
Rights
ISSN : 0853-1773
Format
PDF
Language
English
Type
Text
Coverage
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 2 2021
Files
Citation
Mohd Arif Abdul Malik Khiew, Abdul Hanif Khan Yusof Khan, Wei Chao Loh, Liyana Najwa Inche Mat, Peck Kee Chia, Wan Aliaa Wan Sulaiman, Fan Kee Hoo, Hamidon Basri , “Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 2 2021
A Case Report of Acute Marchiafava-Bignami Disease: A Rare Clinical Entity in Chronic Alcoholism,” Repository Horizon University Indonesia, accessed September 20, 2024, https://repository.horizon.ac.id/items/show/992.
A Case Report of Acute Marchiafava-Bignami Disease: A Rare Clinical Entity in Chronic Alcoholism,” Repository Horizon University Indonesia, accessed September 20, 2024, https://repository.horizon.ac.id/items/show/992.