The effectiveness of wound caring
technique with polyhexamethylene
biguanide and dialkyl carbamoyl
chloride to healing process duration of
diabetic foot ulcer patient

The effectiveness of wound caring
technique with polyhexamethylene
biguanide and dialkyl carbamoyl
chloride to healing process duration of
diabetic foot ulcer patient

diabetic foot ulcer; wound healing

Background: Antimicrobial dressing on moist-based wound care is a
successful wound care technique, especially for diabetes mellitus wounds.
The moisture on wound can be made by closed wound care to reach a
standard moisture in various wounds. The antimicrobial dressing type that
can increase the wound healing is Polyhexamethylene biguanide (PHMB)
and Dialkyl carbamoyl chloride (DACC). Polyhexamethylene biguanide can
accelerate the tissue granulation and reduce the risk of infection. Dialkyl
carbamoyl chloride is a part of moist wound healing with strong hydrophobic
threat so the bacteria will be lifted and accelerate the wound healing process.
Purpose: The aim of this research is to analyze the effect of healing technique
using Polyhexamethylene biguanide and Dialkyl carbamoyl chloride wound
healing process on diabetic foot ulcer patients.
Methods: This research was quasi-experimental with 129 respondents.
The instruments were Bates Jensen’s observation sheet and data were
processed by double linear regression.
Results: It was obtained an average difference between the duration of the
wound healing process between PHMB and DACC therapy with a p-value
of 0.0005.
Conclusions: The use of this type of DACC dressing is more effective
against the duration of the healing process of diabetic foot ulcers because of
the time needed for DACC to work on killing bacteria in-vitro in 30 minutes
compared to other dressing.

Armi Armi1* , Dewi Fitriani2 , Mila Sartika1 , Yana Setiawan1

http://jkp.fkep.unpad.ac.id/index.
php/jkp

April 27, 2023

PERI IRAWAN

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