Medical Journal of Indonesia Vol. 31 No. 3 2022 FKUI
A Randomized Control Trial of Platelet-Rich Plasma in Supporting the Recovery of Postpartum Levator Ani Muscle Trauma

Medical Journal of Indonesia Vol. 31 No. 3 2022 FKUI
A Randomized Control Trial of Platelet-Rich Plasma in Supporting the Recovery of Postpartum Levator Ani Muscle Trauma

KEYWORDS obstetric labor complication, parturition, pelvic floor disorder, platelet-rich
plasma, randomized controlled trial

Pelvic floor dysfunction (PFD) is a pathological
condition of pelvic floor muscle weakness, most
commonly caused by a vaginal birth process.1
More
than 46% of women with a history of vaginal birth have
PFD. PFD occurs due to multiple structure disruptions,
including levator ani muscles (LAMs), anal sphincter,
and perineum, and causes symptoms of urinary and

fecal incontinence.2 LAM defect is classified into macro-
and microtrauma. Macrotrauma, also called avulsion,

is a complete detachment of LAM from the inferior

pubic ramus. Meanwhile, microtrauma, also called
ballooning, is an over distention of the LAM. Both are
two independent risk factors for PFD and lead to pelvic
organ prolapse (POP) and stress urinary incontinence
(SUI).3 The prevalence of SUI 3 months after delivery
in Indonesia was estimated at 20.1%, while primiparous
women with vaginal delivery had a 2.1 times higher risk
of developing SUI.4

Unfortunately, postpartum SUI
treatment is still limited to lifestyle and pelvic floor
rehabilitation.5

Fernandi Moegni, Andhika Rachman, Ermita Ibrahim Ilyas, Alida
Harahap, Trika Irianta, Ferry Hidayat, Dwiana Ocviyanti, Budi Iman Santoso

https://doi.org/10.13181/mji.oa.226115

December 02, 2022

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