Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI
Evaluation of Anal Cytology and Human Papillomavirus Infection in High-Risk Women: A Cross-Sectional Study
Dublin Core
Title
Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI
Evaluation of Anal Cytology and Human Papillomavirus Infection in High-Risk Women: A Cross-Sectional Study
Evaluation of Anal Cytology and Human Papillomavirus Infection in High-Risk Women: A Cross-Sectional Study
Subject
anal neoplasms, cytology, human papillomavirus, Papanicolaou test,
uterine cervical neoplasms
uterine cervical neoplasms
Description
BACKGROUND Anal cancer incidence has been on the rise over the past few decades.
This study aimed to assess anal Papanicolaou (Pap) smear changes in women with high
risk for dysplasia and human papillomavirus (HPV) infection.
METHODS This cross-sectional study was conducted in 121 patients referred to the
Gynecology Oncology Clinic of Imam Hossein Medical Center between 2020 and 2021 in
Tehran, Iran, who had cervical and vulvar dysplasia, cervical HPV infection, and abnormal
cervical cytology results and were over 21 years old. Data analysis was performed using
SPSS software version 21 (IBM Corp., USA) at a significance level of 0.05.
RESULTS 121 women, with a mean age of 39.69 years, were included in this study.
Overall, 23.1% of women had positive anal HPV results, and 35.5% were over 40 years
old. Younger age was associated with an increased risk of anal HPV (p = 0.045). 33.9%
of women were single and had a higher risk of anal HPV. Multiple sexual partnerships
and anal sex were the significant risk factors for anal cancer (p<0.001). Women with
positive anal HPV results had significantly more genital warts (p<0.001). No significant
difference was observed in smoking, educational level, and cervical Pap smear results
between women with negative and positive rectal HPV results.
CONCLUSIONS Younger age at diagnosis, being single, multiple sexual partnerships,
anal sex, and genital warts were associated with anal HPV infection in women.
Abnormal anal cytology was only associated with being single and having multiple
sexual partners.
This study aimed to assess anal Papanicolaou (Pap) smear changes in women with high
risk for dysplasia and human papillomavirus (HPV) infection.
METHODS This cross-sectional study was conducted in 121 patients referred to the
Gynecology Oncology Clinic of Imam Hossein Medical Center between 2020 and 2021 in
Tehran, Iran, who had cervical and vulvar dysplasia, cervical HPV infection, and abnormal
cervical cytology results and were over 21 years old. Data analysis was performed using
SPSS software version 21 (IBM Corp., USA) at a significance level of 0.05.
RESULTS 121 women, with a mean age of 39.69 years, were included in this study.
Overall, 23.1% of women had positive anal HPV results, and 35.5% were over 40 years
old. Younger age was associated with an increased risk of anal HPV (p = 0.045). 33.9%
of women were single and had a higher risk of anal HPV. Multiple sexual partnerships
and anal sex were the significant risk factors for anal cancer (p<0.001). Women with
positive anal HPV results had significantly more genital warts (p<0.001). No significant
difference was observed in smoking, educational level, and cervical Pap smear results
between women with negative and positive rectal HPV results.
CONCLUSIONS Younger age at diagnosis, being single, multiple sexual partnerships,
anal sex, and genital warts were associated with anal HPV infection in women.
Abnormal anal cytology was only associated with being single and having multiple
sexual partners.
Creator
Tahereh Ashrafganjoei, Maryam Sadat Hosseini, Zanbagh Pirastehfar, Farah Farzaneh, Maliheh Arab, Noushin Afshar Moghaddam, Abdolreza Javadi, Ali Yaghobi Joybari
Source
https://doi.org/10.13181/mji.oa.236375
Date
March 10, 2023
Contributor
peri irawan
Format
pdf
Language
english
Type
text
Files
Citation
Tahereh Ashrafganjoei, Maryam Sadat Hosseini, Zanbagh Pirastehfar, Farah Farzaneh, Maliheh Arab, Noushin Afshar Moghaddam, Abdolreza Javadi, Ali Yaghobi Joybari, “Medical Journal of Indonesia Vol. 31 No. 4 2022 FKUI
Evaluation of Anal Cytology and Human Papillomavirus Infection in High-Risk Women: A Cross-Sectional Study,” Repository Horizon University Indonesia, accessed February 6, 2025, https://repository.horizon.ac.id/items/show/1089.
Evaluation of Anal Cytology and Human Papillomavirus Infection in High-Risk Women: A Cross-Sectional Study,” Repository Horizon University Indonesia, accessed February 6, 2025, https://repository.horizon.ac.id/items/show/1089.