The Potential of Betel Leaf (Piper betle L.) Against Bacteria to Cure Mastitis: A Systematic Review
Dublin Core
Title
The Potential of Betel Leaf (Piper betle L.) Against Bacteria to Cure Mastitis: A Systematic Review
Subject
Betel leaf, Piper
betle L.,
Staphylococcus
aureus, mastitis
betle L.,
Staphylococcus
aureus, mastitis
Description
Introduction: Mastitis is a problem in breastfeeding that causes nutritional
deficiencies in the baby. Staphylococcus aureus is one of the bacteria that
cause mastitis. Betel leaf (Piper betle L.) has been used in several health
problems and has antimicrobial activity. This study aims to explore the
potential of betel leaf (Piper betle L.) against bacteria to cure mastitis.
Methods: A systematic review was carried out according to the PRISMA
guidelines. Searches were conducted in three databases namely PubMed,
Google Scholar, and ScienceDirect. The search uses keywords according to
the Mesh term, namely 'betel leaf (Piper betle L.)', ‘bacteria’, and 'Mastitis'.
198 articles were found in a database search. 15 studies were analyzed.
Results: All studies found that both types of piper betle, both green and red,
showed positive effects in the treatment of mastitis. Processing techniques,
storage, and certain concentrations such as boiling temperature affect the
optimum inhibition zone of bacteria. The addition of certain formulas also
increases the antimicrobial activity.
Conclusion: The use of antibiotics and betel leaf extract can be used
simultaneously to treat mastitis. Betel leaf (Piper betle L.), has a positive
effect on the management of mastitis, but processing techniques,
concentrations, and adjuvants need to be studied further.
deficiencies in the baby. Staphylococcus aureus is one of the bacteria that
cause mastitis. Betel leaf (Piper betle L.) has been used in several health
problems and has antimicrobial activity. This study aims to explore the
potential of betel leaf (Piper betle L.) against bacteria to cure mastitis.
Methods: A systematic review was carried out according to the PRISMA
guidelines. Searches were conducted in three databases namely PubMed,
Google Scholar, and ScienceDirect. The search uses keywords according to
the Mesh term, namely 'betel leaf (Piper betle L.)', ‘bacteria’, and 'Mastitis'.
198 articles were found in a database search. 15 studies were analyzed.
Results: All studies found that both types of piper betle, both green and red,
showed positive effects in the treatment of mastitis. Processing techniques,
storage, and certain concentrations such as boiling temperature affect the
optimum inhibition zone of bacteria. The addition of certain formulas also
increases the antimicrobial activity.
Conclusion: The use of antibiotics and betel leaf extract can be used
simultaneously to treat mastitis. Betel leaf (Piper betle L.), has a positive
effect on the management of mastitis, but processing techniques,
concentrations, and adjuvants need to be studied further.
Creator
Rahma Winahyu Jannata1,2*
, Prihantono3, & Irfan Idris4
, Prihantono3, & Irfan Idris4
Source
https://doi.org/10.37363/bnr.2023.43269
Date
28 July 2023
Contributor
peri irawan
Format
pdf
Language
english
Type
text
Files
Collection
Citation
Rahma Winahyu Jannata1,2*
, Prihantono3, & Irfan Idris4, “The Potential of Betel Leaf (Piper betle L.) Against Bacteria to Cure Mastitis: A Systematic Review,” Repository Horizon University Indonesia, accessed April 25, 2026, https://repository.horizon.ac.id/items/show/11562.