Monkeypox epidemiology, clinical presentation, and transmission: a systematic review
Dublin Core
Title
Monkeypox epidemiology, clinical presentation, and transmission: a systematic review
Subject
Complications, Epidemiology, Monkeypox, Monkeypox virus, Transmission
Description
Background The new zoonotic viral infection, monkeypox, is a global health issue. Our study aimed at studying the
epidemiology, clinical presentation, complications, case fatality rate, and transmission among the present cases of
monkeypox infection.
Methods Articles were searched in PubMed, Google Scholar, and Science Direct databases using the keywords
“Monkeypox” [MeSH] or “Monkeypox virus” (MeSH). Narrative reviews, conference abstracts, commentaries, and articles
in languages other than English were excluded.
Results From three databases, 1442 studies were identified. Seven hundred ten articles were excluded because
they included data before 2022, leaving 732 items for screening. After filtering 320 data due to data duplication, 412
remained. Due to the inclusion of systematic reviews, meta-analyses, reviews, comments, and articles in languages
other than English, 257 were excluded. Eligibility based on full-text review was applied to the remaining 155, exclud-
ing 129. So, the study covered a total of remaining 26 articles. We studied 2352 confirmed cases from published
literature, accounting for approximately 4% of infected cases worldwide. Around 81.71% of patients have a bisexual
or men having sex with men (MSM) preference. Approximately 30.18% of confirmed cases were HIV positive. Male sex
was also identified as a risk factor in our review.
Conclusion Monkeypox human-to-human and human-to-animal transmission are rising. Thus, it is essential to do
research on the prevention, clinicodemographic trends, and treatment of monkeypox. Understanding this will enable
us to treat monkeypox patients with a targeted and focused approach.
epidemiology, clinical presentation, complications, case fatality rate, and transmission among the present cases of
monkeypox infection.
Methods Articles were searched in PubMed, Google Scholar, and Science Direct databases using the keywords
“Monkeypox” [MeSH] or “Monkeypox virus” (MeSH). Narrative reviews, conference abstracts, commentaries, and articles
in languages other than English were excluded.
Results From three databases, 1442 studies were identified. Seven hundred ten articles were excluded because
they included data before 2022, leaving 732 items for screening. After filtering 320 data due to data duplication, 412
remained. Due to the inclusion of systematic reviews, meta-analyses, reviews, comments, and articles in languages
other than English, 257 were excluded. Eligibility based on full-text review was applied to the remaining 155, exclud-
ing 129. So, the study covered a total of remaining 26 articles. We studied 2352 confirmed cases from published
literature, accounting for approximately 4% of infected cases worldwide. Around 81.71% of patients have a bisexual
or men having sex with men (MSM) preference. Approximately 30.18% of confirmed cases were HIV positive. Male sex
was also identified as a risk factor in our review.
Conclusion Monkeypox human-to-human and human-to-animal transmission are rising. Thus, it is essential to do
research on the prevention, clinicodemographic trends, and treatment of monkeypox. Understanding this will enable
us to treat monkeypox patients with a targeted and focused approach.
Creator
Ashima Sharma1
, Hari Prasad2
, Nidhi Kaeley2*, Aparna Bondalapati1
, Lokesh Edara3 and Y. Ajay Kumar1
, Hari Prasad2
, Nidhi Kaeley2*, Aparna Bondalapati1
, Lokesh Edara3 and Y. Ajay Kumar1
Source
https://doi.org/10.1186/s12245-023-00491-3
Date
2023
Contributor
peri irawan
Format
pdf
Language
english
Type
text
Files
Collection
Citation
Ashima Sharma1
, Hari Prasad2
, Nidhi Kaeley2*, Aparna Bondalapati1
, Lokesh Edara3 and Y. Ajay Kumar1, “Monkeypox epidemiology, clinical presentation, and transmission: a systematic review,” Repository Horizon University Indonesia, accessed April 26, 2026, https://repository.horizon.ac.id/items/show/12120.