An AI-based multiphase framework for improving the mechanical ventilation availability in emergency departments during respiratory disease seasons: a case study

Dublin Core

Title

An AI-based multiphase framework for improving the mechanical ventilation availability in emergency departments during respiratory disease seasons: a case study

Subject

Artificial Intelligence (AI), Random Forest (RF), Discrete-Event-Simulation (DES), Emergency Department
(ED), Mechanical ventilation, Healthcare

Description

Background Shortages of mechanical ventilation have become a constant problem in Emergency Departments
(EDs), thereby affecting the timely deployment of medical interventions that counteract the severe health
complications experienced during respiratory disease seasons. It is then necessary to count on agile and robust
methodological approaches predicting the expected demand loads to EDs while supporting the timely allocation of
ventilators. In this paper, we propose an integration of Artificial Intelligence (AI) and Discrete-event Simulation (DES)
to design effective interventions ensuring the high availability of ventilators for patients needing these devices.

Methods First, we applied Random Forest (RF) to estimate the mechanical ventilation probability of respiratory-
affected patients entering the emergency wards. Second, we introduced the RF predictions into a DES model

to diagnose the response of EDs in terms of mechanical ventilator availability. Lately, we pretested two different
interventions suggested by decision-makers to address the scarcity of this resource. A case study in a European
hospital group was used to validate the proposed methodology.
Results The number of patients in the training cohort was 734, while the test group comprised 315. The sensitivity
of the AI model was 93.08% (95% confidence interval, [88.46 −96.26%]), whilst the specificity was 85.45% [77.45
−91.45%]. On the other hand, the positive and negative predictive values were 91.62% (86.75 −95.13%) and 87.85%
(80.12 −93.36%). Also, the Receiver Operator Characteristic (ROC) curve plot was 95.00% (89.25 −100%). Finally,
the median waiting time for mechanical ventilation was decreased by 17.48% after implementing a new resource
capacity strategy.
Conclusions Combining AI and DES helps healthcare decision-makers to elucidate interventions shortening the
waiting times for mechanical ventilators in EDs during respiratory disease epidemics and pandemics.
Keywords Artificial Intelligence (AI), Random Forest (RF), Discrete-Event-Simulation (DES), Emergency Department
(ED), Mechanical ventilation, Healthcare

Creator

Miguel Ortiz-Barrios1,2*, Antonella Petrillo3

, Sebastián Arias-Fonseca2

, Sally McClean4

, Fabio de Felice3

, Chris Nugent4

and Sheyla-Ariany Uribe-López5

Source

https://doi.org/10.1186/s12245-024-00626-0

Date

2024

Contributor

Peri Irawan

Format

pdf

Language

english

Type

text

Files

Citation

Miguel Ortiz-Barrios1,2*, Antonella Petrillo3 , Sebastián Arias-Fonseca2 , Sally McClean4 , Fabio de Felice3 , Chris Nugent4 and Sheyla-Ariany Uribe-López5, “An AI-based multiphase framework for improving the mechanical ventilation availability in emergency departments during respiratory disease seasons: a case study,” Repository Horizon University Indonesia, accessed April 11, 2026, https://repository.horizon.ac.id/items/show/12333.