Case report: a case of AL amyloidosis with spontaneous giant retroperitoneal hematoma
Dublin Core
Title
Case report: a case of AL amyloidosis with spontaneous giant retroperitoneal hematoma
Subject
Immunoglobulin light chain amyloidosis (AL), Factor X deficiency, Case report
Description
Abstract
Background Systemic amyloidosis is a kind of clinical syndrome in which amyloid is deposited between the cells
of various organs in the body, resulting in gradual failure of the function of the affected organs. Depending on the site
of amyloid deposition, it may show various clinical symptoms of multiple system involvement.
Patient concerns A 44-years-old female with spontaneous giant retroperitoneal hematoma was admitted
to the emergency department of Peking Union Medical College Hospital in Mar 2023.
Diagnoses She was found with a extremely X-factor deficiency and diagnosed with AL amyloidosis according
to pathological findings finally.
Interventions and outcomes She received a variety of treatments to improve her coagulation function and under-
went chemotherapy for AL in the hematology department which improved her coagulation function and was dis-
charged to her local hospital for follow-up treatment.
Conclusion This case provides a new reference for emergency doctors in the diagnosis and treatment of acute
severe hemorrhagic diseases.
Keywords Immunoglobulin light chain amyloidosis (AL), Factor X deficiency, Case report
Background Systemic amyloidosis is a kind of clinical syndrome in which amyloid is deposited between the cells
of various organs in the body, resulting in gradual failure of the function of the affected organs. Depending on the site
of amyloid deposition, it may show various clinical symptoms of multiple system involvement.
Patient concerns A 44-years-old female with spontaneous giant retroperitoneal hematoma was admitted
to the emergency department of Peking Union Medical College Hospital in Mar 2023.
Diagnoses She was found with a extremely X-factor deficiency and diagnosed with AL amyloidosis according
to pathological findings finally.
Interventions and outcomes She received a variety of treatments to improve her coagulation function and under-
went chemotherapy for AL in the hematology department which improved her coagulation function and was dis-
charged to her local hospital for follow-up treatment.
Conclusion This case provides a new reference for emergency doctors in the diagnosis and treatment of acute
severe hemorrhagic diseases.
Keywords Immunoglobulin light chain amyloidosis (AL), Factor X deficiency, Case report
Creator
Yaqi Sheng1 and Huadong Zhu1*
Source
https://doi.org/10.1186/s12245-024-00801-3
Date
2024
Contributor
Peri Irawan
Format
PDF
Language
ENGLISH
Type
TEXT
Files
Collection
Citation
Yaqi Sheng1 and Huadong Zhu1*, “Case report: a case of AL amyloidosis with spontaneous giant retroperitoneal hematoma,” Repository Horizon University Indonesia, accessed April 25, 2026, https://repository.horizon.ac.id/items/show/12556.