Severe hypertension after atropine administration a case report:

Severe hypertension after atropine administration a case report:

Atropine, Case report, Hypertension

Abstract Atropine, a cholinergic receptor antagonist, counteracts the parasympathetic nervous system’s inhibitory
effects on the sinus node, thereby increasing heart rate. It is frequently used to manage atrioventricular block,
organophosphate and beta-blocker poisoning, and sinus bradycardia. This case report highlights a rare instance
of hypertensive urgency induced by atropine administration, emphasizing the clinical significance of this adverse
effect. We present a case report involving a 48-year-old male patient scheduled for right inguinal hernia surgery. The
patient was administered atropine prior to the procedure and subsequently experienced severe hypertension and
a headache, which were treated with labetalol. After 24 h of monitoring, the patient was discharged without further
complications. Documenting such cases is crucial for enhancing our understanding of atropine’s safety profile and
refining management strategies to mitigate associated risks.
Clinical trial number Not applicable.
Keywords Atropine, Case report, Hypertension

Sara Timerga1* and Aynalem Befkadu1

https://doi.org/10.1186/s12245-025-00832-4

2025

Peri Irawan

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