Primary subdural lymphoma mimicking chronic subdural hematoma: a case reportand a narrative review of some recent similarcases in the literature
Dublin Core
Title
Primary subdural lymphoma mimicking chronic subdural hematoma: a case reportand a narrative review of some recent similarcases in the literature
Subject
Primary subdural lymphoma, Chronic subdural hematoma, Diagnosis, Treatment
Description
Abstract
Background Chronic subdural hematoma (CSDH) is a common condition in elderly patients, typically diagnosed
through neuroimaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI).
Cases of subdural lymphoma mimicking chronic subdural hematoma are exceedingly rare and present significant
diagnostic challenges for emergency physicians.
Case presentation A 71-year-old female patient with subdural lymphoma was initially diagnosed with CSDH based
on her medical history, clinical presentation, and neuroimaging findings. However, postoperative pathology revealed
diffuse subdural lymphoma. Although the patient’s symptoms initially improved following standard lymphoma
treatment, the disease recurred within 14 months of follow-up. The patient ultimately succumbed to malignant
intracranial hypertension 15 months after discharge.
Conclusions This article discusses the neuroimaging findings, histological features, and treatment strategies of
this case, while reviewing the limited number of similar cases reported since 2000. Based on the diagnostic and
therapeutic experience of this case, it is recommended that when a patient’s clinical presentation deviates from
that of typical chronic subdural hematoma, supplementary MRI with diffusion-weighted imaging (DWI) should be
considered to aid in differential diagnosis.
Keywords Primary subdural lymphoma, Chronic subdural hematoma, Diagnosis, Treatment
Background Chronic subdural hematoma (CSDH) is a common condition in elderly patients, typically diagnosed
through neuroimaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI).
Cases of subdural lymphoma mimicking chronic subdural hematoma are exceedingly rare and present significant
diagnostic challenges for emergency physicians.
Case presentation A 71-year-old female patient with subdural lymphoma was initially diagnosed with CSDH based
on her medical history, clinical presentation, and neuroimaging findings. However, postoperative pathology revealed
diffuse subdural lymphoma. Although the patient’s symptoms initially improved following standard lymphoma
treatment, the disease recurred within 14 months of follow-up. The patient ultimately succumbed to malignant
intracranial hypertension 15 months after discharge.
Conclusions This article discusses the neuroimaging findings, histological features, and treatment strategies of
this case, while reviewing the limited number of similar cases reported since 2000. Based on the diagnostic and
therapeutic experience of this case, it is recommended that when a patient’s clinical presentation deviates from
that of typical chronic subdural hematoma, supplementary MRI with diffusion-weighted imaging (DWI) should be
considered to aid in differential diagnosis.
Keywords Primary subdural lymphoma, Chronic subdural hematoma, Diagnosis, Treatment
Creator
Yibo Han1,2†, Bin Chen1,3†, Meiyu Zeng5†, Dong Liang1,4, Yibao Wang1
and Yong Wang1*
and Yong Wang1*
Source
https://doi.org/10.1186/s12245-025-00836-0
Date
2025
Contributor
Peri Irawan
Format
pdf
Language
english
Type
text
Files
Collection
Citation
Yibo Han1,2†, Bin Chen1,3†, Meiyu Zeng5†, Dong Liang1,4, Yibao Wang1
and Yong Wang1*, “Primary subdural lymphoma mimicking chronic subdural hematoma: a case reportand a narrative review of some recent similarcases in the literature,” Repository Horizon University Indonesia, accessed April 11, 2026, https://repository.horizon.ac.id/items/show/12670.