PROSIDING INTERNASIONAL KEPERAWATAN Proceedings of the International Conference on Nursing and Health Sciences Volume 1 No 1, November 2020
TONICUM ACTIVITY TEST OF BIDARA LEAF EXTRACT ON SWIMMING RESISTANCE OF WHITE MALE MICE
Dublin Core
Title
PROSIDING INTERNASIONAL KEPERAWATAN Proceedings of the International Conference on Nursing and Health Sciences Volume 1 No 1, November 2020
TONICUM ACTIVITY TEST OF BIDARA LEAF EXTRACT ON SWIMMING RESISTANCE OF WHITE MALE MICE
TONICUM ACTIVITY TEST OF BIDARA LEAF EXTRACT ON SWIMMING RESISTANCE OF WHITE MALE MICE
Subject
Ziziphus mauritiana L; tonic; swimming mice
Description
The bidara plant (Ziziphus mauritiana L.) is one of the medicinal plants used and trusted by the
wider community for treatment. Traditionally this plant was used as a tonic. Objective : The
purpose of this study was to prove the tonic activity of bidara leaf extract against white male
mice (Mus musculus) and to determine the effective concentration of bidara leaf extract which
has tonic activity against swimming resistance white male mice (Mus musculus). Method :This
research was conducted in February - August 2019 at the Pharmacy Laboratory of the Kendal
College of Health Sciences. The tools and materials used are mice, bidara leaves, ethanol,
glassware, sonde and glass ponds.Leaf extraction of bidara was carried out by maceration method
using 70% ethanol solvent. The design of this study was an experimental study (pre-experimental
desings) in the form of statistical group comparisons. The tonic effect test was carried out using
the mice swimming endurance method. Twenty five white malemice were divided into five
groups. Group I mice were given 0.5% CMC Na (negative control), group II were given Fatigon
(positive control) and groups III, IV, V were given bidara leaf extract concentrations of 50, 100
and 200 mg / kgBW orally. Data analysis was performed by comparing swimming times using
the Kruskal-Wallis test and the Mann-Whitney test with a confidence level of 95%. Result : The
results showed that there were group differences between treatments.Conclusions : The leaf
extract of bidara (Ziziphus mauritiana L.) had tonic activity against white male mice (Mus
musculus) with an effective concentration of 100 mg / kgBW.
wider community for treatment. Traditionally this plant was used as a tonic. Objective : The
purpose of this study was to prove the tonic activity of bidara leaf extract against white male
mice (Mus musculus) and to determine the effective concentration of bidara leaf extract which
has tonic activity against swimming resistance white male mice (Mus musculus). Method :This
research was conducted in February - August 2019 at the Pharmacy Laboratory of the Kendal
College of Health Sciences. The tools and materials used are mice, bidara leaves, ethanol,
glassware, sonde and glass ponds.Leaf extraction of bidara was carried out by maceration method
using 70% ethanol solvent. The design of this study was an experimental study (pre-experimental
desings) in the form of statistical group comparisons. The tonic effect test was carried out using
the mice swimming endurance method. Twenty five white malemice were divided into five
groups. Group I mice were given 0.5% CMC Na (negative control), group II were given Fatigon
(positive control) and groups III, IV, V were given bidara leaf extract concentrations of 50, 100
and 200 mg / kgBW orally. Data analysis was performed by comparing swimming times using
the Kruskal-Wallis test and the Mann-Whitney test with a confidence level of 95%. Result : The
results showed that there were group differences between treatments.Conclusions : The leaf
extract of bidara (Ziziphus mauritiana L.) had tonic activity against white male mice (Mus
musculus) with an effective concentration of 100 mg / kgBW.
Creator
EtikaYulianti, Nita Fajaryanti, Itsna Diah Kusumaningrum
Source
http://jurnal.globalhealthsciencegroup.com/index.php/PICNHS
Publisher
Global Health Science Group
Date
November 2020
Contributor
PERI IRAWAN
Format
PDF
Language
ENGLISH
Type
TEXT
Files
Citation
EtikaYulianti, Nita Fajaryanti, Itsna Diah Kusumaningrum, “PROSIDING INTERNASIONAL KEPERAWATAN Proceedings of the International Conference on Nursing and Health Sciences Volume 1 No 1, November 2020
TONICUM ACTIVITY TEST OF BIDARA LEAF EXTRACT ON SWIMMING RESISTANCE OF WHITE MALE MICE,” Repository Horizon University Indonesia, accessed November 13, 2024, https://repository.horizon.ac.id/items/show/2989.
TONICUM ACTIVITY TEST OF BIDARA LEAF EXTRACT ON SWIMMING RESISTANCE OF WHITE MALE MICE,” Repository Horizon University Indonesia, accessed November 13, 2024, https://repository.horizon.ac.id/items/show/2989.