Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 2 2021
Impact of Metabolic Syndrome on Lower Urinary Tract Symptoms in Patients with Benign Prostate Hyperplasia
Dublin Core
Title
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 2 2021
Impact of Metabolic Syndrome on Lower Urinary Tract Symptoms in Patients with Benign Prostate Hyperplasia
Impact of Metabolic Syndrome on Lower Urinary Tract Symptoms in Patients with Benign Prostate Hyperplasia
Subject
benign prostate hyperplasia, lower urinary tract symptoms, metabolic syndrome
Description
BACKGROUND Studies evaluating the relationship between metabolic syndrome (MetS) and lower urinary tract symptoms (LUTS) in men with benign prostate hyperplasia (BPH) are lacking in Indonesia. This study aimed to discover the association of LUTS and MetS in men with BPH.
METHODS Subjects who underwent biopsy were recruited from Cipto Mangunkusumo Hospital, Jakarta, Indonesia from January 2014 to January 2018, but only men who had biopsy-proven BPH were included. Body mass index, waist circumference, fasting blood glucose, triglyceride, high-density lipoprotein, prostate volume (PV), and international prostate symptom score (IPSS) were collected before the biopsy. MetS criteria were
based on the National Cholesterol Education Program Adult Treatment Panel III. IPSS was assessed for LUTS and consisted of irritative and obstructive symptoms and quality of life (QoL). Independent t-test or Mann–Whitney test was used to analyze numerical data.
RESULTS Of 227 men with biopsy-proven BPH, 87 (38.3%) were diagnosed with MetS. PV was similar in men with or without MetS (54.4 [20.3–100] versus 49.9 [19.5–100] cm3 , p = 0.239). Men with MetS generally had more LUTS (15 [1–30] versus 11 [0–35], p = 0.005), more irritative symptoms (8 [0–20] versus 6 [0–20], p = 0.007), and lower QoL
(4 [0–6] versus 3 [0–6], p = 0.018).
CONCLUSIONS BPH patients with MetS had greater LUTS, particularly irritative symptoms and QoL score.
METHODS Subjects who underwent biopsy were recruited from Cipto Mangunkusumo Hospital, Jakarta, Indonesia from January 2014 to January 2018, but only men who had biopsy-proven BPH were included. Body mass index, waist circumference, fasting blood glucose, triglyceride, high-density lipoprotein, prostate volume (PV), and international prostate symptom score (IPSS) were collected before the biopsy. MetS criteria were
based on the National Cholesterol Education Program Adult Treatment Panel III. IPSS was assessed for LUTS and consisted of irritative and obstructive symptoms and quality of life (QoL). Independent t-test or Mann–Whitney test was used to analyze numerical data.
RESULTS Of 227 men with biopsy-proven BPH, 87 (38.3%) were diagnosed with MetS. PV was similar in men with or without MetS (54.4 [20.3–100] versus 49.9 [19.5–100] cm3 , p = 0.239). Men with MetS generally had more LUTS (15 [1–30] versus 11 [0–35], p = 0.005), more irritative symptoms (8 [0–20] versus 6 [0–20], p = 0.007), and lower QoL
(4 [0–6] versus 3 [0–6], p = 0.018).
CONCLUSIONS BPH patients with MetS had greater LUTS, particularly irritative symptoms and QoL score.
Creator
Dyandra Parikesit, Fiastuti Witjaksono, Chaidir Arif Mochtar, Nur Rasyid, Agus Rizal Ardy Hariandy Hamid
Publisher
Fakultas Kedokteran Universitas Indonesia
Date
2021-06-30
Contributor
Sri Wahyuni
Rights
ISSN : 0853-1773
Format
PDF
Language
English
Type
Text
Coverage
Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 2 2021
Files
Citation
Dyandra Parikesit, Fiastuti Witjaksono, Chaidir Arif Mochtar, Nur Rasyid, Agus Rizal Ardy Hariandy Hamid, “Jurnal Internasional Medical Journal of Indonesia FKUI Vol. 30 No. 2 2021
Impact of Metabolic Syndrome on Lower Urinary Tract Symptoms in Patients with Benign Prostate Hyperplasia,” Repository Horizon University Indonesia, accessed November 21, 2024, https://repository.horizon.ac.id/items/show/985.
Impact of Metabolic Syndrome on Lower Urinary Tract Symptoms in Patients with Benign Prostate Hyperplasia,” Repository Horizon University Indonesia, accessed November 21, 2024, https://repository.horizon.ac.id/items/show/985.