JURNAL INTERNASIONAL KEBIDANAN 2020-2023 UNIVERSITAS KEDOKTERAN GUILAN VOLUME 33 ISSUE 2.
JOURNAL OF HOLISTIC NURSING OF MIDWIFERY.
Comparing Quality of Life Before and After Surgery in
Patients With Cushing Disease: A Before-After Study
Dublin Core
Title
JURNAL INTERNASIONAL KEBIDANAN 2020-2023 UNIVERSITAS KEDOKTERAN GUILAN VOLUME 33 ISSUE 2.
JOURNAL OF HOLISTIC NURSING OF MIDWIFERY.
Comparing Quality of Life Before and After Surgery in
Patients With Cushing Disease: A Before-After Study
JOURNAL OF HOLISTIC NURSING OF MIDWIFERY.
Comparing Quality of Life Before and After Surgery in
Patients With Cushing Disease: A Before-After Study
Subject
Quality of life (QoL), Cushing, Disease
Description
Introduction: Cushing disease is a rare problem that usually has an important effect on the
quality of life (QoL).
Objective: This survey aimed to evaluate patients’ QoL and determine predictors of improving
QoL scores in patients.
Materials and Methods: In this before-after study, basic characteristics were collected
from 56 patients with Cushing disease who underwent endoscopic transsphenoidal
surgery, and their QoL score during one year was assessed. Finally, predictor factors of
QoL score improvement were identified. To compare the QoL scores before, 6 months,
and 12 months after surgery, repeated measures ANOVA and for determining predictors
of QoL score improvement, multivariable logistic regression analysis was used. P<0.05 was
considered significant in all tests.
Results: The Mean±SD age of the samples was 33.92±12.82 years, and 43 (76.8%) were
female. In all 56 patients who underwent endoscopic transsphenoidal surgery, the QoL score
significantly improved. In multivariable logistic regression analysis, weight loss (OR= 1.2, 95%
CI; 1.01-6.5, P=0.01), no fatigue (OR= 2.1, 95%CI; 1.6-8.3, P=0.009), no decreased libido (OR=
1.5, 95% CI; 1.2-10.62, P=0.01), no gonadal axis disorder (OR=2.2, 95% CI; 1.07-4.06, P=0.01)
and post-operation no thyroid axis disorder (OR=2.5, 95% CI; 1.8-5.7, P=0.01) were predictors
for more QoL score improvement.
Conclusion: According to the results of this study, many factors can affect the quality of life in
patients with Cushing disease. Therefore, support groups should include the cooperation of
physicians and psychologists, provision of health services, and social support to improve the
QoL of patients.
quality of life (QoL).
Objective: This survey aimed to evaluate patients’ QoL and determine predictors of improving
QoL scores in patients.
Materials and Methods: In this before-after study, basic characteristics were collected
from 56 patients with Cushing disease who underwent endoscopic transsphenoidal
surgery, and their QoL score during one year was assessed. Finally, predictor factors of
QoL score improvement were identified. To compare the QoL scores before, 6 months,
and 12 months after surgery, repeated measures ANOVA and for determining predictors
of QoL score improvement, multivariable logistic regression analysis was used. P<0.05 was
considered significant in all tests.
Results: The Mean±SD age of the samples was 33.92±12.82 years, and 43 (76.8%) were
female. In all 56 patients who underwent endoscopic transsphenoidal surgery, the QoL score
significantly improved. In multivariable logistic regression analysis, weight loss (OR= 1.2, 95%
CI; 1.01-6.5, P=0.01), no fatigue (OR= 2.1, 95%CI; 1.6-8.3, P=0.009), no decreased libido (OR=
1.5, 95% CI; 1.2-10.62, P=0.01), no gonadal axis disorder (OR=2.2, 95% CI; 1.07-4.06, P=0.01)
and post-operation no thyroid axis disorder (OR=2.5, 95% CI; 1.8-5.7, P=0.01) were predictors
for more QoL score improvement.
Conclusion: According to the results of this study, many factors can affect the quality of life in
patients with Cushing disease. Therefore, support groups should include the cooperation of
physicians and psychologists, provision of health services, and social support to improve the
QoL of patients.
Creator
Arezoo Chouhdari , Omidvar Rezaei , Mohammad Samadian , Guive Sharifi , Kaveh Ebrahimzadeh , Zahra Davoudi
Date
April 2023, Volume 33, Number 2
Contributor
peri irawan
Format
pdf
Language
english
Type
text
Files
Citation
Arezoo Chouhdari , Omidvar Rezaei , Mohammad Samadian , Guive Sharifi , Kaveh Ebrahimzadeh , Zahra Davoudi, “JURNAL INTERNASIONAL KEBIDANAN 2020-2023 UNIVERSITAS KEDOKTERAN GUILAN VOLUME 33 ISSUE 2.
JOURNAL OF HOLISTIC NURSING OF MIDWIFERY.
Comparing Quality of Life Before and After Surgery in
Patients With Cushing Disease: A Before-After Study,” Repository Horizon University Indonesia, accessed September 20, 2024, https://repository.horizon.ac.id/items/show/986.
JOURNAL OF HOLISTIC NURSING OF MIDWIFERY.
Comparing Quality of Life Before and After Surgery in
Patients With Cushing Disease: A Before-After Study,” Repository Horizon University Indonesia, accessed September 20, 2024, https://repository.horizon.ac.id/items/show/986.