The effect of awake prone position in non-intubated patients with COVID-19: A feasibility randomized controlled trial
Dublin Core
Title
The effect of awake prone position in non-intubated patients with COVID-19: A feasibility randomized controlled trial
Subject
COVID-19; prone position; oxygen saturation
Description
Background: The duration of discomfort and clinical benefits of lying prone
in Indonesian clinical settings remain unknown, with the accumulation of
prone hours potentially impacting results.
Purpose: The study aimed to test the effect of awake prone position in non-
intubated patients with covid-19.
Methods: This study used a feasibility randomized control trial. The research
was conducted at two general hospitals in Jakarta, Indonesia. This study
used a computerized random number generator was used to assign patients
to intervention and control groups. The sample is adult patients who admitted
to the hospital with hypoxic respiratory failure due to a positive COVID-19
test. A total of 70 patients were randomly assigned to each group, with 35
individuals being included in the analysis. The intervention involved bed-
side nurses encouraging patients to lie prone for at least 6 hours daily, with
additional pillows provided for comfort. Significant prone position sessions
were recorded if they lasted more than 30 minutes in both arms, lasting for
7 days.
Results: The intervention group of patients achieved 65.7% adherence to
the intervention protocol. After 2 hours, the P/F ratio was significantly different
across the groups, but no significant different between intervention and
control group, in term of respiratory escalation, length of stay, or mortality.
However, 5.7% of patients in intervention group and 11.4% of patients in
control group died due to respiratory failure.
Conclusion: Clinical trial conditions have shown that non-intubated patients
can be placed in an awake prone position without harm, and this information
could be used to help design protocols for future large randomized controlled
trials.
in Indonesian clinical settings remain unknown, with the accumulation of
prone hours potentially impacting results.
Purpose: The study aimed to test the effect of awake prone position in non-
intubated patients with covid-19.
Methods: This study used a feasibility randomized control trial. The research
was conducted at two general hospitals in Jakarta, Indonesia. This study
used a computerized random number generator was used to assign patients
to intervention and control groups. The sample is adult patients who admitted
to the hospital with hypoxic respiratory failure due to a positive COVID-19
test. A total of 70 patients were randomly assigned to each group, with 35
individuals being included in the analysis. The intervention involved bed-
side nurses encouraging patients to lie prone for at least 6 hours daily, with
additional pillows provided for comfort. Significant prone position sessions
were recorded if they lasted more than 30 minutes in both arms, lasting for
7 days.
Results: The intervention group of patients achieved 65.7% adherence to
the intervention protocol. After 2 hours, the P/F ratio was significantly different
across the groups, but no significant different between intervention and
control group, in term of respiratory escalation, length of stay, or mortality.
However, 5.7% of patients in intervention group and 11.4% of patients in
control group died due to respiratory failure.
Conclusion: Clinical trial conditions have shown that non-intubated patients
can be placed in an awake prone position without harm, and this information
could be used to help design protocols for future large randomized controlled
trials.
Creator
Eli Indawati* , Achmad Fauzi , Siti Ida Farida
Source
http://jkp.fkep.unpad.ac.id/index.
php/jkp
php/jkp
Date
April 25, 2025
Contributor
peri irawan
Format
pdf
Language
english
Type
text
Files
Collection
Citation
Eli Indawati* , Achmad Fauzi , Siti Ida Farida, “The effect of awake prone position in non-intubated patients with COVID-19: A feasibility randomized controlled trial,” Repository Horizon University Indonesia, accessed February 12, 2026, https://repository.horizon.ac.id/items/show/10782.